Feature Advancements in Section "Childhood, Adolescent and Young Adult Oncology"

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Childhood, Adolescent and Young Adult Oncology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 2606

Special Issue Editors


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Guest Editor
Division of Hematology/Oncology, Children’s Hospital of Eastern Switzerland, 9006 St. Gallen, Switzerland
Interests: survivorship; long-term follow-up care; neurooncology; AYA oncology
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Guest Editor
1. Division of Hematology/Oncology, Children’s Hospital of Eastern Switzerland, St. Gallen, Switzerland
2. Department of Oncology, University Children’s Hospital Zurich, 8032 Zurich, Switzerland
Interests: survivorship; long-term follow-up care; AYA oncology; oncopolicy

Special Issue Information

Dear Colleagues,

Given the increasing number of childhood, adolescent and young adult oncology survivors, treatment focus is shifting more and more to the quality of survival. The quality of survival is influenced by many factors during cancer diagnosis, treatment and follow up, encompassing many aspects, e.g., mental health, fertility, body image, etc. In order to cover all of these aspects, integrative care models are needed, including the transition process from pediatric to adult survivorship care.

We are pleased to invite you to profile care and transition models in different healthcare settings from different countries across the globe for this Special Issue. All potential elements of care and transition models can be covered, including initiatives from survivors, advocacy or NGO to enhance survivorship care. Rehabilitation services for this population should also be included.

This Special Issue aims to feature the multiprofessional and interdisciplinary care of cancer survivors, looking to new care models in the hospital or community setting or initiatives by advocacy organizations trying to enhance the quality of survival, including transition care models from pediatric- to adult-based care.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: survivorship care and transition from pediatric- to adult-based care.

We look forward to receiving your contributions.

Prof. Dr. Katrin Scheinemann
Dr. Maria Otth
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • childhood, adolescent and young adult cancer
  • survivorship
  • care models
  • transition
  • rehabilitation

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Published Papers (2 papers)

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16 pages, 1181 KiB  
Article
Internal Consistency and Floor/Ceiling Effects of the Gross Motor Function Measure for Use with Children Affected by Cancer: A Cross-Sectional Study
by Francesca Rossi, Monica Valle, Giovanni Galeoto, Marco Tofani, Paola Berchialla, Veronica Sciannameo, Daniele Bertin, Annalisa Calcagno, Roberto Casalaz, Margherita Cerboneschi, Marta Cervo, Annalisa Cornelli, Chiara Di Pede, Maria Esposito, Miriana Ferrarese, Paola Imazio, Maria Lorenzon, Lucia Longo, Andrea Martinuzzi, Gabriella Naretto, Nicoletta Orsini, Daniele Panzeri, Chiara Pellegrini, Michela Peranzoni, Fabiola Picone, Marco Rabusin, Federica Ricci, Claudia Zigrino, Giulia Zucchetti and Franca Fagioliadd Show full author list remove Hide full author list
Curr. Oncol. 2024, 31(9), 5291-5306; https://doi.org/10.3390/curroncol31090390 - 6 Sep 2024
Cited by 1 | Viewed by 1845
Abstract
Children/adolescents with cancer can develop adverse effects impacting gross motor function. There is a lack of gross motor function assessment tools that have been validated for this population. The aim of this multicenter cross-sectional study was to preliminary validate the 88-item Gross Motor [...] Read more.
Children/adolescents with cancer can develop adverse effects impacting gross motor function. There is a lack of gross motor function assessment tools that have been validated for this population. The aim of this multicenter cross-sectional study was to preliminary validate the 88-item Gross Motor Function Measure (GMFM-88) for use in children/adolescents with cancer, exploring internal consistency and floor/ceiling effect. Inclusion criteria regarded children/adolescents diagnosed with cancer on treatment or <1 year off therapy. The internal consistency was assessed using Cronbach’s α, and the floor–ceiling effects were calculated through percentage. This study involved 217 participants with heterogeneous neoplasm conditions. Internal consistency was good, with a Cronbach’s α of 0.989. Floor–ceiling effect analysis reveals that several items obtained a dichotomous scoring distribution in each of the five sub-scales of the GMFM-88. This can be explained by the heterogeneous clinical characteristics of the target population. The preliminary validation of GMFM-88 in a group of children/adolescents affected by cancer suggests that some items are not able to discriminate between different gross motor function levels, and therefore it does not represent an informative tool to measure gross motor function in children with cancer. Future research is needed to define which ones could be more useful for clinical practice. Full article
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31 pages, 691 KiB  
Systematic Review
Supervised Physical Activity Interventions in Children and Adolescents with Cancer Undergoing Treatment—A Systematic Review
by Nadja Battanta, Krystyna Lange, Sabine V. Kesting, Daniela Marx-Berger, Philip Heesen, Hannah Ober, Aron Onerup, Saskia M. F. Pluijm, Eva Scheler, Emma J. Verwaaijen, Katrin Scheinemann and Maria Otth
Curr. Oncol. 2025, 32(4), 234; https://doi.org/10.3390/curroncol32040234 - 17 Apr 2025
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Abstract
Background: A cancer diagnosis and its treatment often disrupt a child’s and adolescent’s normal level of physical activity, which plays a vital role in their development and health. They are therefore often less physically active during treatment than before the diagnosis or compared [...] Read more.
Background: A cancer diagnosis and its treatment often disrupt a child’s and adolescent’s normal level of physical activity, which plays a vital role in their development and health. They are therefore often less physically active during treatment than before the diagnosis or compared to healthy peers. Today, there is no comprehensive overview of the safety, feasibility, clinical effectiveness, and potentially long-lasting impact of physical activity (PA) interventions in this population. Methods: We conducted a systematic review in PubMed according to PRISMA guidelines to evaluate studies on PA interventions during cancer treatment in children and adolescents up to 25 years of age. We used the Joanna Briggs Institute’s critical appraisal tools to assess the risk of bias. Due to the heterogeneity in interventions and outcomes, we used descriptive approaches only to present the results. Results: Half of the 21 included studies were randomized controlled trials (10/21). PA interventions were found to be safe and feasible when tailored to the patient’s age, treatment phase, and clinical condition. Most studies reported improvements in physical fitness, strength, and quality of life, with some reductions in fatigue. Variability in interventions and outcomes, along with small sample sizes and heterogeneous patient populations, made it difficult to draw clear conclusions. Conclusions: PA appears to be a feasible and, in terms of injuries, safe adjunct to cancer treatment in children and adolescents. Despite promising trends, further large-scale, multicenter trials with standardized protocols are needed to better establish the long-term benefits and optimal interventions. Full article
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