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Editorial Board Members' Collection Series: "Novel Delivery Systems for Dermocosmetic...
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Editorial Board Members' Collection Series: "Novel Delivery Systems for Dermocosmetic Applications"

A topical collection in Cosmetics (ISSN 2079-9284).

Viewed by 14243

Editors

Dr. Elisabetta Esposito

E-Mail Website
Collection Editor
Department of Chemical and Pharmaceutical Sciences, University of Ferrara, 44121 Ferrara, Italy
Interests: nanotechnology; lipid-based drug delivery systems; natural antioxidants; transdermal delivery systems; semisolid formulations
Special Issues, Collections and Topics in MDPI journals
Dr. Debora Santonocito

E-Mail Website
Collection Editor
Department of Drug and Health Sciences, University of Catania, V.le Andrea Doria, 6, 95125 Catania, Italy
Interests: drug delivery; nanomedicine; lipid nanoparticles; pharmaceutical technology
Special Issues, Collections and Topics in MDPI journals

Topical Collection Information

Dear Colleagues,

The skin is the body’s outermost organ, with pivotal functions in protection from external stimuli. Additionally, the skin is exposed to many risks, deriving from possible insults due to pollution or UV exposure, leading to premature ageing, as well as inflammation or infections. Therefore, to counteract these deleterious effects, several approaches have been developed, spanning from innovative delivery systems based on nanotechnological approaches, to functional ingredients, such as novel plant-derived phytochemicals.

In particular, nanoplatforms have emerged as promising carriers of treatments to improve the skin barrier’s function and to enhance their topical delivery. Indeed, nanoplatforms possess many advantages, including high biocompatibility, controlled release, increased moisturizing and emollient power, easy scale-up, and low-cost production. A variety of delivery systems have been investigated for topical application, such as lipid and polymeric nanoparticles, patches, emulsions, liposomes, and microneedles. This Special Issue’s aim is to collect the most recent research to provide an update of the state of the art, and to highlight new directions for investigations into the use of innovative formulations for dermatologic and dermocosmetic applications

Prof. Dr. Elisabetta Esposito
Dr. Debora Santonocito
Collection Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cosmetics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • innovative delivery systems
  • skin delivery
  • natural functional ingredients
  • dermocosmetic applications

Published Papers (4 papers)

