Advances in Renal Epithelial Cells

Dear Colleagues,

The renal epithelial cells that compose the nephron play important roles in physiological processes, from body fluid regulation to ion and acid/base homeostasis, as well as in pathological processes, during kidney repair following injury or tumorigenesis. The advent of new technologies, such as spatial transcriptomics or 3D cultures, have provided researchers with powerful tools to study cell properties and functions, and contributed to the rapid expansion of our knowledge on renal epithelial cells. Recent findings led to a major appreciation of the significance of renal epithelial cell interactions with other cellular components of the kidney, and of the complexity of their response to the microenvironment. Sex-oriented studies have uncovered sex-specific differences in renal epithelial cells, boosting research interest on molecular, cellular and systems-based differences between males and females.

The aim of this Special Issue “Advances in Renal Epithelial Cells” is to assemble the latest studies highlighting the plurality of roles of renal epithelial cells in kidney health and disease. We welcome research papers and reviews, focusing on, but not exclusively, cellular and molecular mechanisms, use of biomaterials, precision medicine, patient-derived organoids and 3D models, animal models, therapeutic strategies and drug testing, single cell/nucleus RNA sequencing, multi-omics.

We hope that this special issue will provide a comprehensive understanding of renal epithelial cells, that will be of interest to both basic and clinician scientists.

Looking forward to receiving your contribution.

Dr. Anna Julie Peired
Dr. Laura Lasagni
Guest Editors

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