Sustainable Food Production from Waste and By-Products in the Food Industry

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Quality and Safety".

Deadline for manuscript submissions: 15 February 2026 | Viewed by 736

Special Issue Editors


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Guest Editor
State Key Laboratory of Food Science and Technology, Engineering Research Center for Biomass Conversion, Ministry of Education, Nanchang University, Nanchang, China
Interests: carbon materials; catalytic pyrolysis; value-added products; biodiesel production; hydrocarbon-rich fuel; nanoparticles; sustainable biorefinery; biohydrogen
Special Issues, Collections and Topics in MDPI journals
State Key Laboratory of Food Science and Technology, Engineering Research Center for Biomass Conversion, Ministry of Education, Nanchang University, Nanchang 330047, China
Interests: biomass waste; adsorbent materials; microalgae cultivation; anaerobic digestion; wastewater treatment; wine wastewater; resource recovery; bioproducts
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

With the acceleration of urbanization and upgrades to consumer demands, the scale of the food industry is continuing to expand, leading to a significant increase in the quantity of by-products and waste. The food industry is actively promoting the green, low-carbon, circular, and efficient development of the sector through the resourceful and high-value utilization of these by-products and waste. For instance, proteins and fibers are extracted from food by-products via enzymatic hydrolysis and fermentation to produce feed products with high nutritional value, such as plant-based meats and dairy alternatives. Additionally, high-value healthcare ingredients, including natural vitamin E, phytosterols, and squalene, are extracted from food by-products using advanced techniques such as esterification, urea adduction, enzymatic methods, molecular distillation, and ion exchange. Furthermore, food waste is being transformed into organic fertilizers through processes like high-temperature sterilization, composting, and anaerobic fermentation, which are subsequently used to cultivate high-quality food raw materials. This Special Issue aims to provide a platform for encouraging the development of new processes and the exploration of innovative mechanisms related to the high-value utilization of food by-products and waste. Original papers and reviews focusing on innovative research and technological advancements in this field are warmly welcomed for inclusion in this Special Issue.

Prof. Dr. Yunpu Wang
Dr. Qi Zhang
Dr. Shuhao Huo
Guest Editors

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Keywords

  • food by-products
  • food waste
  • high-value utilization
  • healthcare ingredients
  • high-quality food raw materials
  • organic fertilizers

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Published Papers (2 papers)

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Research

25 pages, 6538 KB  
Article
Dual Blockade of PI3K and EGFR Pathways by Flavonoids from Idesia polycarpa Maxim Cake Meal: Valorization of Agro-Industrial Waste for NSCLC Therapy
by Zhenyu Yang, Kai Luo, Dan Chen, Lei Dou, Xiufang Huang and Jianquan Kan
Foods 2025, 14(18), 3278; https://doi.org/10.3390/foods14183278 - 22 Sep 2025
Abstract
Efficient utilization of food industry waste supports sustainable development. Idesia polycarpa Maxim cake meal (an oil-processing by-product) is rich in bioactive flavonoids, but the refined purification, anti-non-small cell lung cancer (NSCLC) activity, and mechanism of its total flavonoids (IPTF) remain unclear—restricting high-value use. [...] Read more.
Efficient utilization of food industry waste supports sustainable development. Idesia polycarpa Maxim cake meal (an oil-processing by-product) is rich in bioactive flavonoids, but the refined purification, anti-non-small cell lung cancer (NSCLC) activity, and mechanism of its total flavonoids (IPTF) remain unclear—restricting high-value use. This study optimized IPTF purification via polyamide resin gradient elution and characterized its chemical composition by HPLC/LC-MS. In vitro assays assessed IPTF’s effects on A549 cell proliferation, migration, invasion, colony formation, and apoptosis; network pharmacology and molecular docking predicted mechanisms, validated via Western blotting for key signaling pathways. Results showed IPTF purity was significantly improved after purification; HPLC/LC-MS identified rutin, quercetin, and six minor components as key constituents. IPTF inhibited A549 proliferation, and network pharmacology indicated it synergistically targets the PI3K/AKT and EGFR-MAPK pathways—validated by reduced phosphorylation of p-AKT, p-EGFR, and p-ERK. This work offers a novel strategy for I. polycarpa cake meal valorization and highlights IPTF’s potential as a multi-target natural candidate for NSCLC therapy. Full article
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12 pages, 612 KB  
Article
Determination of the Quality of Oil Obtained from Protein Hydrolysate Produced Using Rainbow Trout (Oncorhynchus mykiss) By-Products
by Koray Korkmaz and Serpil Öztürk
Foods 2025, 14(18), 3227; https://doi.org/10.3390/foods14183227 - 17 Sep 2025
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Abstract
The growing demand for sustainable food sources requires the efficient use of aquaculture by-products. This study aimed to optimize enzymatic hydrolysis conditions for the simultaneous recovery of fish protein hydrolysate (FPH) and oil from rainbow trout (Oncorhynchus mykiss) processing by-products. Hydrolysis [...] Read more.
The growing demand for sustainable food sources requires the efficient use of aquaculture by-products. This study aimed to optimize enzymatic hydrolysis conditions for the simultaneous recovery of fish protein hydrolysate (FPH) and oil from rainbow trout (Oncorhynchus mykiss) processing by-products. Hydrolysis was performed at different temperatures (30–50 °C), enzyme concentrations (0.5–1.5%), and durations (30–90 min), and the optimal conditions were determined as 40 °C, 1% enzyme concentration, and 60 min. Under these conditions, oil yield reached 11.46%, while quality indices remained within acceptable limits (peroxide value: 1.78–3.47 meq O2/kg; thiobarbituric acid reactive substances: 0.41–1.41 mg MDA/kg; free fatty acids: 0.27–4.12%). Fatty acid analysis revealed 22.5% saturated, 46.31% monounsaturated, and 23.52% polyunsaturated fatty acids, including notable levels of EPA and DHA. The protein hydrolysates obtained under optimized conditions contained 22.61% protein and essential amino acids, accounting for 52.4% of the total amino acid content, confirming their high nutritional value. Overall, the findings demonstrate that rainbow trout by-products can be effectively valorized through enzymatic hydrolysis to produce oil and protein hydrolysates of acceptable quality, which may serve as alternative ingredients for food and feed applications. Full article
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