Molecular Genetics of Human Diseases: Focus on Intestinal Cancers
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 2337
Special Issue Editor
Interests: nutrigenomics; epigenetics; gene expression; precision nutrition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Environmental factors, such as nutrition, stress, chemicals, infections, and other factors, have been shown to play a significant role in the development of intestinal cancers. The link between diet and the risk of developing colorectal and other intestinal cancers has long been recognized, but the cellular and molecular mechanisms underlying this connection remain unclear.
Recent research has suggested that epigenetic modifications, including DNA methylation, post-transcriptional modifications of histone, and non-coding RNAs, may play a role in the development of these cancers. In particular, dietary compounds have been shown to influence epigenetic modifications, potentially affecting gene expression and contributing to cancer development. Stem cells in the gut, as well as the gut microbiome, have been identified as targets for further study in this context.
We invite submissions of original research articles, reviews, and meta-analyses that explore the links between dietary exposures, genetic and epigenetic changes, and the risk of intestinal cancers in adulthood. Our goal is to advance our understanding of the cellular and molecular mechanisms underlying the development of these cancers and to develop new strategies for their prevention and treatment.
We believe that this Special Issue will make a valuable contribution to the field and improve public health outcomes related to intestinal cancers. Thank you for your contributions.
Dr. Flores Naselli
Guest Editor
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Keywords
- intestinal cancer
- dietary compound
- nutrigenomics
- DNA methylation
- non-coding RNAs
- histone modifications
- epigenetic changes
- gut microbiome
- intestinal disease
- environmental factors
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