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Cosmetics
Special Issues
Advanced Delivery Systems for Dermatologic and Dermocosmetics Products
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Advanced Delivery Systems for Dermatologic and Dermocosmetics Products

A special issue of Cosmetics (ISSN 2079-9284).

Deadline for manuscript submissions: 31 October 2024 | Viewed by 5837

Special Issue Editors

Dr. Bruno Fonseca-Santos

E-Mail Website
Guest Editor
Department of Biotechnology, Health Sciences Institute, Federal University of Bahia (UFBA), Salvador 40110-902, BA, Brazil
Interests: colloids; lyotropic liquid crystals; nanoparticulate systems; skin inflammation; drug delivery systems
Special Issues, Collections and Topics in MDPI journals
Dr. Marlus Chorilli

E-Mail Website
Guest Editor
Department of Drugs and Medicines, São Paulo State University—UNESP, Rodovia Araraquara Jaú, Km 1, Araraquara 14800-903, SP, Brazil
Interests: lipid-based carriers; drug delivery systems; in vivo assays; clinical assays
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The objective of developing delivery systems for skin is to enhance the effectiveness and efficiency of delivering active ingredients to specific target areas of the skin; this includes creating innovative delivery methods that optimize the absorption and penetration of dermatologic and dermocosmetic products, resulting in improved treatment outcomes and benefits. By developing advanced delivery systems, including nanomaterials and biomaterials, researchers and developers aim to overcome the limitations of conventional delivery methods, such as topical creams, gels and lotions, by increasing the bioavailability, penetration and sustained release of active ingredients; this may involve creating products with easy application methods, such as sprays, patches, and microneedles, that ensure accurate and consistent dosage administration. Moreover, these delivery systems strive to improve the sensory experience by minimizing potential side effects or skin irritations associated with certain active ingredients; this allows for better targeting of skin conditions, such as acne, eczema, hyperpigmentation, and ageing signs, as well as sun protection, moisturizer, skin-lightening products, and personal care products.

Dr. Bruno Fonseca-Santos
Dr. Marlus Chorilli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cosmetics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dermatology
  • photoaging
  • nanoparticles
  • penetration enhancers
  • skin penetration assessment
  • non-invasive efficacy methods
  • alternative methods for toxicity
  • sunscreens
  • vitamins
  • acne

Published Papers (3 papers)

