Social Implementation of Advanced Gel Materials

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".

Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 5712

Special Issue Editors


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Guest Editor
National Institute of Technology (NIT), Okinawa College, 905 Henoko, Nago, Okinawa 905-2192, Japan
Interests: polymer brush; ionic liquids; polymer electrolyte; super capacitor; fibers; gel; ion gels; gel electrolyte; soft tribology material
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Faculty of Pharmaceutical Science, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba, Sendai, Miyagi 981-8558, Japan
Interests: biosensor; analytical chemistry; electrochemistry

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Guest Editor
Department of Creative Engineering, National Institute of Technology, Tsuruoka College, 104 Sawada, Inooka, Tsuruoka, Yamagata 997-8511, Japan
Interests: tribology; functional materials; analytical chemistry; gels; ion gels

Special Issue Information

Dear Colleagues,

Many papers have been published on the science and technology of gel materials. Recently, gel materials with ultra-high strength, self-healing properties, and biocompatibility have been developed, and new gels are also being developed, including structures that degrade in nature. These gel materials are used as electrolytes in lithium secondary batteries, sensor probes, cushioning materials, and low-friction materials. A wide range of research is being conducted, from basic research to applied research to practical materials. In this context, this Special Issue welcomes papers on gel materials that are aimed at or have been put into practical use. The practical use of gels requires great ingenuity, not only in the chemical composition and molecular structure of the gel but also in its engineering, including thinning, molding, bonding with different materials, dimensional stability, heat resistance, and durability. This Special Issue welcomes papers that focus not only on the basic chemistry of gels with new functions, but also on the engineering for practical application of gels.

Prof. Dr. Takaya Sato
Dr. Katsuhiko Sato
Prof. Dr. Toshio Kamijo
Guest Editors

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Keywords

  • hydrophilic- and lipophilic-gels
  • polymers for gels
  • electrochemistry of gels
  • biosensing application of gels
  • self-remediation of gels
  • chemistry and engineering of gels
  • battery and capacitor application of gels
  • biocompatibility and biodegradability of gels
  • film and coating of gels
  • ionic liquids application for gels
  • 3D-printing of gels
  • manufacturing of gels
  • target drug and cosmetics application of gels
  • structure and cross linkage of gels
  • industrial application of gels

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Published Papers (3 papers)

