Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Machine-Learning-Based Disease Diagnosis and Prediction
edited by Fakhar Abbas
submission deadline 30 Sep 2025 | 17 articles | Viewed by 26786 | Submission Open
Keywords: development and validation of machine learning models for disease diagnosis and prediction; integration of multimodal data (e.g.; imaging; genomic; and clinical) for enhanced diagnostic accuracy; artificial intelligence in healthcare; ethical and regulatory considerations in the deployment of machine learning for healthcare applications; case studies and applications of machine learning in specific disease domains (e.g.; cancer; cardiovascular diseases; and neurodegenerative disorders); comparative studies and benchmarking of machine learning approaches for disease diagnosis and prediction; healthcare analytics; bioinformatics; medical imaging analysis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Deep Learning in Medical and Biomedical Image Processing
edited by
submission deadline 30 Sep 2025 | 8 articles | Viewed by 25754 | Submission Open
Keywords: deep learning; medical and biomedical image processing; model explainability and evaluation; generative model; machine learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
The Future of Diagnostics: Exploring the Role of Artificial Intelligence in Medicine
edited by , Neil Vaughan and Jiaxiang Zhang
submission deadline 30 Sep 2025 | 4 articles | Viewed by 9249 | Submission Open
Keywords: diagnostics; artificial intelligence; medicine; healthcare; future
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in the Diagnostics of Dental Diseases, 2nd Edition
edited by Hakan Turkkahraman
submission deadline 30 Sep 2025 | 4 articles | Viewed by 5822 | Submission Open
Keywords: artificial intelligence; machine learning; neural networks; dental diseases; clinical decision support systems; medical diagnosis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence Application in Cornea and External Diseases submission deadline 30 Sep 2025 | 3 articles | Viewed by 5075 | Submission Open
Keywords: artificial intelligence; machine learning; cornea; ocular surface; ophthalmology; external eye diseases; mobile health; telemedicine
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Integrative Approaches in Head and Neck Cancer Imaging
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3594 | Submission Open
Keywords: head and neck cancer; imaging technologies; multimodal imaging; image-guided therapy; artificial intelligence in imaging
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in the Use of Artificial Intelligence for the Diagnosis and Management of Hand Conditions
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1435 | Submission Open
Keywords: artificial intelligence; machine learning; hand conditions; preoperative diagnosis; postoperative prognosis; surgical outcomes; imaging techniques
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Classification of Diseases Using Machine Learning Algorithms: 2nd Edition
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1281 | Submission Open
Keywords: artificial intelligence; classification of diseases; machine learning; medical image processing; deep learning; neural network; decision support systems
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Deep Learning and Multimodal Large Language Models in Tumor/Cancer Diagnosis, Prediction and Prognosis submission deadline 30 Sep 2025 | 1 articles | Viewed by 701 | Submission Open
Keywords: diagnosis; prognosis; tumor/cancer; deep learning; multimodal large language models
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Alzheimer’s Disease Diagnosis—2nd Edition submission deadline 30 Sep 2025 | Viewed by 459 | Submission Open
Keywords: Alzheimer’ s disease; artificial intelligence; machine learning; explainable AI; expert systems; computer vision; deep learning; diagnosis; cognition; brain informatics; neurodegenerative disorder
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Biomedical Signal and Imaging Processing submission deadline 30 Sep 2025 | Viewed by 297 | Submission Open
Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Diagnosis of Sleep Disorders Using Machine Learning Approaches, 2nd Edition
edited by , Shyam Subramanian and
submission deadline 30 Sep 2025 | Viewed by 246 | Submission Open
Keywords: diagnosis; screening; marker; prognosis; sleep disorders; machine learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Radiation Oncology
edited by Xianjin Dai
submission deadline 30 Sep 2025 | Viewed by 167 | Submission Open
Keywords: artificial intelligence in radiation therapy; deep learning-based auto-segmentation; AI-driven radiotherapy; treatment planning; adaptive radiation therapy with AI radiomics and machine learning for outcome prediction; multi-modal image analysis in radiotherapy; reinforcement learning for dose optimization uncertainty; quantification in AI for radiation oncology; trustworthy and explainable AI in cancer treatment; AI-integrated radiotherapy; workflow automation
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Deep Learning and Multimodal Feature Fusion for Advanced Medical Imaging Diagnosis submission deadline 30 Oct 2025 | 1 articles | Viewed by 923 | Submission Open
Keywords: deep learning; feature fusion; medical imaging; artificial intelligence in healthcare; diagnostic imaging; multimodal data integration; explainable AI; clinical decision support
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Deep Learning in Medical Imaging: Challenges and Opportunities
edited by Morten Bo Søndergaard Svendsen
submission deadline 30 Oct 2025 | Viewed by 264 | Submission Open
Keywords: deep learning; artificial intelligence; medical imaging; endoscopy; image segmentation; medical image processing
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Machine Learning for Computer-Aided Diagnosis in Biomedical Imaging—2nd Edition
edited by
submission deadline 31 Oct 2025 | 14 articles | Viewed by 26884 | Submission Open
