Improving Food Quality and Safety: An Exploration of Natural Antimicrobials

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Quality and Safety".

Deadline for manuscript submissions: 10 June 2025 | Viewed by 701

Special Issue Editors


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Guest Editor
Departamento de Ciência de Alimentos, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
Interests: bioactive compounds; natural antimicrobials; nanotechnology; food safety; food microbiology; encapsulation; active packaging
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Department of Environmental Health Sciences, College of Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates
2. Laboratory of Food Chemistry and Food Microbiology, Department of Chemistry, University of Ioannina, 451 10 Ioannina, Greece
Interests: food safety; natural food antimicrobials; food quality and safety of traditional Mediterranean and Arabic foods
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The growing demand for minimally processed foods and the use of natural ingredients instead of synthetic additives are shaping the preferences of consumers worldwide. In this context, natural antimicrobials have emerged as a promising alternative, enhancing the quality and safety of food while meeting the needs of a more conscious and sustainable market.

Natural antimicrobials include bioactive compounds derived from plants, such as the phenolics and terpenes found in herbs, spices, and essential oils, as well as substances of animal origin, such as antimicrobial peptides and chitosan. These antimicrobials can be applied directly in the formulation of food products as preservation agents, aiding in the prevention of spoilage and the growth of pathogens and fungi that compromise the quality and safety of food, thereby extending its shelf life.

This Special Issue aims to compile research articles and literature reviews concerning the application of natural antimicrobials as food additives, highlighting their impact on the quality and safety of food. We welcome submissions that address aspects such as sources and extraction methods, antimicrobial efficacy, viability in different food matrices, as well as the challenges associated with the use of natural antimicrobials in the food industry.

Dr. Patrícia Da Silva Malheiros
Prof. Dr. Ioannis Savvaidis
Guest Editors

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Keywords

  • natural preservatives
  • natural antimicrobials
  • bioactive compounds
  • essential oils
  • bacteriocins
  • food safety
  • food quality
  • nanotechnology
  • encapsulation
  • preservation strategies

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Published Papers (1 paper)

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Research

17 pages, 4128 KiB  
Article
Phenotypic and Genomic Insights into Schleiferilactobacillus harbinensis WU01, a Candidate Probiotic with Broad-Spectrum Antimicrobial Activity Against ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter) Pathogens
by Chonticha Romyasamit, Komwit Surachat, Nawanwat C. Pattaranggoon, Pinkanok Suksabay, Uttapol Permpoon, Tae-Gyu Nam and Phoomjai Sornsenee
Foods 2025, 14(7), 1161; https://doi.org/10.3390/foods14071161 - 27 Mar 2025
Viewed by 527
Abstract
The increasing prevalence of multidrug-resistant (MDR) pathogens, particularly ESKAPE bacteria, necessitates alternative antimicrobial strategies. Probiotics, particularly lactic acid bacteria, protect against pathogenic infections. This study aimed to characterize Schleiferilactobacillus harbinensis WU01, isolated from fermented palm sap, and evaluate its probiotic potential and antimicrobial [...] Read more.
The increasing prevalence of multidrug-resistant (MDR) pathogens, particularly ESKAPE bacteria, necessitates alternative antimicrobial strategies. Probiotics, particularly lactic acid bacteria, protect against pathogenic infections. This study aimed to characterize Schleiferilactobacillus harbinensis WU01, isolated from fermented palm sap, and evaluate its probiotic potential and antimicrobial activity. Its probiotic characteristics were assessed based on low-pH and bile tolerance, auto-aggregation, hydrophobicity, and adhesion to Caco-2 cells. Antimicrobial activity against ESKAPE pathogens was evaluated using the agar well diffusion assay. Whole-genome sequencing (WGS) and in silico analysis were performed to identify bacteriocin-related genes, virulence factors, and antibiotic-resistance genes. WU01 exhibited a strong tolerance to gastrointestinal conditions, with high survival rates under acidic and bile-salt environments. S. harbinensis WU01 demonstrated significant auto-aggregation, high hydrophobicity, and strong adhesion to Caco-2 cells. Antimicrobial assays revealed inhibitory activity against MDR ESKAPE pathogens, which correlated with the presence of bacteriocin-related genes, including those homologous to Carnocin_CP52. Molecular dynamics (MDs) simulations confirmed the interaction of Carnocin_CP52 with bacterial membranes, suggesting a mechanism for pathogen disruption. WGS confirmed the absence of virulence and antimicrobial-resistance genes, confirming its safety for probiotic applications. These findings suggest that S. harbinensis WU01 possesses probiotic properties and antimicrobial activity against ESKAPE pathogens. The combined results highlight its potential application in functional foods and therapeutic interventions. Full article
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