Special Issue "Biology of Boron Neutron Capture Therapy (BNCT)"

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 30 April 2020.

Special Issue Editors

Prof. Wolfgang Sauerwein
E-Mail Website
Guest Editor
Professor (retired), Medical Faculty, Department for Radiation Oncology, University Duisburg Essen, 45122 Essen, Germany
Interests: radiation oncology; hadron therapy (protons, heavy and light ions, fast neutrons, boron neutron capture therapy—BNCT); radiotherapy of eye tumors; use of Monte Carlo calculations to optimize radiotherapy; international cooperation in medicine
Dr. Amanda Elena Schwint
E-Mail Website
Guest Editor
1. Head Radiation Pathology Division, Department of Radiobiology, National Atomic Energy Commission (CNEA), San Martín, Provincia de Buenos Aires B1650KNA, Argentina;
2. Principal Investigator of the National Research Council of Argentina (CONICET), Argentina
Interests: boron neutron capture therapy (BNCT) radiobiology; particle therapy; translational in vivo BNCT studies; clinical veterinary BNCT studies; interdisciplinary national and international collaborations
Prof. Mitsuko Masutani
E-Mail Website1 Website2
Guest Editor
1. Professor, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan
2. Specially Appointed Chief, Lab of Collaborative Research, Division of Cellular Signaling, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
Interests: radiation oncology; biology in anti-cancer treatment
Prof. John Hopewell
Guest Editor
1. Professor and Director of Radiobiological Research (retired), University of Oxfords, OX1 2JD Oxford, UK;
2. Consultant Radiobiologist (retired), United Oxford Hospitals NHS Trust, Department of Radiotherapy, Churchill Hospital, OX3 7LE Oxford, UK
Interests: application of the principles of radiation biology to improve the application of different approaches to clinically radiation therapy

Special Issue Information

Dear Colleagues,

The appearance of hospital-based epithermal neutron sources has made boron neutron capture therapy (BNCT) a dedicated focus of innovative developments in radiation oncology. All future clinical applications have to be based on carefully performed pre-clinical investigations. At this very moment, it seems appropriate and important to collect results of recent preclinical and early clinical research and publish them together with intelligible and clear reviews of the most challenging aspects of BNCT.

In this Special Issue of Cells, we invite your contributions, in the form of original research articles, reviews, or shorter perspective articles, on all aspects related to the theme of BNCT.

Relevant topics include, but are not limited to, the following:

  • Radiation biology for BNCT;
  • Cell-based studies;
  • Preclinical animal studies;
  • Drug development for BNCT;
  • Impact of BNCT on the proteomic profile and omics approaches;
  • Boron imaging;
  • Mechanisms of action of BNCT;
  • Abscopal effect of BNCT;
  • Early clinical trials;
  • Biomarkers for therapeutic optimization.

Dr. Wolfgang Sauerwein
Dr. Amanda Schwint
Prof. Mitsuko Masutani
Prof. John Hopewell
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • boron neutron capture therapy (BNCT)
  • radiation biology
  • radiation oncology
  • clinical trials
  • drug development
  • imaging

Published Papers

This special issue is now open for submission.
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