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Current Oncology
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Interventions to Prevent and Reduce Late Effects in Childhood, Adolescent,...
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Interventions to Prevent and Reduce Late Effects in Childhood, Adolescent, and Young Adult Cancer Survivors

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Childhood, Adolescent and Young Adult Oncology".

Deadline for manuscript submissions: 25 August 2025 | Viewed by 2976

Special Issue Editors

Prof. Dr. Katrin Scheinemann

E-Mail Website
Guest Editor
Division of Hematology/Oncology, Children’s Hospital of Eastern Switzerland, 9006 St. Gallen, Switzerland
Interests: survivorship; long-term follow-up care; neurooncology; AYA oncology
Special Issues, Collections and Topics in MDPI journals
Dr. Maria Otth

E-Mail Website
Guest Editor
1. Division of Hematology/Oncology, Children’s Hospital of Eastern Switzerland, St. Gallen, Switzerland
2. Department of Oncology, University Children’s Hospital Zurich, 8032 Zurich, Switzerland
Interests: survivorship; long-term follow-up care; AYA oncology; oncopolicy

Special Issue Information

Dear Colleagues,

We kindly invite medical professionals and researchers working in the field of pediatric, adolescent, and young adult oncology and focusing on survivorship care to submit their manuscripts to “Interventions to Prevent and Reduce Late Effects in Childhood, Adolescent, and Young Adult Cancer Survivors”, a Special Issue of Current Oncology.

It is well known that the cancer itself and its treatment can cause chronic medical problems in children, adolescents, and young adults. These late effects can affect the cardiovascular system, endocrine system, osteoporosis, obesity, or psychological aspects. Interventions have the potential to prevent, reduce, or improve existing chronic medical conditions (e.g., cardiovascular disease, osteoporosis, neurocognition) in the general population. Some data also exist for childhood, adolescent, and young adult cancer survivors. Many interventions are currently studied in different settings (inpatient, outpatient, combined), at different time points (during treatment, after treatment), and with different aims (mental health, concentration, physical health).

This Special Issue offers the opportunity to bring together articles that explore interventions to prevent, reduce, or reverse late effects in childhood, adolescent, and young adult cancer patients and survivors.

Prof. Dr. Katrin Scheinemann
Dr. Maria Otth
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • intervention
  • childhood cancer
  • adolescents and young adults (AYA)
  • physical activity
  • neurocognition
  • mental health
  • quality of life
  • late effects

