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Immune Biomarkers of Chronic Lung Diseases and Lung Cancer

This special issue belongs to the section “Cellular Immunology“.

Special Issue Information

Dear Colleagues,

The development of personalized medicine naturally forces a change in the diagnostic approach to lung cancer and chronic lung diseases, which is possible thanks to the discovery and study of biomarkers. Immunological biomarkers can create a characteristic picture of cellular features that can be used in therapy, but also for disease identification and evaluation of micrometastases or residual disease. With the recognition of new biomarkers, in cancer therapeutics, the past 5 years have seen something of a revolution in immunologically targeted approaches to treatment, including the development of a novel therapeutic drug class of immune checkpoint-blocking antibodies.  

With this in mind, many common respiratory diseases, including pneumonia, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and lung cancer require a new diagnostic perspective. There is evidence that COPD and pulmonary fibrosis are possibly complicated by lung cancer development and importantly change the course of pulmonary malignancies. Thus, the immune background of these conditions requires special attention.  

With the number of publications on immune biomarkers rapidly increasing, now is the time to take a broad perspective of the field, putting emphasis not only on the use of biomarkers to create new therapies, but also on improving diagnostics using immunological biomarkers.

Prof. Dr. Joanna Domagala-Kulawik
Dr. Agata Raniszewska
Dr. Iwona Kwiecień
Guest Editors

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Keywords

  • lung cancer
  • cell biomarkers
  • flow cytometry
  • antigen-specific assays
  • non-antigen-specific assays, Immune
  • chronic lung diseases COPD
  • interstitial lung diseases
  • asthma
  • rare lung diseases

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Cells - ISSN 2073-4409