Advances in Gastrointestinal Cancer

Dear Colleagues,

Gastrointestinal (GI) cancer is the fourth most common cancer, which leads to a considerable number of cancer-related deaths worldwide. GI cancer consists of a heterogeneous group of cancers with wide ranging anatomic sites, etiology, pathogenesis, molecular aberrations, histological features, and clinical outcomes. It mostly involves the esophagus, stomach, liver and biliary tract, gallbladder, pancreas, colon, and rectum. To date, surgery remains the mainstay of early-stage GI cancer; chemotherapy is the therapeutic cornerstone in unresectable and metastatic GI cancer. However, an increasing number of targeted therapy strategies have been developed based on recent studies that have disclosed the genetic and molecular biological and immune landscapes of various GI cancers. The emerging integration of multi-omic profiling will also lead to the identification of distinct molecular subtypes with diverse clinical behaviors. With the above-mentioned efforts, the management of GI cancer is now moving toward precision- and evidence-based personalized therapeutics.

Accordingly, the aim of this Special Issue is to deliver the most up-to-date concepts for GI cancer diagnosis, classification, prognostication, surgical and pharmaceutical treatment, and biomarker identification. With the scope to eliminate the gaps between clinical and basic research, studies conducted in a translational manner will be given priority for this issue.

Prof. Dr. Chien-Feng Li
Dr. Ching-Chieh Yang
Dr. Nai-Jung Chiang
Guest Editors

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