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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Modern Neurosurgical Management of Gliomas

edited by

Arthur Wagner

and

Chiara Negwer

submission deadline 31 Dec 2025 | Viewed by 136 | Submission Open

Keywords: precision medicine; personalized oncological surgery; intraoperative imaging; fluorescence-guided surgery; intraoperative histopathology; liquid biopsy; minimally invasive oncological surgery; radiosurgery

(This special issue belongs to the Section Cancer Therapy)

Oncogenetics of Colorectal Cancer (2nd Edition)

edited by

Muhammad Kibriya

and Marc Bissonnette

submission deadline 31 Dec 2025 | Viewed by 125 | Submission Open

Keywords: colorectal carcinoma; somatic mutation; microsatellite instability; methylation; copy number change; tumor-infiltrating leukocyte; immune checkpoint inhibitor; drug resistance; cell-free DNA

(This special issue belongs to the Section Cancer Pathophysiology)

ALK in Cancer: Lessons from the Future (2nd Edition)

edited by

Petros Christopoulos

and

Richard Bayliss

submission deadline 31 Dec 2025 | Viewed by 121 | Submission Open

Keywords: ALK inhibitors; ALK fusion variants; TP53 mutations; immunotherapy; liquid biopsies; disease monitoring; therapeutic sequencing

(This special issue belongs to the Section Cancer Pathophysiology)

Leukemia Cell Signaling Pathways: Recent Advances, Future Perspectives, and Potential Clinical Applications

edited by

Bac Viet Le

and

Srinivas Chatla

submission deadline 31 Dec 2025 | Viewed by 110 | Submission Open

Keywords: leukemia; cell signaling; bone marrow microenvironment; leukemic transformation; drug resistance; therapeutic discovery; cell signaling inhibitors; precision medicine

(This special issue belongs to the Section Tumor Microenvironment)

Tumor Microenvironment of Gynecological Tumors

edited by

Zahid Pranjol

and

Dmitry Aleksandrovich Zinovkin

submission deadline 10 Jan 2026 | 2 articles | Viewed by 1424 | Submission Open

Keywords: tumor microenvironment; gynecological cancers; immunomodulation; cancer-associated fibroblasts; angiogenesis; cancer-like stem cells; extracellular matrix; immune evasion; cell signaling; therapeutics

(This special issue belongs to the Section Tumor Microenvironment)

The Role of Flow Cytometry in Hematologic Malignancies

edited by

Kristy Wolniak

and Lucy Fu

submission deadline 12 Jan 2026 | Viewed by 199 | Submission Open

Keywords: flow cytometry; hematology; oncology; malignancy; lymphoma; leukemia; pathology; innovation; methodology; diagnosis

(This special issue belongs to the Section Methods and Technologies Development)

Neoadjuvant Therapy of Breast Cancer

edited by

Hiroyuki Takei

and Takaaki Fujii

submission deadline 15 Jan 2026 | 9 articles | Viewed by 23082 | Submission Open

Keywords: neoadjuvant systemic therapy; chemotherapy; endocrine therapy; molecular targeted therapy; molecular subtypes; response-guided therapy; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Cervical Cancer: Study on Molecular Landscape and Protein Biomarkers. Current Diagnostic and Therapeutic Capabilities

edited by

Christopher Kobierzycki

and

Piotr Dzięgiel

submission deadline 15 Jan 2026 | 7 articles | Viewed by 14239 | Submission Open

Keywords: cervical cancer; cervical dysplasia; human papilloma virus (HPV); tumor markers; cancerogenesis; genotyping

(This special issue belongs to the Section Molecular Cancer Biology)

Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs)

edited by Wei Chen, Fei Li and

Qiang Jeremy Wen

submission deadline 15 Jan 2026 | 4 articles | Viewed by 9165 | Submission Open

Keywords: MPNs; ET; PV; PMF; post-PV-MF; post-ET-MF; MDS/MPN; JAK2

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical and Research Progress in the Resection of Gastro-Esophageal Cancer

edited by Biniam Kidane

submission deadline 15 Jan 2026 | 5 articles | Viewed by 8918 | Submission Open

(This special issue belongs to the Section Clinical Research of Cancer)

