Innovative Technologies of Control and Intervention for Foodborne Pathogens in Foods

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Quality and Safety".

Deadline for manuscript submissions: 10 June 2025 | Viewed by 1161

Special Issue Editor


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Guest Editor
School of Food ann Biological Engineering, Hefei University of Technology, Hefei 230009, China
Interests: control of pathogenic microorganism; control of microbial toxin; adaptation mechanism of microorganism to environmental stress; phage therapy; bacteriophage-host interaction

Special Issue Information

Dear Colleagues,

Since the discovery of antibiotics, their use and abuse have led to the development and spread of antibiotic resistance. This misuse of antibiotics has been reported not only in human and veterinary practices but also in industrial and agricultural practices that have increased the prevalence of drug resistance among most bacterial strains. Developing innovative technologies of control and intervention for foodborne pathogens in foods and novel alternatives to antibiotics has become a common challenge in the food industry.

This Special Issue "Innovative Technologies of Control and Intervene for Foodborne Pathogens in Foods" is intended to contain both reviews and original articles focussed on the emerging data in the field, and on supporting the viability of this approach in an area with real unmet needs. With invited articles contributed by experts from around the world, it is intended to form a valuable resource for both workers in the field and curious newcomers.

Dr. Na Ling
Guest Editor

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Keywords

  • foodborne pathogens
  • food safety
  • antibacterial strategies
  • phage therapy
  • antibiotic resistance

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Published Papers (1 paper)

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Research

17 pages, 2128 KiB  
Article
Assessment of the Anti-Listeria Effect of Citrus limon Peel Extract In Silico, In Vitro, and in Fermented Cow Milk During Cold Storage
by Wafa Mkadem, Khaoula Belguith, Valentina Indio, Olfa Oussaief, Gulnara Guluzade, Halima ElHatmi, Andrea Serraino, Alessandra De Cesare and Nourhene Boudhrioua
Foods 2025, 14(4), 661; https://doi.org/10.3390/foods14040661 - 15 Feb 2025
Cited by 1 | Viewed by 681
Abstract
In this study, the antimicrobial effect of Citrus limon peel extract against Listeria monocytogenes was analyzed in silico, tested in vitro, and validated in fermented cow milk during cold storage. The in silico analysis revealed that 4,5-di-O-caffeoyquinic acid interacts with L. monocytogenes proteins [...] Read more.
In this study, the antimicrobial effect of Citrus limon peel extract against Listeria monocytogenes was analyzed in silico, tested in vitro, and validated in fermented cow milk during cold storage. The in silico analysis revealed that 4,5-di-O-caffeoyquinic acid interacts with L. monocytogenes proteins involved in colonization and intracellular survival. The in vitro experiments demonstrated that the anti-Listeria activity of Citrus limon peel extract is primarily attributed to limonene and phenolic compounds. In fermented milk stored at 4 °C for 7 days, the addition of Citrus limon peel extract resulted in a 2 Log reduction of L. monocytogenes compared to the control. Using the Baranyi and Roberts model, a significant decrease in the maximum growth rate (−0.021 h−1) and the concentration of L. monocytogenes from 5.95 to 3.67 log CFU/mL was observed in fermented milk supplemented with a 2×MIC level of Citrus limon peel extract during storage at 4 °C. The findings from all three approaches highlighted that the inhibitory effect of Citrus limon peel extract against L. monocytogenes is primarily due to chlorogenic acid derivatives, especially 4,5-di-O-caffeoyquinic acid, and limonene. Beyond its antimicrobial properties, the supplementation of fermented milk with Citrus limon peel extract also enhances the milk antioxidant capacity and total organic acids content. Full article
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