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Special Issue "Cellular and Molecular Biology of NF-κB"
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (31 January 2016).
Institute of Infection, Immunology and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow, G12 8TA, UK
Interests: NF-kappaB; ubiquitination; phosphorylation; transcriptomics; inflammation
The nuclear factor κB (NF-κB) family of transcription factors plays an essential role in regulating inducible transcriptional responses in key physiological processes, including cell proliferation and survival, cellular differentiation, and the immune response. The importance of NF-κB in these processes is reflected in the target genes under its direct control, which include cytokines, chemokines, regulators of antigen presentation and cell adhesion, and regulators of cell death and proliferation. Its role in regulating inducible transcription in the immune system has earned NF-κB the title of master regulator of the immune response, but an important role for NF-κB has also been identified in the development and progression of cancer where it often found to be constitutively active. Historically, most studies of NF-κB have focused on the mechanisms that lead to activation, providing a wealth of mechanistic detail, however, more recently, studies have brought attention to the mechanisms directly regulating NF-κB transcriptional activity in the nucleus. This Special Issue offers an open access forum to gather original review articles addressing all aspects of NF-κB cellular and molecular biology. We welcome contributions that cover the fundamental mechanisms controlling NF-κB activation and transcriptional activity, as well as the role of NF-κB in health and disease.
Dr. Ruaidhri Carmody
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- signal transduction
- post-translational modification