Biofilm-Targeting Surfaces and Coatings in Oral Environment

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: closed (30 December 2022) | Viewed by 2300

Special Issue Editors

Department of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Interests: oral microbiology; biofilms; extracellular matrix; biofilm dynamics; super-resolution imaging; bioactive surfaces & materials; in vivo models
Department of Chemical and Biomolecular Engineering, School of Engineering & Applied Sciences Department of Orthodontics | Department of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Interests: micro-robotics; biofilm treatment; microfluidics; antimicrobial drug delivery; microbubble; microemulsion; hierarchical structures; interfacial self-assembly

Special Issue Information

Dear Colleagues,

We would like to announce and welcome submissions to a Special Issue of Coatings entitled Biofilm-Targeting Surfaces and Coatings in Oral Environments.

Biofilm formation is a key virulence factor for a wide range of microorganisms causing chronic infections in humans. In the oral cavity, biofilms formed on the tooth, mucosal, or abiotic (e.g., implants and restorative materials) surfaces can cause painful and costly infectious diseases such as dental caries (tooth decay), periodontal diseases, and peri-implantitis. The multifactorial nature of biofilm development and drug resistance imposes great challenges for the use of conventional antimicrobials and indicates the need for innovative antibiofilm modalities. Recent advances in material science and surface engineering have led to the development of novel bioactive surfaces and coatings, providing new directions for establishing effective biofilm-targeting approaches.

In this Special Issue, we call for submissions of manuscripts (research articles, reviews, and communications) focusing on the development of novel antibiofilm surfaces and coatings to address unmet needs in oral health. Topics of interest include, but are not limited to, the following:

  • Antibiofilm dental materials
  • Antibiofilm surface modifications
  • Antibiofilm surface topography
  • Antimicrobial coatings
  • Adhesion-targeting/adhesion-blocking approaches
  • Stimuli-responsive (“smart”) antibiofilm surfaces
  • Bio-inspired anti-biofouling materials
  • Self-cleaning surface coatings
  • Biofilm–surface interactions
  • Material–microbe-host interactions
  • Biofilm-targeting mechanisms
  • Impact of antibiofilm materials on oral microbiota
  • In vitro/in vivo models for evaluating antibiofilm dental materials

Dr. Zhi Ren
Dr. Minjun Oh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral biofilms
  • biofilm targeting
  • antibiofilm surfaces
  • antibiofilm coatings
  • material science

Published Papers (1 paper)

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Research

15 pages, 35313 KiB  
Article
Metal Release and Surface Degradation of Fixed Orthodontic Appliances during the Dental Levelling and Aligning Phase: A 12-Week Study
by António Fróis, Alexandra Ricardo Mendes, Sónia Alves Pereira and Cristina Santos Louro
Coatings 2022, 12(5), 554; https://doi.org/10.3390/coatings12050554 - 20 Apr 2022
Cited by 3 | Viewed by 1909
Abstract
The purpose of the present study is twofold: (i) to assess the salivary nickel, chromium, and iron concentrations and (ii) to characterize the surface microstructure of the typical commercially available Ni-containing metallic appliances during the first 12-week orthodontic treatment period. A total of [...] Read more.
The purpose of the present study is twofold: (i) to assess the salivary nickel, chromium, and iron concentrations and (ii) to characterize the surface microstructure of the typical commercially available Ni-containing metallic appliances during the first 12-week orthodontic treatment period. A total of 85 unstimulated saliva samples were collected from patients before treatment, after 2 days, and after 1, 4, and 12 weeks. Salivary ion concentrations were determined by inductively coupled plasma optical emission spectroscopy, and data were analyzed with the Statistical Package for Social Sciences (IBM SPSS) software. The recorded mean metal concentrations were in the ranges of 132–175 µg/L for Ni, 171–192 µg/L for Cr, and 826–1023 µg/L for Fe. No statistically significant variations were observed between the different study times, and the null hypothesis (the concentrations of metallic ions in patients’ saliva did not significantly change after the placement of the orthodontic appliances) was accepted (p > 0.05). Mean salivary metallic ions were below toxic levels, and no adverse clinical reactions were registered. The intraoral surface degradation of the fixed components was corroborated by optical microscopy, scanning electron microscopy, and energy dispersive spectrometry. Microstructural analysis after complete orthodontic procedure confirmed different corrosion types, from pitting to biocorrosion. Full article
(This article belongs to the Special Issue Biofilm-Targeting Surfaces and Coatings in Oral Environment)
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