SERS: Analytical and Biological Challenges

Dear Colleagues,

Raman spectroscopy is attracting wide interest in several fields due to fingerprint molecular identification, the availability of portable or optical fiber equipped instruments and, most of all, the low Raman cross-section of water that makes it suitable for aqueous or biological samples. Nevertheless, anelastic Raman scattering is an intrinsic unfavored phenomenon, and a constantly increasing community is applying nanotechnology in order to amplify the far field signals by means of so-called electromagnetic as well as chemical enhancement. Surface-enhanced Raman spectroscopy (SERS) is therefore emerging in sensing applications, with sensitivities currently established at the single-molecule level. The route to upgrading SERS to practical applications indeed disseminates new challenges, such as addressing complex biological matrixes, favoring target-selective interactions, aiming qualitative/quantitative estimations, and building robust models for multicomponent analysis. All of them, and many others, are engaged by means of experimental and computational investigations. This Special Issue will collect the best contributions of a wide community of scientists to rationalize and challenge the limits of SERS in sensing technology.

Dr. Lucio Litti
Guest Editor

If you want to learn more information or need any advice, you can contact the Special Issue Editor Tammy Zhang via directly.

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