Biology of Boron Neutron Capture Therapy (BNCT) 2021

Dear Colleagues,

The appearance of hospital-based epithermal neutron sources has made boron neutron capture therapy (BNCT) a dedicated focus of innovative developments in radiation oncology. All future clinical applications have to be based on carefully performed pre-clinical investigations. At this very moment, it seems appropriate and important to collect results of recent preclinical and early clinical research and publish them together with intelligible and clear reviews of the most challenging aspects of BNCT.

This Special Issue of Cells is for contributions on all cytobiological aspects related to BNCT. You are invited to submit your contributions in the form of original research articles, reviews, or shorter perspective articles.

Relevant observations made at the cellular level could come from the following areas:

Radiation biology for BNCT;
Cell-based studies;
Preclinical animal studies;
Drug development for BNCT;
Impact of BNCT on the proteomic profile and omics approaches;
Boron imaging;
Mechanisms of action of BNCT;
Abscopal effect of BNCT;
Early clinical trials;
Biomarkers for therapeutic optimization.

Prof. Wolfgang Sauerwein
Prof. Mitsuko Masutani
Prof. John Hopewell
Guest Editors

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