Special Issue "Extracellular Vesicles as a New Source of Liquid Biopsy"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 15 November 2020.
Interests: extracellular vesicles; flow cytometry; biomarkers
Within the past decade, extracellular vesicles have progressively emerged as key regulators of organized communities of cells within multicellular organisms in health and disease. Extracellular vesicles have been described as shuttle vectors or signal transducers that can deliver specific biological information even at long distances. Due to their substantial stability, extracellular vesicles circulate through bodily fluids and have been identified in blood, urine, cerebrospinal fluid, saliva, milk, and tears. It is known that extracellular vesicles are a heterogeneous group of lipidic structures ranging from 30–50,000 nm in size, generically subclassified as small, if within 100 nm, and medium/large, if above 100–200 nm.
The extracellular vesicle cargo, consisting of genomic DNA, RNAs, miRNAs, proteins, and lipids dynamically reflecting the characteristics of the cells of origin, makes them an attractive source of biological information. For all of these reasons, extracellular vesicles have high potential as dynamic biomarkers of diseases and/or response to therapies. The deep characterization of extracellular vesicle general characteristics and cargoes related to their roles in tumorigenesis, immunity, and vascular biology may present interesting perspectives in the assessment of extracellular vesicles as a reliable liquid biopsy source.
Dr. Paola Lanuti
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- Apoptotic bodies
- Large oncosomes
- Extracellular vesicles
- Liquid biopsy
- Intercellular communication
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Extracellular vesicle components in liquid biopsies for lung diseases
Title: MiR-365 (microRNA): Potential Biomarker In Oral Squamous Cell Carcinoma Exosomes
Title: Placental Exosomes Revisited
Title: Exosomal RNA of Melanoma Origin Contain Pro-metastasis miRNA and lncRNA