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Genes publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research on Genetics and Breeding of Rice

edited by Xiaojin Luo

submission deadline 20 Jun 2026 | 1 articles | Viewed by 235 | Submission Open

Keywords: rice breeding; molecular genetics; rice germplasm; QTL identification and gene cloning; genetic function and genetic network; breeding technologies

(This special issue belongs to the Section Plant Genetics and Genomics)

Advancements in Pharmacogenomics for Precision Medicine

edited by

Óscar Teijido Hermida

submission deadline 20 Jun 2026 | Viewed by 108 | Submission Open

Keywords: pharmacogenomics; precision medicine; pharmacoepigenomics; epidrugs; genomic biomarkers; drug response variability; personalized therapy; multi-omics integration; pharmacogenetic testing; clinical implementation; artificial intelligence in pharmacogenomics; genetic polymorphisms; translational genomics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Advances in Genomic Surveillance of Pathogens

edited by Rachel R. Spurbeck

submission deadline 20 Jun 2026 | Viewed by 46 | Submission Open

Keywords: biosurveillance; pathogen detection; host response; epigenomics; genomics; transcriptomics; viromics; microbiome analysis; shotgun metagenomics

(This special issue belongs to the Section Microbial Genetics and Genomics)

The CranioFacial Biology Group at the University of Adelaide Collection: Genetic, Epigenetic and Environmental Factors in Complex Adaptive Systems, Multilayer Complex Interactive Networks, and Multiple Models During Oral Development

edited by

Alan H. Brook

and Matthew Brook O'Donnell

submission deadline 25 Jun 2026 | 2 articles | Viewed by 3382 | Submission Open

Keywords: oral development; genetics; epigenetics; complex adaptive systems; multilayer complex interactive networks; multiple models

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Insights into the Genomic and Genetic Basis of Cardiovascular Disease

edited by Marzia de Biasio and

Donato Gemmati

submission deadline 25 Jun 2026 | 2 articles | Viewed by 1615 | Submission Open

Keywords: recurrent idiopathic pericarditis and perimyocarditis; spontaneous coronary dissection; sudden idiopathic cardiac death; idiopathic atrial fibrillation; cardio-oncology and cardio toxicity of anti anti-cancer drugs

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic Epidemiology of Multifactorial Diseases

edited by

Maria Tziastoudi

and Ioannis Stefanidis

submission deadline 25 Jun 2026 | 1 articles | Viewed by 970 | Submission Open

Keywords: genetic association studies; polygenic risk scores; functional genomics; causal inference; mendelian randomization; translational applications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Structural and Evolutionary Perspectives on Immunogenetic Variation in Autoimmune and Related Disorders

edited by Athena Andreou and Catriona Kelly

submission deadline 25 Jun 2026 | Viewed by 279 | Submission Open

Keywords: gene polymorphisms; exonic and intronic variants; structural biology; biophysical analysis; structural evolution; protein molecular function and evolution; immunological biomarkers; human genetic diseases; evolutionary genomics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Plant Pathogenic Fungi: Molecular Systematics, Genomics and Evolution

edited by

Shengxiong Huang

submission deadline 25 Jun 2026 | Viewed by 121 | Submission Open

Keywords: plant pathogenic fungi; pathogen isolation and identification; molecular evolution; multi-omics analysis; genome sequencing; comparative genomics; RNA-seq

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetic Mechanisms of Wild Animal Adaptation to the Environment

edited by

Jianhai Chen

submission deadline 25 Jun 2026 | Viewed by 120 | Submission Open

Keywords: wild animal adaptation; evolutionary genomics; population genetics; local adaptation; adaptive introgression; natural selection; genomic variation; functional genomics; environmental stress response; climate adaptation; host– pathogen interaction; epigenetic regulation; multi-omics integration; conservation genomics; genotype– phenotype association

(This special issue belongs to the Section Animal Genetics and Genomics)

Genetic Basis and Molecular Mechanism of Plant Immunity

edited by

Aijun Wang

and Desuo Yin

submission deadline 25 Jun 2026 | Viewed by 38 | Submission Open

Keywords: plant; phytopathogens; immune responses; molecular mechanisms; regulatory pathways; interactions mechanisms

(This special issue belongs to the Section Plant Genetics and Genomics)

Monogenic Diabetes—from Basic Scientific Insights to Precision Care and Beyond

edited by Kathy HC Wu

submission deadline 25 Jun 2026 | Viewed by 31 | Submission Open

Keywords: MODY; precision; implementation; diversity; equity; bioinformatics; functional genomics; genotype; phenotype; high throughput

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic Mechanisms and Therapeutic Strategies in Ovarian Cancer

edited by Aimee Stablewski

submission deadline 25 Jun 2026 | Viewed by 27 | Submission Open

Keywords: epithelial ovarian cancer (EOC); genetic alterations; epigenetic regulation; tumor microenvironment; therapeutic strategies

