Emerging Technologies for the Extraction and Purification of Bioactive Compounds

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Engineering and Technology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 977

Special Issue Editors


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Guest Editor
URD Agro-Biotechnologies Industrielles, CEBB, AgroParisTech, 51110 Pomacle, France
Interests: extraction and purification process; valorization of agrofood industry byproducts; antioxidants; phenolic compounds; supercritical CO2 extraction; ultrasound-assisted extraction; microwave-assisted extraction; physical pretreatments; electrical pretreatments; liquid–liquid extraction; membrane filtration; adsorption

Special Issue Information

Dear Colleagues,

Our Special Issue on emerging technologies for the extraction and purification of bioactive compounds aims to highlight the latest advancements in this rapidly evolving field. We focus on innovative techniques that efficiently recover bioactive compounds while preserving their nutritional and functional properties.

Covered approaches include the following:

Supercritical fluid extraction (SFE): Utilizing supercritical CO2 to selectively extract bioactives without harmful solvents.

Ultrasound-assisted extraction (UAE): Enhancing solvent penetration and disrupting cell walls for improved yields.

Microwave-assisted extraction (MAE): Accelerating extraction with rapid microwave heating.

Enzyme-assisted extraction (EAE): Using enzymes to hydrolyze cell walls and release compounds.

High-voltage electrical discharge (HVED): Employing electrical discharges to disrupt cell walls and enhance extraction.

Pulsed electric field (PEF): Permeabilizing cell membranes with high-voltage implusions to extract bioactives.

Topics include extraction and optimization strategies, purification methods, applications in functional foods, and sustainability considerations. We invite researchers and scientists from academia and industry to share original research, reviews, and perspectives. By fostering collaboration and knowledge exchange, we aim to advance our understanding of these technologies and their impact on food science and nutrition.

Join us in exploring bioactive compound extraction and purification for healthier, sustainable, and more functional food products.

Dr. Morad Chadni
Prof. Dr. Nabil Grimi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • extraction technologies
  • purification process
  • bioactive compounds
  • food byproducts
  • biomass valorization
  • emerging technologies
  • pretreatments

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Published Papers (1 paper)

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Research

18 pages, 3764 KiB  
Article
Green Extraction Methods Applied to the Brown Macroalga Saccharina latissima: Assessing Yield, Total Phenolics, Phlorotannins and Antioxidant Capacity
by Jonas da Silva, Luana Cristina dos Santos, Elena Ibañez and Sandra Regina Salvador Ferreira
Foods 2025, 14(6), 1017; https://doi.org/10.3390/foods14061017 - 17 Mar 2025
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Abstract
The brown seaweed Saccharina latissima is an abundant, although yet underutilized, source of natural bioactive compounds commonly found in western regions. In recent years, brown algae have garnered attention as promising sources of polyphenols, particularly phlorotannins. The recovery of these relevant components by [...] Read more.
The brown seaweed Saccharina latissima is an abundant, although yet underutilized, source of natural bioactive compounds commonly found in western regions. In recent years, brown algae have garnered attention as promising sources of polyphenols, particularly phlorotannins. The recovery of these relevant components by eco-friendly and energy-efficient methods with solvents GRAS (Generally recognized as safe) contributes to minimizing environmental impact, and promotes sustainability. Pressurized liquid extraction (PLE) and microwave-assisted extraction (MAE) optimized by Box–Behnken design (BBD) were explored for this purpose. The methods were evaluated considering the process yield and the quality of the recovered extracts by phenolic and phlorotannin levels, and their antioxidant capacity was assessed by DPPH and ABTS assays. The optimized MAE techniques (80 °C, 2% EtOH/Water at 40 mL g−1) and PLE2 (80 °C with water) showed the highest extract yields, with increases of 65.76% and 37.36%, respectively, compared to CRE. PLE2 also achieved higher TPC and antioxidant capacity (ABTS) values by 61.88% and 80.39%, respectively. MAE (optimized) increased TPC and ABTS by 53.90% and 36.42%, respectively. Regression analysis of MAE confirmed the accuracy of the models in assessing interaction parameters (adjustment p < 0.05 and adequacy R2 > 0.86). Therefore, the study presents eco-efficient approaches for recovering phenolic compounds and antioxidants from brown algae, contributing to the valorization of these resources in the industry and enhancing their application. Full article
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