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Chemosensors, Volume 13, Issue 12

December 2025 - 31 articles

Cover Story: Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are emerging contaminants of global concern, requiring sensitive and highly selective detection methods. Stringent regulations imposed by the Environmental Protection Agency drive the development of novel PFAS sensors. Molecularly imprinted polymers and immunoassays are promising approaches due to their specific interactions with target molecules, leading to measurable optical or electrochemical responses. Various nanomaterials, including metal oxide nanoparticles, carbon-based materials such as carbon dots, polymer coatings, and MXenes, have been explored; however, many approaches still fail to achieve adequate limits of detection, sensitivity, or selectivity. This contribution reviews recent advances in nanomaterial-based PFAS sensors, emphasizing strategies to improve sensitivity, selectivity, and reliability in complex matrices. View this paper
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Articles (31)

  • Article
  • Open Access
248 Views
16 Pages

Chrysanthemum, a traditional medicinal and edible plant, possesses diverse health-promoting properties attributed to its rich profile of bioactive compounds. However, the intrinsic quality, influenced by the composition of fundamental components like...

  • Article
  • Open Access
352 Views
16 Pages

Eco-Friendly Synthesis and Paper Immobilization of AgNPs for Portable Colorimetric Detection of Hg2+ in Water

  • Nevena Radivojević,
  • Sanja Knežević,
  • Stefan Graovac,
  • Vladimir Rajić,
  • Tamara Terzić,
  • Nebojša Potkonjak,
  • Tamara Lazarević-Pašti and
  • Vedran Milanković

Mercury’s severe toxicity and persistence demand fast, low-cost, and sustainable detection. In this work, a Juglans regia ethanolic extract is introduced as an efficient biogenic reducing and stabilizing agent for the green synthesis of silver...

  • Review
  • Open Access
440 Views
24 Pages

Harmful substances in food and agricultural environments pose significant risks to human health, necessitating the development of sensitive detection technologies. Electrochemical sensors are ideal for rapid monitoring because of their low cost, high...

  • Article
  • Open Access
398 Views
12 Pages

Detection of Mercury Ions Using Graphene Nanoribbon-DNA Sensors Fabricated via Template Methods

  • Jiaojiao Da,
  • Haixia Shi,
  • Vesna Antic,
  • Milica Balaban,
  • Bing Xie and
  • Li Gao

To enhance the sensitivity of graphene-DNA sensors for Hg2+ detection, a novel graphene nanoribbon-DNA sensor was fabricated using a template-assisted approach. Silicon nanowires served as templates to decorate the graphene device, followed by plasma...

  • Article
  • Open Access
420 Views
14 Pages

Scandium-modified carbon dots (Sc-oCDs) were synthesized in this work through a solid-phase approach. The prepared Sc-oCDs exhibited excitation-independent emission properties, as well as photostability against pH, ionic strength, and UV irradiation....

  • Review
  • Open Access
466 Views
27 Pages

Recent Progress in Nanomaterials for Electrochemical Sensing of Natural Bioactive Compounds

  • Branka B. Petković,
  • Miloš Ognjanović and
  • Dalibor M. Stanković

The market for bioactive compounds of natural origin has expanded greatly over the past few years. These compounds can be found as individual supplements or food additives. Due to the importance of this market, incorrect data on their composition can...

  • Article
  • Open Access
532 Views
10 Pages

Polymer Electrolyte-Gated Organic Electrochemical Transistors for Bioinspired Neuromorphic Computing

  • Banghua Wu,
  • Lin Gao,
  • Yujie Peng,
  • Changjian Liu,
  • Canghao Xu,
  • Haihong Guo,
  • Yong Huang and
  • Junsheng Yu

Organic electrochemical transistors (OECTs) are compelling artificial synapses because mixed ionic–electronic coupling and transport enables low-voltage, analog weight updates that mirror biological plasticity. Here, we engineered solid-state,...

  • Review
  • Open Access
1,863 Views
52 Pages

The rapid emergence of novel psychoactive substances (NPSs) after 2020 has created one of the most dynamic analytical challenges in modern forensic science. Hundreds of new synthetic cannabinoids, synthetic cathinones, synthetic opioids, hallucinogen...

  • Article
  • Open Access
328 Views
18 Pages

Development and Application of Online Rapid Monitoring Devices for Volatile Organic Compounds in Soil–Water–Air Systems

  • Xiujuan Feng,
  • Haotong Guo,
  • Jing Yang,
  • Chengliang Dong,
  • Fuzhong Zhao and
  • Shaozhong Cheng

To overcome the limitations of lengthy laboratory testing cycles and insufficient on-site responsiveness, this study developed an online rapid monitoring device for volatile organic compounds (VOCs) in soil–water–air systems based on phot...

  • Article
  • Open Access
572 Views
21 Pages

A Machine Learning-Based Calibration Framework for Low-Cost PM2.5 Sensors Integrating Meteorological Predictors

  • Xuying Ma,
  • Yuanyuan Fan,
  • Yifan Wang,
  • Xiaoqi Wang,
  • Zelei Tan,
  • Danyang Li,
  • Jun Gao,
  • Leshu Zhang,
  • Yixin Xu and
  • Xueyao Liu
  • + 3 authors

Low-cost sensors (LCSs) have rapidly expanded in urban air quality monitoring but still suffer from limited data accuracy and vulnerability to environmental interference compared with regulatory monitoring stations. To improve their reliability, we p...

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Chemosensors - ISSN 2227-9040