Recent Advances in Liquid Biopsy Biomarkers of Cancer

edited by

Hua-Jun He

submission deadline 15 Jan 2026 | 3 articles | Viewed by 2981 | Submission Open

Keywords: liquid biopsy; circulating tumor cells; circulating tumor DNA; extracellular vesicles; circulating RNA; cfDNA methylation; fragmentome; reference material; miRNA; multi-cancer detection

(This special issue belongs to the Section Cancer Biomarkers)

Cell Biology of Cancer Invasion: 2nd Edition

edited by

Hideki Yamaguchi

submission deadline 15 Jan 2026 | 2 articles | Viewed by 2544 | Submission Open

Keywords: invasion; metastasis; intravasation; extravasation; invadopodia; tumor microenvironment; epithelial– mesenchymal transition; cell migration; cytoskeleton; cell adhesion; extracellular matrix; matrix metalloprotease; cancer-associated fibroblast; tumor-associated macrophage

(This special issue belongs to the Section Cancer Metastasis)

Circulating Tumour DNA and Liquid Biopsy in Oncology

edited by

Yafeng Ma

and Kevin Spring

submission deadline 15 Jan 2026 | 2 articles | Viewed by 2078 | Submission Open

Keywords: cell-free DNA; circulating tumour DNA; liquid biopsy; mutation status; tumour mutational burden; methylation detection; fragmentomics; minimal residual disease; early detection

(This special issue belongs to the Section Cancer Biomarkers)

The Survival of Colon and Rectal Cancer (2nd Edition)

edited by

Susanne Merkel

submission deadline 15 Jan 2026 | 1 articles | Viewed by 1035 | Submission Open

Keywords: colorectal cancer; colorectal cancer surgery; multidisciplinary treatment; survival; prognostic factors; distant metastasis; locoregional recurrences; standardisation; individualisation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Updates on Urothelial Carcinoma

edited by

Toyonori Tsuzuki

and Yasmin Abu-Ghanem

submission deadline 15 Jan 2026 | Viewed by 228 | Submission Open

Keywords: urothelial carcinoma; systemic therapy; molecular biomarkers; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Pediatric Cancer Research from Basic Biology to Experimental Therapy

edited by

Atif Ahmed

submission deadline 16 Jan 2026 | 3 articles | Viewed by 10806 | Submission Open

Keywords: pediatric tumors; solid cancers; leukemias; cancer predisposition syndromes; genetics; omics; immunotherapy; therapy resistance

(This special issue belongs to the Section Pediatric Oncology)

Survivorship Following Childhood, Adolescent and Young Adult Cancer

edited by Magdalena Balcerek and Judith Gebauer

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2278 | Submission Open

Keywords: cancer survivorship; late effects; long-term follow-up care; supportive care; health prevention and promotion

(This special issue belongs to the Section Pediatric Oncology)

Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle

edited by

Hiroaki Kiyokawa

submission deadline 20 Jan 2026 | Viewed by 297 | Submission Open

Keywords: cell cycle; signaling pathway; precision medicine

(This special issue belongs to the Section Molecular Cancer Biology)

Recent Trends in the Development of Theranostics and Multifunctional Tracers in Oncology

edited by

Olaf Prante

submission deadline 20 Jan 2026 | Viewed by 167 | Submission Open

Keywords: multifunctional radiopharmaceuticls; PET/CT; multimodal imaging; cancer treatment

(This special issue belongs to the Section Methods and Technologies Development)

The Prospect of Nanobiotechnology in Cancers

edited by

Wenpan Li

submission deadline 20 Jan 2026 | Viewed by 157 | Submission Open

Keywords: nanobiotechnology; cancer therapy; targeted drug delivery; tumor microenvironment

(This special issue belongs to the Section Methods and Technologies Development)

Recent Updates on Imaging and Staging of Gynecologic Cancers

edited by

David Mutch

and Alexander B. Olawaiye

submission deadline 21 Jan 2026 | 2 articles | Viewed by 2294 | Submission Open

Keywords: imaging; surgical staging; molecular prognostic features; mortality; prognosis