Keywords: cancer diagnosis; medical images; electronic health records; machine learning; deep learning; artificial intelligence; explainable AI models; multi-modal analysis; federated learning; CAD systems
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Deep Learning in Medical Image Segmentation and Diagnosis
edited by Rahib Abiyev
submission deadline 31 Oct 2025 | 11 articles | Viewed by 24690 | Submission Open
Keywords: deep learning in medical diagnosis; medical imaging and deep learning; data mining and deep learning; emerging deep learning techniques and diagnosis; deep learning for the classification of lesions and disease; deep learning for segmentation; denoising; and super resolution; deep learning for signal analysis; learning mechanisms in deep neural networks; ensemble learning; stacked networks; medical informatics; computer-assisted diagnosis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
A New Era in Diagnosis: From Biomarkers to Artificial Intelligence submission deadline 31 Oct 2025 | 11 articles | Viewed by 16413 | Submission Open
Keywords: diagnosis; precision medicine; predictive diagnostics; therapeutic strategies; biomarkers; artificial intelligence; machine learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advancements in Artificial Intelligence for Dentomaxillofacial Radiology—2nd Edition submission deadline 31 Oct 2025 | 7 articles | Viewed by 10948 | Submission Open
Keywords: artificial intelligence; deep learning; dentomaxillofacial radiology; dentistry; diagnosis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Clinical Decision Support—2nd Edition
edited by
submission deadline 31 Oct 2025 | 4 articles | Viewed by 5270 | Submission Open
Keywords: artificial intelligence; machine learning; clinical decision support; predictive modeling; patient monitoring; diagnostic support; treatment recommendation; safety and privacy
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Generative AI and Deep Learning in Medical Diagnostics submission deadline 31 Oct 2025 | 1 articles | Viewed by 4347 | Submission Open
Keywords: generative AI; medical diagnostics; medical imaging processing and analysis; deep learning; machine learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Machine Learning for Medical Image Processing and Analysis
edited by Wei Shao
submission deadline 31 Oct 2025 | 3 articles | Viewed by 4047 | Submission Open
Keywords: machine learning; medical image processing; diagnostic accuracy; healthcare; algorithms
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
3rd Edition: AI/ML-Based Medical Image Processing and Analysis
edited by and Jaafar Alghazo
submission deadline 31 Oct 2025 | 4 articles | Viewed by 2646 | Submission Open
Keywords: machine learning; artificial intelligence; medical imaging; medical diagnosis; medical; magnetic resonance imaging (MRI); CT scan; X-ray; computer tomography; imaging techniques; medical conditions; convolutional neural networks; deep learning; transfer learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
AI-Powered Clinical Diagnosis and Decision-Support Systems
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2262 | Submission Open
Keywords: artificial intelligence; clinical decision support system; medical diagnostics
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Applications of Artificial Intelligence in Orthopedics
edited by Zhonghai Li
submission deadline 31 Oct 2025 | 1 articles | Viewed by 663 | Submission Open
Keywords: artificial intelligence; orthopedics; medical diagnosis; image analysis; predictive modeling
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
The Role of AI and Radiomics in Diagnostic Oncology
edited by Laura Travascio and
submission deadline 31 Oct 2025 | Viewed by 130 | Submission Open
Keywords: artificial intelligence; pathophysiological; radiology and nuclear medicine; diagnostic imaging; diagnostic oncology
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Computer-Aided Diagnosis in Endoscopy 2025
edited by
submission deadline 10 Nov 2025 | 1 articles | Viewed by 1043 | Submission Open
Keywords: AI; deep learning; endoscopy; machine learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence and Pattern Recognition Methods for the Automatic Detection and Evaluation of Neurological Disorders, 2nd Edition submission deadline 30 Nov 2025 | 6 articles | Viewed by 10113 | Submission Open
Keywords: machine learning; neurodegenerative diseases; diagnosis; detection and evaluation; monitoring
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence for Health and Medicine
edited by
submission deadline 30 Nov 2025 | 13 articles | Viewed by 9139 | Submission Open
Keywords: artificial intelligence; deep learning; healthcare; image segmentation; disease prediction; monitoring
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Application of Artificial Intelligence to Advance Individualized Diagnosis and Treatment in Emergency and Critical Care Medicine, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4921 | Submission Open
Keywords: critical care; sepsis; artificial intelligence; predictive analytics; clustering; acute kidney injury; emergency medicine; transcriptome
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Medical Images Segmentation and Diagnosis submission deadline 30 Nov 2025 | 2 articles | Viewed by 2539 | Submission Open
Keywords: medical images; segmentation; diagnosis; prognosis; AI
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Explainable Machine Learning in Clinical Diagnostics
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 1756 | Submission Open
Keywords: interpretable machine learning (IML); explainable machine learning; clinical medicine; knowledge integration; global/local explanations
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Application of Artificial Intelligence to Oral Diseases
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1571 | Submission Open
Keywords: oral disease; artificial intelligence; AI-driven diagnosis; oral radiology; cone beam computed tomography (CBCT)
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Physiological Sound Processing for Medical Diagnostics: Innovations, Challenges, and Applications
edited by and Prabal Datta Barua
