Mechanisms of Respiratory Diseases

Dear Colleagues,

Understanding the mechanisms of respiratory diseases related to environmental exposure is a major challenge. The focus of this Special Issue is on the research of stressors such as particles, smoke, ozone or other inhaled agents activating inflammatory pathways and non-resolving, progressive lung destruction and fibrosis and exacerbation by viral infections. Contributions are invited that help to understand the role of innate receptors such as TLR, NLRP, cGAS/STING, ferroptosis, autophagy, senescence or cytokines such as IL-1, TNF and FASL to elicit host innate immune responses leading to inflammatory diseases.

The interplay between altered microbiota composition and metabolites linked to inflammation is a factor to be considered in pathogenesis. Translational contributions including defined inhibitors in rodents and human cell culture are of interest, and recent discoveries for this thematic issue of Cells are welcome.

Prof. Dr. Bernhard Ryffel
Dr. David Rios-Covián
Guest Editors

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