Chemiluminescent and Bioluminescent Sensors

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Optical Chemical Sensors".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1513

Special Issue Editor


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Guest Editor
Department of Optical Nanoscopy, Institut für Nanophotonik Göttingen e.V., Hans-Adolf-Krebs-Weg 1, 37077 Göttingen, Germany
Interests: bioluminescence; biosensors; bioluminescence imaging; fluorescent proteins; super-resolution microscopy

Special Issue Information

Dear Colleagues,

Light emissions driven by chemiluminescence and bioluminescence as a result of a (bio)chemical reaction provide the functional basis for a diverse range of luminescent sensors. These sensors enable non-invasive optical imaging and high-sensitivity and high-specificity detection, and have found widespread use in many different areas including biomedicine, environmental science, food monitoring, and forensics. This Special Issue will highlight some of the latest research in the field of chemiluminescent and bioluminescent sensors, with a focus on the development of new luminescent sensors with improved properties and applications.

Both original research papers and review articles, including (but not limited to) the following areas, are welcome:

- The design and construction of chemiluminescent/bioluminescent sensors;

- Chemiluminescent/bioluminescent assays;

- BRET sensors;

- Bioluminescence imaging;

- The development of luminescence imaging instrumentation;

- Applications of chemiluminescent/bioluminescent probes in biology, medicine, molecular diagnostics, analytical chemistry, and industry.

Dr. Carola Gregor
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chemiluminescence
  • bioluminescence
  • biosensor
  • luciferase
  • luciferin
  • imaging

Published Papers (1 paper)

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Research

16 pages, 1570 KiB  
Article
Easy-to-Use Chemiluminescent-Based Assay for a Rapid and Low-Cost Evaluation of the Antioxidant Activity of Cosmetic Products
by Seyedeh Rojin Shariati Pour, Donato Calabria, Augusto Nascetti, Domenico Caputo, Giampiero De Cesare, Massimo Guardigli, Martina Zangheri and Mara Mirasoli
Chemosensors 2024, 12(2), 25; https://doi.org/10.3390/chemosensors12020025 - 09 Feb 2024
Viewed by 1263
Abstract
New cosmetic formulations are continuously requested by the market and the ingredients are constantly evolving. Recently the use of antioxidants has gained success and, in this context, analytical methods able to quickly and easily assess the antioxidant activity of cosmetics would make it [...] Read more.
New cosmetic formulations are continuously requested by the market and the ingredients are constantly evolving. Recently the use of antioxidants has gained success and, in this context, analytical methods able to quickly and easily assess the antioxidant activity of cosmetics would make it possible to carry out analyses on new formulations even within the manufacturing process without the need for specialized laboratories and personnel, thus evaluating directly on-site the effectiveness and the shelf life of products. In this work, a chemiluminescent inhibition assay was developed for determining the total antioxidant activity in cosmetic products. The method was based on the luminol/enhancers/hydrogen peroxide/horseradish peroxidase chemiluminescent system, which generates light signals measurable through simple and compact instrumentation. The formation of the chemiluminescent signal is inhibited by the presence of antioxidant substances while it is restored once all the antioxidant molecules have been oxidized. The time of appearance of the light signal is related to the total antioxidant activity. The assay was carried out exploiting an integrated device comprising a microwell plate coupled with an array of amorphous silicon hydrogenated photosensors enclosed in a mini-dark box. The method was optimized in terms of concentrations and volumes of the required reagents and sample pre-treatment. A calibration curve was generated taking as a reference the antioxidant activity of ascorbic acid obtaining a detection limit of 10 µM. The developed method was applied to cosmetic products currently on the market as well as on spiked samples in order to evaluate the performance of the methods in terms of sensitivity, accuracy, and reproducibility. Full article
(This article belongs to the Special Issue Chemiluminescent and Bioluminescent Sensors)
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