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genomic and Transcriptomic Advances in Amyotrophic Lateral Sclerosis (ALS) and Motor Neuron Diseases (MND)

edited by

Francesca Dragoni

and

Stella Gagliardi

submission deadline 5 Jul 2026 | Viewed by 195 | Submission Open

Keywords: ALS ; transcriptomic studies ; motor neuron diseases ; biomarkers assessment ; pathomechanisms ; genetics ; genotype– phenotype correlation

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Insights into RNA Coding and Transcriptional Regulation

edited by Zihua Hu

submission deadline 10 Jul 2026 | Viewed by 327 | Submission Open

Keywords: RNA coding; transcriptomics; non-coding RNAs (ncRNA); long non-coding RNA (lncRNA); microRNA (miRNA); RNA modifications; RNA splicing; RNA editing; RNA in transcriptional and post-transcriptional regulation; gene expression regulation; scRNA

(This special issue belongs to the Section RNA)

Advances in Molecular Genetics of Rare Disorders

edited by Miriam Lucia Carriero

submission deadline 10 Jul 2026 | Viewed by 52 | Submission Open

Keywords: rare diseases; molecular genetics; gene– disease associations; genotype– phenotype correlation; targeted gene therapy; next-generation sequencing; whole-genome sequencing; genome-wide association studies; functional genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Autism: Genetics, Environment, Pathogenesis, and Treatment

edited by

Alessandra Mezzelani

submission deadline 10 Jul 2026 | Viewed by 18 | Submission Open

Keywords: Autism Spectrum Disorders (ASDs); pathogenesis; genetic factors; environmental factors; epigenetics; gut microbiota; animal models; organoid models; multi-omics; bioinformatics; biostatistics; biomarkers; diagnosis; patient stratification; personalized interventions

(This special issue belongs to the Section Neurogenomics)

Genetic and Molecular Mechanisms of Plant–Fungal Pathogen Interactions

edited by

Guihua Li

submission deadline 10 Jul 2026 | Viewed by 6 | Submission Open

Keywords: plant– fungal pathogen interactions; fungal pathogenicity; plant immunity; host– pathogen coevolution; effector biology; virulence factors; disease resistance; genetic regulation; molecular mechanisms; omics technologies; genome editing; sustainable crop protection

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetic and Molecular Insights into Migraine

edited by

Maria Papasavva

and Vasileios Siokas

submission deadline 15 Jul 2026 | Viewed by 128 | Submission Open

Keywords: neurosciences; neurology; neurogenetics; molecular neurology; neurodegeneration; neurorehabilitation; rTMS

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic and Epigenetic Mechanisms in Animal Reproduction

edited by Ming Shen

submission deadline 15 Jul 2026 | Viewed by 60 | Submission Open

Keywords: animal reproduction; genetic regulation; epigenetic modification; DNA methylation; histone modification; noncoding rna; chromatin remodeling; gametogenesis; fertilization; embryonic development; reproductive efficiency; reproductive disorders; gene expression; livestock breeding; reproductive biotechnology

(This special issue belongs to the Section Animal Genetics and Genomics)

Advances in Genetics and Genomics of Medical Plants

edited by

Mingcheng Wang

submission deadline 15 Jul 2026 | Viewed by 28 | Submission Open

Keywords: medicinal plant genomics; medicinal plant genetics; high-throughput sequencing; functional genomics; multi-omics integration

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetics and Genomics of Plant Reproductive Development

edited by

Pingli Lu

submission deadline 20 Jul 2026 | Viewed by 131 | Submission Open

Keywords: genetics; genomics; meiosis; anther development; gametophyte development; fertilization; seed; fruit

(This special issue belongs to the Section Plant Genetics and Genomics)

Fetal Genetic Disorders: Diagnosis and Therapy

edited by Gianluca Campobasso

submission deadline 20 Jul 2026 | Viewed by 129 | Submission Open

Keywords: fetal medicine; malformations; ; genetic anomalies; ; genomic sequencing; ; syndromes; artificial intelligence

(This special issue belongs to the Section Genetic Diagnosis)

Environmental Genomics and Low-Dose Induced Adaptive Response: Underlying Mechanisms from Cells to Organisms

edited by

Stephka Chankova

, Michaela Beltcheva and

Teodora Todorova

submission deadline 20 Jul 2026 | Viewed by 64 | Submission Open

Keywords: environmental genomics; ecotoxicology; low-dose induced adaptive response; low-dose radiation; genomic instability; environmental mutagenesis; DNA repair; radio-protection; stress response; toxicogenomics; antioxidant system; chaperone system

(This special issue belongs to the Section Genes & Environments)

