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Dentistry Journal
Special Issues
Bone Regeneration and Tissue Reconstruction in Dentistry
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Bone Regeneration and Tissue Reconstruction in Dentistry

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: 30 September 2025 | Viewed by 4280

Special Issue Editor

Dr. Juho Suojanen

E-Mail Website
Guest Editor
1. Päijät-Häme Joint Authority for Health and Wellbeing, Department of Oral and Maxillofacial Surgery, Central Hospital, 15850 Lahti, Finland
2. Clinicum, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland
3. Cleft Palate and Craniofacial Center, Department of Plastic Surgery, HUS Helsinki University Hospital and University of Helsinki, 00029 Helsinki, Finland
Interests: maxillo-facial surgery; orthognathic surgery; virtual surgical planning; deformity surgery; CAD-CAM; patient-specific implants; medical modeling; facial trauma

Special Issue Information

Dear Colleagues,

Oral and maxillo-facial deformities, trauma, and various diseases can lead to impaired function and facial aesthetics. Long-lasting and functional reconstructions of facial structures often require a multidisciplinary approach and, sometimes, various operations with a focus on both bone and soft tissue reconstruction. Virtual surgical planning and medical modeling assistance through collaborations among all specialties in the field of dentistry represent everyday practice in most offices. Additionally, the development of bone and soft tissue substitutes and alloplastic materials, as well as surgical techniques, are rendering the reconstruction toolkit more and more versatile. However, a proper understanding of the basics of tissue reconstruction, deformity surgery, and a combination of surgical, periodontal, and prosthodontic techniques is essential and should be based on scientific background knowledge.

We welcome submissions of papers addressing the topics listed above for this Special Issue, including in vitro and animal models, clinical studies, epidemiological surveys, clinical trials, reviews, and meta-analyses. The Special Issue will focus on novel technigues such as additive manufacturing. It will also feature reports on novel materials and novel imaging and modeling techniques.

Dr. Juho Suojanen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bone grafting
  • bone substitutes
  • soft tissue regeneration
  • orthognathic surgery
  • virtual surgical planning
  • deformity surgery
  • CAD-CAM structures
  • patient-specific implants
  • additive manufacturing
  • implantology

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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13 pages, 3200 KiB  
Article
Socket Sealing Using Free Gingival Grafts: A Randomized Controlled Trial
by Ralitsa Yotsova
Dent. J. 2025, 13(1), 24; https://doi.org/10.3390/dj13010024 - 7 Jan 2025
Cited by 1 | Viewed by 892
Abstract
Background: Post-extraction ridge resorption is an inevitable phenomenon that cannot be eliminated but is significantly reduced using additional surgical techniques known as socket preservation. They aim to create favorable conditions for implant placement and prosthetic restoration. This study aims to assess the effect [...] Read more.
Background: Post-extraction ridge resorption is an inevitable phenomenon that cannot be eliminated but is significantly reduced using additional surgical techniques known as socket preservation. They aim to create favorable conditions for implant placement and prosthetic restoration. This study aims to assess the effect of socket sealing (SS) with free gingival grafts on the vertical resorption of socket walls at the premolar and molar regions over 3 months. Methods: This randomized two-arm controlled trial with parallel groups (1:1 allocation) was conducted at the Department of Oral Surgery, Medical University-Varna, Bulgaria, from 27 June 2022 to 20 April 2023. Forty patients aged 30–65 were equally and randomly allocated to the SS or the control groups. Atraumatic tooth extraction was performed. In the control group, the socket was left on secondary wound healing. In the SS group, the socket orifice was “sealed” with an FGG harvested from the hard palate or maxillary tuberosity. Results: Data analysis demonstrated that SS with an FGG is a successful method for reducing the post-extraction resorption of the socket walls. In addition, this study confirms that the thickness of the buccal wall is a significant factor in its vertical resorption. Conclusions: Socket sealing with an FGG is a valuable method that eliminates the need for flap reflection and compensates for the soft tissue deficit when immediate implant placement or bone augmentation is required. Further research is necessary to determine the role of different factors influencing bone resorption and compare the effect of different socket preservation methods. Full article
(This article belongs to the Special Issue Bone Regeneration and Tissue Reconstruction in Dentistry)
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13 pages, 1522 KiB  
Systematic Review
Hyaluronic Acid in Bone Regeneration: Systematic Review and Meta-Analysis
by Claudia Lorenzi, Andrea Leggeri, Ilaria Cammarota, Paolo Carosi, Vincenzo Mazzetti and Claudio Arcuri
Dent. J. 2024, 12(8), 263; https://doi.org/10.3390/dj12080263 - 19 Aug 2024
Cited by 4 | Viewed by 2934
Abstract
Aim: The aim of this systematic review and meta-analysis was to assess possible histomorphometric differences in new bone formation and in remaining graft particles when hyaluronic acid (HA) was added and mixed with graft materials in bone regeneration. Materials and methods: This review [...] Read more.
Aim: The aim of this systematic review and meta-analysis was to assess possible histomorphometric differences in new bone formation and in remaining graft particles when hyaluronic acid (HA) was added and mixed with graft materials in bone regeneration. Materials and methods: This review was registered at the International Prospective Register of Systematic Reviews (PROSPERO) of the National Institute of Health Research (registration number CRD42024530030). Electronic research was performed, and involved studies published up to 29 February 2024 using a specific word combination. The primary outcome was to assess possible histomorphometric differences in new bone formation and in remaining graft particles when HA was added and mixed with graft materials in bone regeneration. The search resulted in 138 potential studies. Meta-analyses were performed using the fixed and random effects model to identify significant changes in new bone formation and in the remaining graft particles. Results: After screening procedures, only three randomized controlled trials fulfilled the inclusion criteria and were selected for qualitative and quantitative analysis. The effect size of HA in the new bone formation was not statistically significant at 95% CI (Z = 1.734, p-value = 0.083, 95 % CI -,399; 6516). The effect size of HA in the remaining graft particles was not statistically significant at 95% CI (Z = −1.042, p-value = 0.297, CI -,835; 255). Conclusions: Within the limitations of the present systematic review and meta-analysis, the addition of HA to bone graft did not result in significant changes in bone regeneration procedures in terms of new bone formation and residues, even if the included studies showed encouraging and promising results. Full article
(This article belongs to the Special Issue Bone Regeneration and Tissue Reconstruction in Dentistry)
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