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1449 | Submission Open
Keywords: heart sounds; lung sounds; cough analysis; sleep apnea and snoring; wearable devices; explainability and ethical AI; standardization and clinical validation
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
AI-Powered Solutions for Personalized Healthcare Monitoring with Wearables
edited by Kuo-Chung Chu, and Ming-Chun Huang
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1346 | Submission Open
Keywords: artificial intelligence; wearable technology; health monitoring; remote patient care; personalized healthcare
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Digital Innovation in Salivary Diagnostics for Oral and Systemic Health submission deadline 30 Nov 2025 | 1 articles | Viewed by 426 | Submission Open
Keywords: saliva diagnosis; oral disease; systemic diseases; artificial intelligence; AI driven diagnosis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Hearing Diseases
edited by
submission deadline 30 Nov 2025 | Viewed by 112 | Submission Open
Keywords: artificial intelligence; hearing loss; diagnosis; machine learning; auditory neuroscience; speech recognition; cochlear implants; data science; computational algorithm
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Artificial Intelligence in Healthcare submission deadline 31 Dec 2025 | 8 articles | Viewed by 18606 | Submission Open
Keywords: artificial intelligence; AI-driven radiomics; healthcare; digital radiology; precision medicine
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Pathological Image Analysis—2nd Edition
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 14171 | Submission Open
Keywords: histopathology; cytopathology; molecular pathology; surgical pathology; digital pathology; microscopy; whole slide image (WSI); clinical data; computer vision; deep learning; machine learning; computation; mathematics; domain adaptation; segmentation; classification; pattern recognition; explainable AI; reconstruction
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence Advances for Medical Computer-Aided Diagnosis—2nd Edition submission deadline 31 Dec 2025 | 6 articles | Viewed by 12640 | Submission Open
Keywords: image classification; image segmentation; medical image processing; biomedical optical imaging; medical signal processing; artificial intelligence; deep learning; machine learning; computer-aided diagnosis; explainable artificial intelligence
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence for Clinical Diagnostic Decision Making submission deadline 31 Dec 2025 | 4 articles | Viewed by 10039 | Submission Open
Keywords: artificial intelligence; machine learning; clinical decision support systems; health disparity; medical imaging; disease diagnosis; medical errors; patient safety
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
The Role of AI in Ultrasound
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 9409 | Submission Open
Keywords: artificial intelligence; medical ultrasound; diagnostic imaging; automated image interpretation; predictive modeling; personalized medicine; clinical workflow optimization; healthcare access; multidisciplinary innovation
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Dermatology
edited by Choon Chiat Oh
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4690 | Submission Open
Keywords: dermatology; artificial intelligence; deep learning; skin cancers; diagnostic imaging
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
The Applications of Radiomics in Precision Diagnosis
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2018 | Submission Open
Keywords: artificial intelligence in precision diagnosis; disease classification; early diagnosis; imaging biomarkers; radiomics
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
AI in Radiology and Nuclear Medicine: Challenges and Opportunities
edited by Ioannis M. Tsougos
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1984 | Submission Open
Keywords: diagnosis; prognosis; radiology; nuclear medicine; artificial intelligence (AI)
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
New Technologies and Tools Used for Risk Assessment of Diseases
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1623 | Submission Open
Keywords: digital health; AI in healthcare; machine learning; disease risk prediction; medical imaging; wearable technology; big data analytics; telemedicine; personalized medicine; explainable AI
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Pathological Speech Classification and Processing for Advanced Medical Diagnosis submission deadline 31 Dec 2025 | 1 articles | Viewed by 1389 | Submission Open
Keywords: pathological speech; medical diagnosis; classification and processing; Parkinson's disease; hypokinetic dysarthria; dysarthria; aphasia; voice disorders; dysphonia; AI
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Gastrointestinal Disease: Diagnosis and Management in 2025
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 513 | Submission Open
Keywords: gastrointestinal disease; artificial intelligence; gastrointestinal cancer; inflammatory bowel disease; endoscopic AI; large language models
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Disease Prediction
edited by , Osman Hayran and Chalong Cheewakriangkrai
submission deadline 31 Jan 2026 | 5 articles | Viewed by 10027 | Submission Open
Keywords: early diagnostics; medical big data analytics; intelligent diagnostic models in public health; survival analysis and health hazard evaluations; machine learning and generative intelligence; intelligent digital twins; automated/intelligent laboratory recommendation systems
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
AI-Assisted Diagnostics in Telemedicine and Digital Health
edited by
submission deadline 31 Jan 2026 | 4 articles | Viewed by 9093 | Submission Open
Keywords: AI; machine learning; deep learning; image analysis; digital health; healthcare; telemedicine; disease diagnosis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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