Probiotics and Prebiotics in Food: Advances and Latest Trends

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Microbiology".

Deadline for manuscript submissions: closed (31 May 2026) | Viewed by 2934

Special Issue Editors


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Guest Editor
Department of Food Gastronomy and Food Hygiene, Warsaw University of Life Sciences, Nowoursynowska Str. 159C, 02-776 Warsaw, Poland
Interests: food safety and quality; food fermentation; in vitro digestion; food product development
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (WULS), Nowoursynowska St. 159C, 02-776 Warszawa, Poland
Interests: probiotics; lactic acid baceria; acetic acid bacteria; fermentation; kombucha

E-Mail Website
Guest Editor
Department of Food Gastronomy and Food Hygiene, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences, Nowoursynowska 159C St., 02-776 Warsaw, Poland
Interests: food safety; bacteriocins; lactic acid bacteria; human microbiome; probiotic microorganisms; probiotic food development
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Probiotics and prebiotics are advancing rapidly, driven by scientific breakthroughs and consumer demand for holistic wellness solutions. Referring to probiotics, the latest trends are research on precision probiotics. The industry is shifting towards personalized formulations based on individual microbiome profiles, offering targeted health benefits. Moreover, postbiotics, i.e., the bioactive compounds produced by probiotics, and synbiotics (prebiotics + probiotics) are gaining traction for their enhanced health benefits. Finally, brands must focus on scientific validation and transparent labeling to meet regulatory standards. In the area of prebiotics, there is a growing emphasis on prebiotic fiber intake due to its role in supporting overall well-being through the gut microbiome. Also, the gut–brain axis is extensively researched to support mental health benefits alongside gut health. Considering future directions in the research and development of biotics in food, much attention is given to personalized nutrition because the advances in microbiome analysis are enabling tailored nutritional strategies that address unique health needs.

Therefore, the aim of this Special Issue, titled “Probiotics and Prebiotics in Food: The Advances and Latest Trends”, is to explore the current landscape and recent developments in the field of biotics, covering health, microbiome, and technological aspects.

We are pleased to invite you to participate in our Special Issue, thereby increasing the reach of global research on biotics, their impact on health, and their technological usefulness. In this Special Issue, original research articles and reviews are welcome.

The presented Special Issue has roots in the Polish Scientific Symposium on Probiotics and Prebiotics in Food. This symposium has been organized annually for 15 years and brings together the best Polish and international specialists in biotics.

We look forward to receiving your contributions,

Dr. Monika Trząskowska
Dr. Katarzyna Neffe-Skocińska
Dr. Dorota Zielińska
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biotics
  • probiotics
  • prebiotics
  • postbiotics
  • synbiotics
  • food
  • microbiota
  • fiber
  • precision nutrition
  • precision probiotics

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Published Papers (1 paper)

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Research

15 pages, 704 KB  
Article
Dual-Strain Psychobiotics Combining Live Lactiplantibacillus plantarum PS128 and Heat-Treated Lacticaseibacillus paracasei PS23 Improve Psychological and Neuroendocrine Outcomes in Stressed Adults: A Randomized, Placebo-Controlled Trial
by Mon-Chien Lee, Ting-An Lin and Chi-Chang Huang
Foods 2025, 14(24), 4190; https://doi.org/10.3390/foods14244190 - 6 Dec 2025
Cited by 1 | Viewed by 2413
Abstract
Chronic psychological stress impairs neuroendocrine balance and increases the risk of mental health disturbances, including anxiety, sleep disruption, and low mood. The gut–brain axis has emerged as a promising target for stress modulation, particularly through psychobiotic interventions. This randomized, double-blind, placebo-controlled trial evaluated [...] Read more.
Chronic psychological stress impairs neuroendocrine balance and increases the risk of mental health disturbances, including anxiety, sleep disruption, and low mood. The gut–brain axis has emerged as a promising target for stress modulation, particularly through psychobiotic interventions. This randomized, double-blind, placebo-controlled trial evaluated the effects of a combined psychobiotic formulation (Neuralli Mood), comprising live Lactiplantibacillus plantarum PS128 (PS128) and heat-treated Lacticaseibacillus paracasei PS23 (HT-PS23), on the psychological and physiological stress responses in a high-stress occupational population. A total of 116 healthy participants with elevated perceived stress (PSS ≥ 14), primarily firefighters, were randomly assigned to receive the dual-strain supplement or placebo for 8 weeks. Stress-related outcomes were assessed by using validated psychological scales and serum biomarkers. Compared with placebo, the psychobiotics group showed significantly greater reductions in overall job stress perception (JSS), state anxiety (STAI), and insomnia severity (ISI) (all p < 0.05). Additionally, serum adrenocorticotropic hormone (ACTH) and norepinephrine levels were significantly reduced post-intervention, whereas cortisol levels remained unchanged. These findings suggested that combining live and heat-treated psychobiotic strains may provide a safe and effective strategy for alleviating psychological stress and regulating neuroendocrine function in high-risk populations. Full article
(This article belongs to the Special Issue Probiotics and Prebiotics in Food: Advances and Latest Trends)
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