The Role of Adipose Tissue in Metabolic Diseases and Beyond
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 34556
Special Issue Editors
Interests: adipose tissue biology; BAT; WAT; lipid metabolism; oxidative stress; autophagy; cancer metabolism
Special Issues, Collections and Topics in MDPI journals
Interests: adipose tissue biology; metabolism, inflammation; epigenetics; neurodegeneration; cancer metabolism
Special Issues, Collections and Topics in MDPI journals
Interests: Adipose tissue biology, BAT, WAT; adipokines; hormonal signaling; nuclear receptors (Mineralocorticoid and glucocorticoid receptors)
Special Issue Information
Dear Colleagues,
From a tissue largely misunderstood as an inert depot of fat to be used in case of energy shortage, the role of adipose tissue in pathophysiology has been completely re-evaluated in the last decades. Adipose tissue controls the homeostasis of peripheral organs, but it has also been shown to establish a crosstalk with the central nervous system. Unlike other organs, adipose tissue is distributed throughout our body and there are different depots of adipocytes that perform specific functions, including energy balance for white adipocytes and thermoregulation for brown/beige adipocytes. In addition, adipocytes can adjust their phenotype and secrete a plethora of signalling molecules and metabolites in response to bioenergetic signals to control metabolic and inflammatory responses of neighbouring and distal organs. All these aspects justify the contribution of adipose tissue to a variety of metabolic disorders and pathological states.
This special issue aims to collect brief reports, research articles, reviews, and mini reviews on the biology of white adipose tissue (WAT) and brown adipose tissue (BAT) in the context of metabolic diseases and beyond. Topics concerning (but not limited to) metabolic and endocrine functions of BAT/WAT, browning and inflammation, in relation to obesity and diabetes as well as cancer and neurodegeneration, are welcome.
We look forward to receiving your contributions.
Prof. Dr. Maria Rosa Ciriolo
Dr. Fabio Ciccarone
Dr. Say Viengchareun
Guest Editors
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Keywords
- Adipose tissue biology
- BAT
- WAT
- Adipokines
- metabolic syndrome
- lipid metabolism
- endocrinology
- diabetes
- obesity
- inflammation
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