Genetics and Diagnosis of Colorectal Cancer

edited by

Shiki Fujino

submission deadline 10 Aug 2026 | Viewed by 119 | Submission Open

Keywords: colorectal cancer; genetics; diagnosis; biomarkers; molecular profiling; cancer stem cell

(This special issue belongs to the Section Genetic Diagnosis)

Buffalo Genetics and Genomics

edited by

Qingyou Liu

and Laiba Shafique

submission deadline 15 Aug 2026 | 4 articles | Viewed by 7869 | Submission Open

Keywords: buffaloes; ruminant; genomics; genetics; evolution; structural characterization

(This special issue belongs to the Section Animal Genetics and Genomics)

Genomic and Molecular Determinants of HPV-Related Reproductive Health

edited by

Nektaria Zagorianakou

and

Efthalia Moustakli

submission deadline 15 Aug 2026 | Viewed by 121 | Submission Open

Keywords: human papillomavirus (HPV); viral genomics; epigenomics; proteomics; vaginal microbiome; intestinal microbiome; metabolic pathways; oxidative stress; infertility genetics; reproductive health; personalized medicine; precision medicine; AI-driven diagnostics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Forage and Grass Genetics and Genomics

edited by Peizhi Yang, Jinghui Gao,

Yuman Cao

and Tieyuan Liu

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1021 | Submission Open

Keywords: molecular genetics; proteomics; polyploid genomes; genotype– phenotype association analysis; forage gene editing; biotic or abiotic stress; inter-biological interactions

(This special issue belongs to the Section Plant Genetics and Genomics)

The Effects of Polygenic Interactions on Mental Health

edited by Henri M. Garrison-Desany

submission deadline 25 Aug 2026 | Viewed by 27 | Submission Open

Keywords: polygenic risk; neuropsychiatric disorders; psychiatric genetics; interaction analyses; gene-environment interactions; multiomics; precision psychiatry

(This special issue belongs to the Section Neurogenomics)

Genetic Architecture of Wheat Domestication- and Improvement-Related Traits

edited by Panfeng Guan

submission deadline 10 Sep 2026 | Viewed by 56 | Submission Open

Keywords: wheat; origin and evolution; domestication syndrome; genetic diversity; genetic improvement; gene mapping and cloning; molecular mechanism and function; molecular breeding; pan-omics; new approaches

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetics of Neuromuscular Disorders

edited by Nyamkhishig Sambuughin

submission deadline 10 Sep 2026 | Viewed by 34 | Submission Open

Keywords: hereditary neuromuscular disorders; functional studies; disease mechanisms; variant pathogenicity; animal and cell culture model of neuromuscular disorders

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Mitochondrial DNA Variation in Health and Disease

edited by Ludmiła A. Grzybowska-Szatkowska, Katarzyna Bartosik and Marzanna Ciesielka

submission deadline 15 Sep 2026 | Viewed by 16 | Submission Open

Keywords: mitochondrial DNA; single-nucleotide polymorphism; carcinogenesis; apoptosis; mitochondrial haplogroups

(This special issue belongs to the Section Molecular Genetics and Genomics)

Hereditary Traits and Diseases in Companion Animals

edited by

Lucie Chevallier

and

Marie Abitbol

submission deadline 25 Sep 2026 | 3 articles | Viewed by 3358 | Submission Open

Keywords: genetic traits; hereditary diseases; companion animals; spontaneous disease models; veterinary genetics; genetic selection; breed-specific diseases

(This special issue belongs to the Section Animal Genetics and Genomics)

Aquatic Germplasm Resources and Genetic Breeding

edited by Wei Song

submission deadline 15 Oct 2026 | Viewed by 11 | Submission Open

Keywords: fish; shrimp; shellfish; algae; geographical population; morphological difference; cytochrome oxidase subunit I (COI); microsatellites; genetic structure; genetic diversity; gene cloning; cellular localization; RNAi; gene overexpression

(This special issue belongs to the Section Animal Genetics and Genomics)

Feature Papers: Molecular Genetics and Genomics 2026

edited by

Albert Jeltsch

and

Paolo Cinelli

submission deadline 25 Dec 2026 | Viewed by 72 | Submission Open

Keywords: single-cell and spatial omics; genome-targeted RNA therapeutics and diagnostics; next-generation CRISPR genome and epigenome editing; chromatin remodeling and dynamics; epigenetics; DNA methylation; histone modification; histone code; DNA replication; repair; recombination; mobile DNA; mitochondrial DNA; RNA biology and molecular regulation; molecular mechanisms of cell signaling; signal transduction; cell cycle; cell death; and stem cell regulation; post-transcriptional regulation of gene expression; developmental genetics; AI-powered genomics and genetics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Feature Papers in "Neurogenetics and Neurogenomics": 2026

edited by