Interactions Between Gut Microbiota and Food Bioactive Components: Implications for Health

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Microbiology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 946

Special Issue Editors


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Guest Editor
School of Applied Sciences (FCA), State University of Campinas, 1300 Pedro Zaccaria St., Limeira 13484-350, SP, Brazil
Interests: probiotics; food microbiology; dairy microbiology; food safety; dairy technology; food quality

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Guest Editor
Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, SP, Brazil
Interests: probiotics; prebiotics; synbiotics; postbiotics; functional foods; experimental nutrition; metabolic syndrome; gut microbiome; vaginal microbiome

Special Issue Information

Dear Colleagues,

It is with great pleasure that we would like to invite you to collaborate to this Special Issue that will address the interactions between bioactive components of the diet and the process of modulation of the gut microbiota, especially its implications for health.

In this sense, the main objective of this Special Issue is to deepen existing knowledge about the interrelationship between the gut microbiota, the metabolites it produces, and other components naturally present in food, which can benefit the health of hosts in multiple ways. From the time of Antony van Leeuwenhoek (1632–1723), through Louis Pasteur (1822–1895), Robert Koch (1843–1910), and Élie Metchnikoff (1845–1916) to the present day, the microbial universe has fascinated countless scientists. Initially, the focus was on the study of pathogens, but the existence of cultures of interest for the production of fermented foods also gained notoriety. At the same time, it was suspected that certain microorganisms have a special property that benefits the health of their hosts.

In turn, it is known that the microbiota has a diversity of microbes that colonize the gastrointestinal tract in a number greater or equivalent to than the number of human cells. Although the literature presents several studies that demonstrate that the microbiota is directly related to the well-being of the host, the process of dysbiosis may lead to the worsening of inflammatory processes, as well as the development of some chronic non-communicable diseases. In view of this, more studies are still needed to understand in more detail this relationship between the therapeutic potential of bioactive compounds in the diet and the modulation of the gut microbiota, including mechanisms of action, genetic factors associated with the host, and the regulation of metabolism.

For these reasons, this Special Issue was prepared to bring together recent studies addressing the supplementation of bioactive compounds and their relationship to gut microbiota modulation, including, but not limited to, the following:

  • “Live Dietary Microbes”, beneficial microbes, probiotics, and potentially probiotic microorganisms for human health;
  • Food products aided by bioactive ingredients and health benefits;
  • Functional foods and gut microbiota modulation;
  • Pre-, pro-, syn-, psycho-, and postbiotics for health promotion;
  • Infant gut microbiota and bioactive ingredients;
  • Functional foods and implications for the gut–vagina axis;
  • Relationship between next-generation probiotics and gut microbiota;
  • Bioactive compounds and in vitro models that simulate the human gut microbiota.

Prof. Dr. Adriane Elisabete Costa Antunes
Dr. Douglas Xavier-Santos
Guest Editors

Manuscript Submission Information

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Keywords

  • antioxidant compounds
  • beneficial microbes
  • bioactive compounds
  • functional foods
  • gut microbiota
  • health benefits
  • postbiotics
  • prebiotics
  • probiotics
  • synbiotics
  • psychobiotics

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Published Papers (1 paper)

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Research

24 pages, 4101 KiB  
Article
Influence of Autochthonous Lactic Acid Bacteria Cultures on the Microbiota and Biogenic Amine Production in Medium-Ripened Artisan Goat Cheese
by Julia Mariano Caju de Oliveira, Adriane Elisabete Costa Antunes, Gustavo Felipe Correia Sales, Camila Neves Meireles Costa, Angela Matilde da Silva Alves, Kaíque Yago Gervazio de Lima, Celso José Bruno de Oliveira, Antônio Silvio do Egito, Karina Maria Olbrich dos Santos, Evandro Leite de Souza, Maria Teresa Bertoldo Pacheco and Maria Elieidy Gomes de Oliveira
Foods 2025, 14(9), 1561; https://doi.org/10.3390/foods14091561 - 29 Apr 2025
Viewed by 244
Abstract
This study evaluated the effects of adding the autochthonous cultures Limosilactobacillus mucosae CNPC007 (LM) and Lactiplantibacillus plantarum CNPC003 (LP), originally isolated from goat milk and goat cheese, respectively, on microbiological safety, microbiota composition (analyzed through 16S rRNA gene metataxonomic sequencing), and biogenic amine (BA) production [...] Read more.
This study evaluated the effects of adding the autochthonous cultures Limosilactobacillus mucosae CNPC007 (LM) and Lactiplantibacillus plantarum CNPC003 (LP), originally isolated from goat milk and goat cheese, respectively, on microbiological safety, microbiota composition (analyzed through 16S rRNA gene metataxonomic sequencing), and biogenic amine (BA) production in artisanal goat (coalho) cheese made from raw or pasteurized milk during 60 days of ripening at 10 °C. Six types of cheese were produced, varying in milk treatment (raw or pasteurized) and the presence or absence of LP or LM cultures. Adding either LP or LM significantly modulated the microbiota, favoring Streptococcus dominance and reducing overall bacterial diversity compared to non-inoculated cheeses. Raw milk cheeses with added autochthonous cultures exhibited a microbial profile like pasteurized cheeses, suggesting a homogenizing effect on the microbiome. Both cultures effectively reduced microbial load in raw milk cheeses after 20 days, reaching levels comparable to pasteurized cheeses by the end of ripening. Although BA concentrations increased over time, all samples remained within safe limits. Cheeses with LP addition exhibited lower BA levels, suggesting a modulating effect on their biosynthesis. Histamine concentrations were higher in raw milk cheeses with added cultures but remained well below hazardous levels. These findings suggest that incorporating either LP or LM strains is a promising strategy for enhancing the microbial safety and standardization of artisanal goat cheese while preserving its traditional characteristics. Full article
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