Cell Behavior Under Blood Flow
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 January 2026 | Viewed by 386
Special Issue Editors
Interests: hematology; blood banking; transfusion medicine; red cell storage lesion
Interests: viscoelasticity of multicellular systems; biophysics; biomechanics; effects along biointerfaces
Interests: red blood cells; RBC deformability; RBC fragility; RBC storage; biorheology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Blood components and endothelial cells encounter varying levels of shear (mechanical) stress during circulation. In vivo, shear stress can range from a few Pa to 20–50 Pa in an artery with a stenotic lesion. Exposure to elevated levels of mechanical stress can lead to subcellular structural changes due to cell strain, potentially resulting in alterations in membrane composition and biochemical and biophysical properties. All these cellular changes can ultimately initiate cell injury and dysfunction.
Accordingly, studying cellular responses to applied mechanical stress holds fundamental significance. In this Issue, we aim to compile reports of new research addressing the effects of mechanical stress on the functioning of cells in the bloodstream. We encourage the submission of papers that allow readers to explore this topic from biochemical and biophysical perspectives, focusing on the molecular mechanisms involved. We encourage scholars to employ a variety of methods to solve the research problem, ranging from theoretical and experimental to numerical.
Dr. Alexander Gural
Dr. Ivana Pajic-Lijakovic
Dr. Gregory Barshtein
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- blood flow
- shear stress
- red blood cells
- white blood cells
- platelets
- endothelial cells
- cell stimulation
- mechanical stress
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