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2024

18 pages, 1720 KiB  
Article
Effects of Lipid Phase Content on the Technological and Sensory Properties of O/W Emulsions Containing Bemotrizinol-Loaded Nanostructured Lipid Carriers
by Debora Santonocito, Carmelo Puglia and Lucia Montenegro
Cosmetics 2024, 11(4), 123; https://doi.org/10.3390/cosmetics11040123 - 19 Jul 2024
Viewed by 1945
Abstract
Different lipid phase ratios (12, 14, and 16% w/w) were assessed for their ability to affect the technological and sensory properties of O/W emulsions in which bemotrizinol (BMTZ), a broad-spectrum sunscreen agent, was incorporated free or loaded into nanostructured lipid [...] Read more.
Different lipid phase ratios (12, 14, and 16% w/w) were assessed for their ability to affect the technological and sensory properties of O/W emulsions in which bemotrizinol (BMTZ), a broad-spectrum sunscreen agent, was incorporated free or loaded into nanostructured lipid nanocarriers (NLC) to reduce its release from the vehicle and, hence, its skin permeation. The following technological properties were evaluated in vitro: spreadability, viscosity, pH, occlusion factor, BMTZ release, and sun protection factor (SPF). Sensory attributes were assessed by panelists in three different phases: before/during pick-up, rub-in, and after application. Raising the lipid phase ratio led to an increase in viscosity (from 8017 ± 143 cPs to 16,444 ± 770 cPs) and to a corresponding decrease in spreadability (from 9.35 ± 0.21 cm to 7.50 ± 0.10 cm), while the incorporation of BMTZ-loaded NLC determined a decrease in the occlusion factor (from 47.75 ± 1.16 to 25.91 ± 1.57) and an increase in SPF (from 6% for formulations containing 12% lipid phase to 15% for formulations containing 16% lipid phase). No BMTZ release was observed from all emulsions. Sensory attributes were mainly affected by the lipid phase ratio. These results suggest that the lipid phase ratio and BMTZ incorporation into NLC could contribute to determining the technological and sensory properties of O/W emulsions. Full article
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19 pages, 1474 KiB  
Review
Plant Essential Oil Nanoemulgel as a Cosmeceutical Ingredient: A Review
by Xing Fui Yap, Seow Hoon Saw, Vuanghao Lim and Chin Xuan Tan
Cosmetics 2024, 11(4), 116; https://doi.org/10.3390/cosmetics11040116 - 10 Jul 2024
Cited by 2 | Viewed by 2711
Abstract
Essential oils (EOs) are concentrated, hydrophobic volatile compounds derived from different parts of plants. They are recognized for their diverse and versatile functional properties. Approximately 90% of EOs are administered via topical or transdermal routes. However, EOs are susceptible to oxidation, and their [...] Read more.
Essential oils (EOs) are concentrated, hydrophobic volatile compounds derived from different parts of plants. They are recognized for their diverse and versatile functional properties. Approximately 90% of EOs are administered via topical or transdermal routes. However, EOs are susceptible to oxidation, and their high volatility often poses a challenge to the transdermal delivery of their bioactive constituents. Additionally, the direct application of pure EOs on the skin may result in irritating effects. Hence, various novel carrier systems have been explored for the topical application of EOs. Among these, nanoemulgel has received particular attention from the cosmeceutical industry. It is a hybrid technology combining nanoemulsion and a gelling phase, which can enhance the bioadhesivity of EOs, at the same time minimizing their irritating effects. This review summarizes the methods of EO extraction, steps and factors influencing the preparation of EO nanoemulgel, and characterization parameters for nanoemulgel studies. The potential cosmeceutical applications of EO nanoemulgels as an anti-inflammatory, antimicrobial, antioxidant, and penetration enhancer are also compiled and discussed. Full article
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21 pages, 1291 KiB  
Review
A Comprehensive Review of Essential Oil–Nanotechnology Synergy for Advanced Dermocosmetic Delivery
by Redouane Achagar, Zouhair Ait-Touchente, Rafika El Ati, Khalid Boujdi, Abderrahmane Thoume, Achraf Abdou and Rachid Touzani
Cosmetics 2024, 11(2), 48; https://doi.org/10.3390/cosmetics11020048 - 27 Mar 2024
Cited by 2 | Viewed by 4575
Abstract
This review investigates the convergence of nanotechnology and essential oils in advanced dermocosmetic delivery. It outlines the pivotal role of inorganic and polymeric nanoparticles, such as titanium dioxide, zinc oxide, and gold nanocarriers, in cosmeceutical applications, facilitating slow release, deeper skin penetration, and [...] Read more.
This review investigates the convergence of nanotechnology and essential oils in advanced dermocosmetic delivery. It outlines the pivotal role of inorganic and polymeric nanoparticles, such as titanium dioxide, zinc oxide, and gold nanocarriers, in cosmeceutical applications, facilitating slow release, deeper skin penetration, and increased retention of active compounds. Essential oils, renowned for therapeutic benefits, face translation challenges due to volatility and low water solubility. This review explores the potential use of plant nanovesicles as carriers, emphasizing safety, stability, and scalability, offering a sustainable and cost-effective industrial application. Nanomaterial integration in consumer products, particularly cosmetics, is prevalent, with nanocarriers enhancing the permeation of bioactive compounds into deeper skin layers. The review emphasizes recent nanotechnological advancements, covering nanoparticle penetration, experimental models, and therapeutic applications in dermatology, ranging from non-invasive vaccination to transdermal drug delivery. Additionally, the review delves into nanomaterials’ role in addressing skin aging, focusing on tissue regeneration. Nanomaterials loaded with cosmeceuticals, such as phytochemicals and vitamins, are explored as promising solutions to mitigate signs of aging, including wrinkles and dry skin, providing innovative approaches to skin rejuvenation. Overall, the review offers a comprehensive synthesis of essential oil–nanoparticle synergy, shedding light on the current landscape and future potential of advanced dermocosmetic delivery systems. Full article
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23 pages, 6859 KiB  
Article
Formulation and Characterization of Niacinamide and Collagen Emulsion and Its Investigation as a Potential Cosmeceutical Product
by Elena Dănilă, Durmuș Alpaslan Kaya, Valentina Anuța, Lăcrămioara Popa, Alina Elena Coman, Ciprian Chelaru, Rodica Roxana Constantinescu, Cristina Dinu-Pîrvu, Mădălina Georgiana Albu Kaya and Mihaela Violeta Ghica
Cosmetics 2024, 11(2), 40; https://doi.org/10.3390/cosmetics11020040 - 8 Mar 2024
Cited by 1 | Viewed by 4073
Abstract
Cosmeceuticals are one of the fast-growing areas of the natural personal care industry. Cosmeceuticals are cosmetic products with medicinal or drug-like benefits that can affect the biological functioning of the skin depending on the ingredients in the composition. The development of one formulation [...] Read more.
Cosmeceuticals are one of the fast-growing areas of the natural personal care industry. Cosmeceuticals are cosmetic products with medicinal or drug-like benefits that can affect the biological functioning of the skin depending on the ingredients in the composition. The development of one formulation acting on the dermis and stimulating the collagen production is very important for the hydration of the skin. The association of collagen with other ingredients can have a positive effect on increasing the natural production of collagen in the skin. An example of such an ingredient is niacinamide, which, having a recognized nutritional value, has been quite recently studied. Considering these aspects, this study focused on developing oil-in-water (O/W) emulsions, based on natural ingredients (vegetable oils, floral waters, and essential oils) and hydrolyzed collagen and niacinamide as active ingredients, and on evaluating the stability, pH, optical, superficial, rheological and textural properties, as well as microbiological tests of the emulsions, in order to investigate their potential as a cosmeceutical product. All the obtained emulsions proved to be stable at variable temperatures and had a pH value compatible with natural pH of the skin, allowing their safe application. Over goniometric analysis, a partial wetting and a hydrophilic character of the emulsions were emphasized. Following the rheological analyses, all dermatocosmetic emulsions exhibited non-Newtonian pseudoplastic behavior and a thixotropic character, these properties being very important for their production process and their application on the skin surface to generate an optimal therapeutic effect. The textural characteristics recorded for all emulsions indicated adequate spreadability at the application site. All tested samples respected the Pharmacopoeia limits of microbiological contamination. All prepared emulsions have good stability, are safe for the skin and have appropriate physicochemical and microbiological characteristics; therefore, they can be used as a cosmeceutical product. Full article
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