Unlocking the Potential of Ancient Grains: Health Benefits and Food Applications

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Grain".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 2096

Special Issue Editors


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Guest Editor
CREA—Research Centre for Engineering and Agro-Food Processing, Via Manziana, 30, 00189 Rome, Italy
Interests: wheat; minor cereals; cereal quality; gluten; gluten intolerances; gluten-free; pasta; cereals processing; bioactive compounds; functional foods; plant biotechnology; breeding for quality
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
CREA—Research Centre for Engineering and Agro-Food Processing, Via Manziana, 30, 00189 Rome, Italy
Interests: wheat; cereal quality; pasta; cereals processing; cereal technology; bioactive compounds; functional foods; malt; beer; cereal pathology; vegetable milks
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The need for agro-food biodiversity, as well as the contemporary consumer demand for traditional healthy foods, has driven renewed interest in ancient grains. Even though they have been around for centuries, old species and varieties of cereals and legumes have been widely promoted in recent years to exploit their nutritional, technological, sensorial and healthy (real or alleged) properties, taking into account their intrinsic cultural and historic value. Ancient species and varieties have unique genetic makeups compared to modern counterparts due to many years of adaptation to their original growing conditions, although their superior healthy properties remain a controversial issue due to the fragmentation of scientific knowledge. Ancient grains can represent a valuable source of income for supply-chain actors, such as farmers, food producers and retailers. In particular, the food industry has been attracted by these commodities and is investing in the production of innovative foods using these grains either as raw or functional ingredients. In this Special Issue, we will publish innovative research and review papers about the rediscovery of ancient grains; their technological, biochemical and nutritional characteristics; and tests of their suitability for use in innovative food products that meet the needs of health-conscious consumers to encourage the use of niche raw materials. New raw materials, new functional ingredients, up-cycling of waste materials, and in vivo experiments to test the effects of the consumption of these grains will be addressed in this Special Issue. Predictions of product quality, adopting chemometric, multi-variate and statistical data analysis approaches, are welcomed. Tools (e.g., focus groups, surveys, and semi-structured interviews) that help us to identify the factors that affect the adoption of ancient grains at different stages of the value chain, as well as identify opportunities for their expansion, will be further addressed in this Special Issue.

Dr. Laura Gazza
Dr. Francesca Nocente
Guest Editors

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Keywords

  • cereals
  • legumes
  • landraces
  • populations
  • associations
  • sustainability
  • agro-food biodiversity
  • healthy diets
  • agroecology
  • value chain

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Published Papers (2 papers)

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23 pages, 1965 KB  
Article
Effect of Different Disinfection Procedures on the Microbiological Quality and Germination Efficacy of Sprouted Quinoa (Chenopodium quinoa) Flour
by Silvia Melissa García-Torres, José António Teixeira, Christian R. Encina-Zelada, Cristina L. M. Silva and Ana Maria Gomes
Foods 2025, 14(18), 3196; https://doi.org/10.3390/foods14183196 - 13 Sep 2025
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Abstract
Grain processing requires sustainable and innovative alternatives. Germination, which enhances the nutritional value of grains, can also increase the microbial load, posing a challenge to food safety. In quinoa, a superfood with an exceptional nutritional profile, germination could maximize its benefits if proper [...] Read more.
Grain processing requires sustainable and innovative alternatives. Germination, which enhances the nutritional value of grains, can also increase the microbial load, posing a challenge to food safety. In quinoa, a superfood with an exceptional nutritional profile, germination could maximize its benefits if proper methods are applied to ensure safety. The effects of different disinfection methods on mesophilic aerobic bacteria, enterobacteria, and the germination capacity of two Peruvian quinoa varieties (Rosada de Huancayo (RH) and Pasankalla (PK)) were evaluated for germinated flour production. Seven treatments were applied: four with chemical agents (200 ppm sodium hypochlorite, 4% acetic acid, 8% H2O2, and 70% alcohol) and three combined methods (sodium hypochlorite with ultrasound (35 kHz, 15 or 30 min), and hot water (50 °C) with H2O2 (2%) and acetic acid (0.1%)). All treatments significantly reduced mesophilic aerobic bacteria (1.29–4.08 log CFU/g), except alcohol (PK, RH) and sodium hypochlorite (PK). Reductions in enterobacteria (p < 0.05) ranged from 1.78 to 3.55 log CFU/g in RH; in PK, only the hot water + 2 chemical agents or 8% H2O2 treatments achieved significant reductions. The most effective treatment was hot water with H2O2 and acetic acid, which reduced bacteria and improved germination. Full article
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27 pages, 1751 KB  
Systematic Review
Therapeutic Efficacy of Soy-Derived Bioactives: A Systematic Review of Nutritional Potency, Bioactive Therapeutics, and Clinical Biomarker Modulation
by Zara Fatima, Nizwa Itrat, Beenish Israr and Abdul Momin Rizwan Ahmad
Foods 2025, 14(19), 3447; https://doi.org/10.3390/foods14193447 - 9 Oct 2025
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Abstract
Soybeans (Glycine max) are nutrient-dense legumes and a high-quality plant-based protein source containing all essential amino acids. With a protein content of 36–40%, soy surpasses many other plant-derived proteins in nutritional value. Its bioactive components, particularly peptides and isoflavones, contribute to [...] Read more.
Soybeans (Glycine max) are nutrient-dense legumes and a high-quality plant-based protein source containing all essential amino acids. With a protein content of 36–40%, soy surpasses many other plant-derived proteins in nutritional value. Its bioactive components, particularly peptides and isoflavones, contribute to reducing inflammation, oxidative stress, and the risk of chronic diseases. In undernourished regions such as Pakistan, where protein-energy malnutrition is prevalent among women and children, soy offers a sustainable and cost-effective nutritional intervention. This review synthesizes findings from biochemical analyses, nutritional profiling, and clinical trials evaluating the impact of soybean protein and its bioactive compounds on growth, metabolic health, immune function, and disease prevention. Emphasis was placed on studies relevant to food-insecure populations and technological innovations enhancing soy product bioavailability. Soy protein has been shown to have positive effects on hormonal regulation, cardiovascular health, cognitive function, and immune support. Technological approaches such as fortification and fermentation improve nutritional bioavailability and sensory acceptance. The integration of soy into local diets enhanced nutritional adequacy, promoted environmental sustainability, and aligned with Sustainable Development Goals. Soybeans represent a sustainable, nutrient-rich solution to combat protein-energy malnutrition in vulnerable communities. Their high-quality protein profile, therapeutic properties, and adaptability to local food systems make them an effective strategy for improving public health and supporting environmental resilience. Full article
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