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Research

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16 pages, 2621 KiB  
Article
Nanoemulsions Containing Passiflora quadrangularis L. Fruit Extracts for Cosmetic Application and Skin Efficacy Study
by Nareekan Yanasan, Worrapon Wangkananon, Surapol Natakankitkul and Kanokwan Kiattisin
Cosmetics 2024, 11(2), 57; https://doi.org/10.3390/cosmetics11020057 - 04 Apr 2024
Viewed by 806
Abstract
This study aimed to determine the anti-collagenase, anti-elastase, and anti-hyaluronidase activities of Passiflora quadrangularis fruit extracts (epicarp, mesocarp, endocarp, and seed), develop stable nanoemulsions, and evaluate the efficacy of the nanoemulsions containing extracts in human volunteers. The results indicated that the epicarp and [...] Read more.
This study aimed to determine the anti-collagenase, anti-elastase, and anti-hyaluronidase activities of Passiflora quadrangularis fruit extracts (epicarp, mesocarp, endocarp, and seed), develop stable nanoemulsions, and evaluate the efficacy of the nanoemulsions containing extracts in human volunteers. The results indicated that the epicarp and seed extracts exhibited collagenase, elastase, and hyaluronidase inhibition effects. Gallic acid was identified in the extracts, with the highest concentration found in the endocarp extract (1449.35 mg gallic acid/g extract) followed by the seed extract (839.63 mg gallic acid/g extract). The endocarp and seed extracts demonstrated good stability at different temperatures. Consequently, these extracts were selected for incorporation into nanoemulsions due to their high yield, excellent anti-tyrosinase and anti-aging activity, and good stability, making them suitable for cosmetic products. The nanoemulsions were prepared using the ultrasonication method, resulting in a particle size of 133.1 ± 0.8 nm, a polydispersity index of 0.33 ± 0.03, and a zeta potential of −61.8 ± 0.6 mV, indicating good stability. The nano-serum containing extracts was non-irritating and safe for the skin. Skin evaluation among human volunteers after 60 days of application revealed improvements in skin hydration and reduction in wrinkles. In conclusion, nanoemulsions containing P. quadrangularis fruit extracts have the potential to be effective cosmetic products. Full article
(This article belongs to the Special Issue Advanced Delivery Systems for Dermatologic and Dermocosmetics Products)
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23 pages, 11892 KiB  
Article
Nanoemulsions Containing Mucuna pruriens (L.) DC. Seed Extract for Cosmetic Applications
by Suwaporn Chookiat, Tinnakorn Theansungnoen, Kanokwan Kiattisin and Aekkhaluck Intharuksa
Cosmetics 2024, 11(1), 29; https://doi.org/10.3390/cosmetics11010029 - 12 Feb 2024
Viewed by 1965
Abstract
Mucuna pruriens is a medicinal plant whose seeds have various types of pharmacological activities and are used in many traditional medicines. The aim of this study was to evaluate the phytochemicals as well as the anti-aging, antioxidant, and moisturizing properties of seed extracts [...] Read more.
Mucuna pruriens is a medicinal plant whose seeds have various types of pharmacological activities and are used in many traditional medicines. The aim of this study was to evaluate the phytochemicals as well as the anti-aging, antioxidant, and moisturizing properties of seed extracts of M. pruriens var. pruriens and M. pruriens var. utilis. In addition, the best extract was selected for the development of nanoemulsions. M. pruriens var. utilis had the highest total phenolic and total flavonoid contents. It had good antioxidant activity (the IC50 of DPPH was 4.87 µg/mL, the FRAP value was 1.63 mg of FeSO4/mg of extract, and the percentage of lipid peroxidation was 80.19%) and anti-aging activity (the percentages of inhibition of hyaluronidase, collagenase, and elastase were 26.41%, 51.16%, and 22.78%, respectively). The occlusive factor was 46.12 ± 1.72. Therefore, M. pruriens var. utilis seed extract was selected for the preparation of nanoemulsions. The results showed that the size, PDI, and zeta potential of nanoemulsions containing M. pruriens var. utilis seed extract at day 30 did not significantly differ from those at day 0. In addition, the %EE was 63.46%. A study of skin permeation showed that the retention in the membrane after six hours of skin permeation study was 44.19%. Therefore, nanoemulsions containing M. pruriens var. utilis seed extract have good potential for further use in cosmetic applications. Full article
(This article belongs to the Special Issue Advanced Delivery Systems for Dermatologic and Dermocosmetics Products)
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Review

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21 pages, 403 KiB  
Review
Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids
by Inês Ferreira, Carla M. Lopes and Maria Helena Amaral
Cosmetics 2024, 11(1), 22; https://doi.org/10.3390/cosmetics11010022 - 06 Feb 2024
Cited by 1 | Viewed by 2711
Abstract
Acne vulgaris is a prevalent dermatological disorder that impacts the quality of life for millions of people around the world. The multifactorial nature of this disorder requires innovative and effective treatment strategies. Over time, there has been a growing interest regarding the use [...] Read more.
Acne vulgaris is a prevalent dermatological disorder that impacts the quality of life for millions of people around the world. The multifactorial nature of this disorder requires innovative and effective treatment strategies. Over time, there has been a growing interest regarding the use of natural topical therapies, with cannabinoids emerging as a promising group of compounds for investigation. In the context of acne treatment, cannabinoids are of particular interest due to their anti-acne properties, namely, lipostatic, anti-inflammatory, antiproliferative, and antimicrobial activities. Among these bioactive compounds, cannabidiol stands out as a notable derivative, exhibiting a promising spectrum of therapeutic actions. Pre-clinical and clinical studies have proven its ability to modulate sebum production, reduce inflammation, and inhibit bacterial proliferation—all of which are critical components in the pathogenesis of this dermatosis. This review provides a comprehensive overview of cannabinoids’ potential as a novel and holistic approach to acne vulgaris treatment and summarizes recent developments in this area. Full article
(This article belongs to the Special Issue Advanced Delivery Systems for Dermatologic and Dermocosmetics Products)
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