Biosensor Applications in Food Safety and Quality Monitoring

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Analytical Methods".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 1040

Special Issue Editor


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Guest Editor
College of Food Science, South China Agricultural University, Guangzhou 510642, China
Interests: food analysis; immunoassay; antibody engineering; hapten design; biosensor; food safety; nanomaterials
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Special Issue Information

Dear Colleagues,

The assurance of food safety and the maintenance of high food quality are paramount global challenges, directly impacting public health, economic stability, and consumer trust. Traditional methods for detecting contaminants, pathogens, and quality indicators, while reliable, often face limitations in terms of analysis time, cost, portability, and the need for specialized personnel. There is, therefore, an urgent and continuous demand for innovative analytical tools that can deliver rapid, sensitive, specific, and on-site results.

In this context, biosensor technology has emerged as a revolutionary force in food science and technology. By integrating a biological recognition element (e.g., enzyme, antibody, nucleic acid, aptamer, or whole cell) with a physicochemical transducer, biosensors offer unparalleled advantages for the real-time and decentralized monitoring of food matrices. The convergence of nanotechnology, materials science, and microengineering has further propelled the development of biosensors, leading to significant enhancements in their sensitivity, selectivity, and multiplexing capabilities.

This Special Issue, "Biosensor Applications in Food Safety and Quality Monitoring", aims to curate a collection of high-quality research papers and review articles that highlight the latest breakthroughs and future trends in this dynamic field. We seek to explore the entire spectrum of biosensor development and application, from fundamental design and novel bioreceptor discovery to robust validation in complex food samples and practical implementation in the supply chain.

We invite contributions that address, but are not limited to, the following topics:

  1. Novel Biosensing Platforms: Development of electrochemical, optical, piezoelectric, and thermal biosensors; paper-based and wearable biosensors; lab-on-a-chip and microfluidic devices.
  2. Advanced Biorecognition Elements: Discovery and engineering of aptamers, molecularly imprinted polymers (MIPs), recombinant antibodies, peptides, and phage-based probes.
  3. Nanomaterial-Enhanced Biosensing: Utilization of graphene, carbon nanotubes, metal and metal-oxide nanoparticles, quantum dots, and upconversion nanoparticles to amplify signals and improve biosensor performance.
  4. Applications in Food Safety: Rapid detection of foodborne pathogens (e.g., Salmonella, Listeria, E. coli), mycotoxins, pesticide residues, veterinary drug residues, heavy metals, and allergens.
  5. Applications in Food Quality Control: Monitoring of freshness indicators (e.g., biogenic amines, ATP), nutritional components, authenticity, adulteration, and genetic modifications.
  6. Point-of-Need/Use Biosensors: Designs for in-field testing, at processing plants, in retail environments, or even by consumers themselves.
  7. Multiplexed and High-Throughput Systems: Platforms capable of simultaneous detection of multiple analytes for comprehensive food profiling.

We believe that this Special Issue will serve as a critical reference for researchers, industry professionals, and regulators, fostering innovation and collaboration to build a safer and more transparent global food system. We look forward to receiving your cutting-edge research.

Dr. Xiangmei Li
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensor
  • food safety
  • food quality
  • rapid detection
  • pathogen
  • mycotoxin
  • aptasensor
  • electrochemical biosensor
  • optical biosensor
  • point-of-care testing

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Published Papers (1 paper)

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Research

16 pages, 2591 KB  
Article
Class-Specific Immunochromatographic Assay Enabled by Mesoporous Nanozyme-Catalyzed Signal Amplification for On-Site Screening of Sulfonylureas
by Yanting Li, Zixian He, Pengjie He, Zixuan Tang, Esra Bağda, Efkan Bağda, Zhenlin Xu and Xiangmei Li
Foods 2026, 15(5), 944; https://doi.org/10.3390/foods15050944 - 7 Mar 2026
Viewed by 524
Abstract
Conventional immunochromatographic assays (ICAs) face limitations in sensitivity and dynamic range, hindering their application in on-site, class-specific screening of sulfonylurea (SU) adulteration in functional foods. To address this, a signal amplification strategy was developed by engineering high-density platinum nanozymes on a mesoporous metal–organic [...] Read more.
Conventional immunochromatographic assays (ICAs) face limitations in sensitivity and dynamic range, hindering their application in on-site, class-specific screening of sulfonylurea (SU) adulteration in functional foods. To address this, a signal amplification strategy was developed by engineering high-density platinum nanozymes on a mesoporous metal–organic framework (PCN-224). The mesoporous architecture of PCN-224 facilitated high-density and stable loading of catalytically active Pt sites. The established PCN-224@Pt-based ICA achieved detection limits of 0.52–7.94 μg/kg in tea and 0.69–7.02 μg/kg in capsules, with linear ranges of 1.69–513.01 μg/kg and 2.05–716.47 μg/kg, respectively. Compared with traditional colloidal gold immunochromatographic assays (CG-ICAs), sensitivity was improved by up to 57-fold, while the linear detection range was expanded by over 5-fold relative to the previously reported PCN-224@PDA- ICA. The method demonstrated recovery rates of 81.8–119.8% and coefficients of variation between 2.5% and 11.4%. Validation against LC-MS/MS using 20 real samples showed excellent agreement (R2 > 0.99). This work not only provides a sensitive and rapid tool for the surveillance of SU adulteration in functional foods but also establishes a generalizable nanozyme design strategy applicable to enhancing the performance of a wide range of ICA-based detection platforms. Full article
(This article belongs to the Special Issue Biosensor Applications in Food Safety and Quality Monitoring)
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