Pathophysiology and Molecular Targets in Myeloid Neoplasia

Dear Colleagues,

Myeloid cancers developing from the aging hematopoietic system share common genetic and epigenetic aberrations, irrespective of the clinical phenotype. While current treatment options are clearly focused on the disease phenotype and the underlying driver mutations, cancers within the myeloid spectrum rather represent a continuum of diseases. The underlying genetic and epigenetic landscape, comparable metabolic requirements, common functional dependencies, and shared interface with the immune system may facilitate the definition of pan-myeloid disease mechanisms and therapeutic targets. Identification of common pathophysiologic mechanisms may facilitate development of therapies to prevent progression or induce regression of the underlying clonal landscape. In this Special Issue, we aim to focus on commonalities and differences between preleukemic conditions and various blood cancers of the myeloid spectrum that may serve as therapeutic targets in the future. Contributions may therefore include primary research articles, reviews, as well as perspectives (if solicited by the editorial board).

Dr. Florian H. Heidel
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.