Special Issue "Microalgal Molecules and Enzymes"
Deadline for manuscript submissions: closed (31 July 2021).
Interests: Marine biotechnology, cellular biology, characterization of natural compounds, compound mechanism of action, cell cycle analysis, cell death, search bioactive molecules from microalgae, anti-cancer, anti-oxidant, anti-inflammatory
Interests: Drug discovery; marine biotechnology; microalgae; marine organism exploitation; gene mining; transcriptome analysis; enzyme; bioactivity screening; stress responses; biotechnological applications
Special Issues and Collections in MDPI journals
Microalgae are photosynthetic unicellular organisms that can be massively cultivated under controlled conditions in photobioreactors with relatively small quantities of micro- and macro-nutrients. Microalgae have been shown to be excellent sources of several bioactive molecules such as lipids, carbohydrates, vitamins, pigments and a series of other compounds. Several studies have shown that microalgal raw extracts, fractions and pure compounds had biological activities, such as anticancer, anti-microbial, anti-epilepsy, anti-inflammatory, and immunomodulatory activities. Microalgae are adapted to live in both marine and freshwater environments, as well as in extreme conditions. This capability results in a huge diversity of species, which can produce very different interesting natural products with industrial and pharmaceutical interest. Recent technologies have allowed to sequence genomes, metagenomes, transcriptomes, metatranscriptomes, proteomes, and metabolomes of several microalgal species or pool of species, in silico identifying gene clusters involved in the synthesis of potentially bioactive compounds and helping in the discovery of new drugs from microalgae. These advances in –omics technologies applied to microalgae have allowed the identification of target enzymes, their heterologous expression and functional characterization. In addition microalgae are source of novel enzymes with industrial applications (e.g., lipids and biofuel production, healthcare, and bioremediation) and the modification of enzyme-coding sequences involved in lipid and carotenoid production has resulted in promising results. We would like to encourage the submission in this special issue “Microalgae molecules and enzymes” to collect recent original research and reviews in the field, highlighting microalgal bioactivities and potential development of new molecules and enzymes for biotechnological and industrial applications, such as pharmaceutical, nutraceutical and cosmeceutical sectors.
Dr. Assunta Saide
Dr. Chiara Lauritano
Manuscript Submission Information
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- Bioactive molecules
- Gene expression
- Drug discovery
- Molecular mechanism
- Gene mining
- Industrial applications