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Research

14 pages, 2656 KiB  
Article
A Paintable Small-Molecule Hydrogel with Antimicrobial and ROS Scavenging Activities for Burn Wound Healing
by Qingchun Ji, Kehan Chen, Han Yi, Bingfang He and Tianyue Jiang
Gels 2024, 10(10), 621; https://doi.org/10.3390/gels10100621 - 26 Sep 2024
Cited by 1 | Viewed by 1660
Abstract
Delayed wound healing induced by bacterial infection and a persistent inflammatory response remains a great clinical challenge. Herein, we reported a paintable, anti-bacterial, and anti-inflammatory Nap-F3K-CA (Nap-Phe-Phe-Phe-Lys-Caffeic Acid) hydrogel for burn wound management based on caffeic acid (CA)-functionalized short peptides (Nap-Phe-Phe-Phe-Lys). Hydrogels are [...] Read more.
Delayed wound healing induced by bacterial infection and a persistent inflammatory response remains a great clinical challenge. Herein, we reported a paintable, anti-bacterial, and anti-inflammatory Nap-F3K-CA (Nap-Phe-Phe-Phe-Lys-Caffeic Acid) hydrogel for burn wound management based on caffeic acid (CA)-functionalized short peptides (Nap-Phe-Phe-Phe-Lys). Hydrogels are assembled by non-covalent interactions between gelators, and the incorporation of CA promotes the self-assembly of the hydrogel. After being applied to burn wounds, the hydrogel effectively adapted to irregular wound beds and maintained a moist protective environment at the wound. The Nap-F3K-CA hydrogel can scavenge ROS to relieve oxidative damage and downregulate proinflammatory levels. The Nap-F3K-CA hydrogel also displayed potent antibacterial activity against Gram-positive and Gram-negative bacteria, which reduced the incidence of wound infections. Moreover, the hydrogel exhibited good biocompatibility and hemostatic function. In vivo experiments demonstrated that the Nap-F3K-CA hydrogel significantly accelerated the repair of the skin structure including promoting collagen deposition, vascular regeneration, and hair follicle formation. These findings proved the clinical application potential of the Nap-F3K-CA hydrogel as a promising burn wound dressing. Full article
(This article belongs to the Special Issue Social Implementation of Advanced Gel Materials)
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17 pages, 5388 KiB  
Article
Development and Geometrical Considerations of Unique Conductive and Reversible Carbon-Nanotube Hydrogel without Need for Gelators
by Ryo Ogawa, Ryota Arakaki and Takahide Oya
Gels 2024, 10(7), 457; https://doi.org/10.3390/gels10070457 - 12 Jul 2024
Cited by 2 | Viewed by 1352
Abstract
We propose a new type of CNT hydrogel that has unique conductive and reversible characteristics. We found in previous studies that CNT dispersions became gelatinous without any gelators when a specific CNT was combined with a specific dispersant. This hydrogel has conductive properties [...] Read more.
We propose a new type of CNT hydrogel that has unique conductive and reversible characteristics. We found in previous studies that CNT dispersions became gelatinous without any gelators when a specific CNT was combined with a specific dispersant. This hydrogel has conductive properties derived mainly from the CNTs it contains; and even after gelation, it can be returned to a liquid state by ultrasonic irradiation. Furthermore, the liquid is gelable again. In this study, we prepared several types of CNTs and several types of dispersants, experimentally verified the possibility of gelation by combining them, and geometrically investigated the gelation mechanism to determine how this unique hydrogel is formed. As a result, we found that the experimental results and the theory examined in this study were consistent with the combination of materials that actually become hydrogels. We expect that this study will allow us to anticipate whether or not an unknown combination of CNTs and dispersants will also become gelatinous. Full article
(This article belongs to the Special Issue Social Implementation of Advanced Gel Materials)
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14 pages, 4825 KiB  
Article
Effects of Doxycycline-Loaded NO-Releasing Nanomatrix Gel on Delayed Replanted of Rat Molar
by Mi Ja Ko, Mi Sun Kim, Hyo-Seol Lee, Ok Hyung Nam, Yong Kwon Chae and Sung Chul Choi
Gels 2024, 10(4), 213; https://doi.org/10.3390/gels10040213 - 22 Mar 2024
Viewed by 1572
Abstract
Background/Aim: Tooth avulsion and delayed replantation may cause inflammatory responses and root resorption of the tooth. The aim of this study is to investigate the effect of a doxycycline-loaded nitric oxide-releasing nanomatrix (DN) gel on the delayed replantation of avulsed rat teeth, with [...] Read more.
Background/Aim: Tooth avulsion and delayed replantation may cause inflammatory responses and root resorption of the tooth. The aim of this study is to investigate the effect of a doxycycline-loaded nitric oxide-releasing nanomatrix (DN) gel on the delayed replantation of avulsed rat teeth, with a focus on assessing the gel’s potential to promote regeneration and inhibit complications associated with the replantation process. Materials and Methods: Twenty-four right maxillary first molars from male Sprague-Dawley rats were atraumatically extracted using sterile extraction forceps. The molars were dried for 1 h at room temperature (approximately 23 °C) and divided into four groups according to the root conditioning methods after extra-alveolar 60-min drying: Group 1, no root conditioning treatment prior to replantation; Group 2, soaking in 2% NaF solution for 5 min before replantation; Group 3, 5-min soaking in NO gel and injection of the gel into the alveolar socket; Group 4, 5-min soaking in DN gel and injection of the gel into the alveolar socket before replantation. The animals were euthanized four weeks after the operation and the specimens were evaluated histologically. Results: The use of NO gel alone showed better anti-inflammatory and periodontal effects than the control group, but it did not show a significant effect compared to the group using NaF. When using NO gel loaded with doxycycline, it showed a significant anti-inflammatory effect compared to the control group and showed a similar inhibitory effect to the group using NaF. Conclusions: Within the limits of this study, in delayed replantation situations, the control of inflammatory resorption and replacement resorption is an important factor for achieving a better prognosis of replanted teeth. Root surface treatment with DN gel decreased root resorption after delayed replantation. Full article
(This article belongs to the Special Issue Social Implementation of Advanced Gel Materials)
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