New Advances in Cardiac and Vascular Physiology
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 51
Special Issue Editor
Special Issue Information
Dear Colleagues,
Our understanding of cardiac and vascular physiology and pathophysiology continues to evolve. The number of deaths from coronary artery disease has decreased remarkably in the last 50 years, but the incidence of chronic heart failure is increasing, despite current best practices. The role of the immune system in the evolution of vascular injury such as aneurysms and in cardiac remodeling after stress or injury is not yet completely understood. The alpha-adrenergic receptor has a stronger role in cardiac responses than we previously believed. Cross-specialism understanding between cancer therapeutics and cardiac toxicity is increasingly valued, to the extent that the new subspecialty of cardio-oncology has emerged. Information on the roles of new receptor families such as proton-sensing GPCRs is emerging. A pandemic has passed but left us with endemic exposures and unanswered questions about lasting cardiac and vascular effects. It is necessary to increase awareness around the long-term impact of environmental exposures as aggravating risks, as well as the current status of once-promising interventions such as ischemic preconditioning and the clinical efficacy and utility of remote preconditioning. The role of both maternal and paternal epigenetic influences and the translatable utility of zebrafish and Drosophila models in elucidating those effects are only now being fully appreciated. This Special Issue will provide comprehensive updates on a wide range of potential pathophysiological processes related to cardiac and vascular disease processes. We hope that you will consider joining us.
Prof. Dr. Robert M. Lust
Guest Editor
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Keywords
- environmental exposure
- immune responses
- remodeling
- receptors
- ischemia
- pre-conditioning
- post-conditioning
- heart failure
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