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Research

13 pages, 458 KiB  
Article
Parental Reports on Late Effects and Follow-Up Needs: A Single-Center Assessment of Childhood Cancer Survivorship Care in Kenya
by Susan Nyabate Mageto, Jesse P. M. Lemmen, Festus Muigai Njuguna, Nancy Midiwo, Sandra Cheptoo Langat, Terry Allan Vik and Gertjan J. L. Kaspers
Curr. Oncol. 2025, 32(3), 162; https://doi.org/10.3390/curroncol32030162 - 12 Mar 2025
Viewed by 470
Abstract
The WHO Global Initiative for Childhood Cancer will likely increase the number of childhood cancer survivors in resource-poor countries. This study explored survivorship care in Kenya through parental reports on late effects and the follow-up needs of childhood cancer survivors. Parents of Kenyan [...] Read more.
The WHO Global Initiative for Childhood Cancer will likely increase the number of childhood cancer survivors in resource-poor countries. This study explored survivorship care in Kenya through parental reports on late effects and the follow-up needs of childhood cancer survivors. Parents of Kenyan childhood cancer survivors (under 18 years old) who completed treatment for at least one year were interviewed using semi-structured questionnaires from 2021 to 2022. Parents of 54 survivors were interviewed. Survivors had solid tumors (52%) and hematological tumors (48%). Most (52%) received chemotherapy combined with either surgery or radiotherapy. Many survivors (72%) experienced symptoms according to their parents. The most prevalent symptoms were pain (37%), fatigue (26%), and ocular problems (26%). Eleven percent of parents observed limitations in the daily activities of the survivors. Parents of survivors with two or more symptoms were more likely to rate symptoms as moderate to severe (p = 0.016). Parents expressed concern about late effects (48%). Only 28% were informed about late effects at the hospital, despite 87% indicating they would have welcomed this information. Follow-up care was deemed important by 98%. Recommendations included providing education about late effects and organizing survivor meetings. Survivorship clinics should be established to ensure that follow-up information and care are accessible. Full article
(This article belongs to the Special Issue Interventions to Prevent and Reduce Late Effects in Childhood, Adolescent, and Young Adult Cancer Survivors)
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17 pages, 235 KiB  
Article
Adaptation, Feasibility, and Acceptability of a Health Insurance Literacy Intervention for Caregivers of Pediatric Cancer Patients (CHAT-C)
by Amy Chevrier, Perla L. Vaca Lopez, Katie Rogers, Monique Stefanou, Karely M. van Thiel Berghuijs, Douglas Fair, Elyse R. Park, Anne C. Kirchhoff and Echo L. Warner
Curr. Oncol. 2025, 32(2), 69; https://doi.org/10.3390/curroncol32020069 - 28 Jan 2025
Cited by 1 | Viewed by 797
Abstract
We adapted CHAT, a four-session virtual program to help individuals affected by cancer manage insurance and medical costs for caregivers of pediatric cancer patients (called CHAT-C); we then pilot-tested CHAT-C. Eligible caregivers were ages 18+ and the primary caregiver to a pediatric cancer [...] Read more.
We adapted CHAT, a four-session virtual program to help individuals affected by cancer manage insurance and medical costs for caregivers of pediatric cancer patients (called CHAT-C); we then pilot-tested CHAT-C. Eligible caregivers were ages 18+ and the primary caregiver to a pediatric cancer patient (≤25 years old) diagnosed in the past five years and treated at Primary Children’s Hospital. We conducted engagement studios to adapt the program. Feedback was evaluated using a rapid qualitative analysis framework and included content preferences, navigator preferences, logistics/structure, timing of delivery, and feasibility/acceptability. A small pilot test of CHAT-C was conducted; feasibility, acceptability, and preliminary efficacy were evaluated based on enrollment rates, qualitative feedback, and baseline/follow-up surveys. Participants in the pilot (n = 14) were primarily white (93%), married (93%), female (86%), ages 40–49 (50%), and college-educated (57%). Most participants (64%) completed all four sessions of CHAT-C. Those who did not complete the sessions cited a lack of time, a child’s disease progression, and a perceived lack of benefit. Health insurance literacy (measured by nine items) improved by 10.8 points on average (SD = 6.0, range: 9–36) after CHAT-C. Caregivers of childhood cancer patients are willing to participate in a health insurance program, but some caregivers need less time-intensive options. Full article
(This article belongs to the Special Issue Interventions to Prevent and Reduce Late Effects in Childhood, Adolescent, and Young Adult Cancer Survivors)
12 pages, 467 KiB  
Article
Oncology Camp Participation and Psychosocial Health in Children Who Have Lived with Cancer—A Pilot Study
by Sarah O’Connell, Nathan O’Keeffe, Greg D. Wells and Sarah L. West
Curr. Oncol. 2024, 31(11), 7165-7176; https://doi.org/10.3390/curroncol31110528 - 15 Nov 2024
Viewed by 1080
Abstract
Children with lived cancer experience encounter adversity, therefore experiences promoting psychosocial health are necessary. This pilot study determined the impact of recreational oncology camps (ROC) on resilience, hope, social support, and mental well-being in youth who have lived with cancer. Youth (6–18 years) [...] Read more.
Children with lived cancer experience encounter adversity, therefore experiences promoting psychosocial health are necessary. This pilot study determined the impact of recreational oncology camps (ROC) on resilience, hope, social support, and mental well-being in youth who have lived with cancer. Youth (6–18 years) with cancer experience enrolled in an 11-day session of ROC (Muskoka, Ontario, Canada) were invited to participate. Participants completed a survey [Children’s Hope Scale (CHS), Child and Youth Resilience Measure (CYRM-R), Social Provisions Scale (SPS-5), and Short Warwick–Edinburgh Mental Wellbeing Scale (SWEMWBS)] on the first (T1) and last day (T2) of camp, and 3 months post-camp (T3). Repeated-measures ANOVAs evaluated differences in survey scores among time points. Ten participants (14.1 ± 2.5 years) were included in the analysis. CHS scores at T3 were lower than T1 and T2 (F = 9.388, p = 0.008). CYRM-R, SPS-5, and SWEMWBS scores were high but did not differ between time points. Hope decreased 3 months post-camp, suggesting a need for continued psychosocial support. Overall, the ROC environment is associated with positive psychosocial health. Full article
(This article belongs to the Special Issue Interventions to Prevent and Reduce Late Effects in Childhood, Adolescent, and Young Adult Cancer Survivors)
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