(This special issue belongs to the Section Methods and Technologies Development)

Roles of the Tumor Microenvironment on Liquid Biopsy (2nd Edition)

edited by

Dario Marchetti

submission deadline 22 Jan 2026 | Viewed by 305 | Submission Open

Keywords: liquid biopsy; CTCs; CTC characterization and CTC clustering; ctDNA and ctDNA profiling; exosomes/extracellular vesicles and biology; tumor microenvironment; bone marrow cellular/molecular heterogeneity; CTCs/blood/BM cells crosstalk; analytical validity; clinical validity; and clinical utility of liquid biopsy; liquid biopsy interplaying dormancy and metastasis

(This special issue belongs to the Section Tumor Microenvironment)

Advancements in Salivary Gland Tumors Management: From Diagnostic Imaging to Treatment Strategies

edited by Wioletta Pietruszewska, Małgorzata Wierzbicka and

Boguslaw Mikaszewski

submission deadline 22 Jan 2026 | Viewed by 230 | Submission Open

Keywords: salivary gland tumors; MRI; CT; and PET; minimally invasive approaches

(This special issue belongs to the Section Cancer Therapy)

Innovative Immunotherapies: CAR-T Cell Therapy for Cancers: 2nd Edition

edited by

Shebli Atrash

submission deadline 23 Jan 2026 | 3 articles | Viewed by 5363 | Submission Open

Keywords: CAR-T; NK-CAR; immunotherapy; cancer; resistance mechanisms

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Targeting Hallmarks of Cancer

edited by

Carlos Pérez Plasencia

submission deadline 25 Jan 2026 | Viewed by 722 | Submission Open

Keywords: epigenetic regulators; organotypic culture models; anticancer drugs; hallmarks of cancer

(This special issue belongs to the Section Cancer Biomarkers)

Towards a Personalized Medicine for the Diagnosis and Management of Gynecological Cancers

edited by

Diego Raimondo

and Gabriele Centini

submission deadline 30 Jan 2026 | 3 articles | Viewed by 19595 | Submission Open

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

The Advance of Pencil Beam Scanning Proton Beam Therapy in Cancers

edited by

Haibo Lin

, Richard A. Amos and Heng Li

submission deadline 30 Jan 2026 | 7 articles | Viewed by 15252 | Submission Open

Keywords: proton therapy; pencil beam scanning; robustness; adaptive radiotherapy; imaging guidance; radiobiological model; FLASH radiotherapy; spatially fractionated radiotherapy (SFRT); proton arc

(This special issue belongs to the Section Cancer Therapy)

Cancer Disparities: Biological, Social, and Environmental Determinants

edited by

Riffat Mehboob

and

Miguel Muñoz

submission deadline 30 Jan 2026 | 3 articles | Viewed by 5588 | Submission Open

Keywords: cancer epidemiology; cancer etiology; environmental factors; screening and diagnostics; SDGs

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in the Treatment of Upper Gastrointestinal Cancer

edited by Sang-ho Jeong and

Jae-seok Min

submission deadline 30 Jan 2026 | 2 articles | Viewed by 4359 | Submission Open

Keywords: upper gastrointestinal cancer; surgery therapy; chemotherapy therapy; radiation therapy

(This special issue belongs to the Section Cancer Therapy)

Protein Structure and Cancer—2nd Edition

edited by

Michalis Aivaliotis

submission deadline 30 Jan 2026 | Viewed by 185 | Submission Open

Keywords: protein structure dynamics; structural cancer biology; protein pathways in cancer; structure– function alterations; in silico protein structure prediction; protein interactions; cancer mutations and protein structure alterations

(This special issue belongs to the Section Molecular Cancer Biology)

Metastasis in Tumor Immunity: Current Perspectives

edited by

Ulrike Stein

, Sebastian Torke and

Wolfgang Walther

submission deadline 30 Jan 2026 | Viewed by 183 | Submission Open

Keywords: immune escape; immune evasion; immune microenvironment; intervention strategies; senescence on metastasis; anti-tumor immunity; cellular interactions; molecular interactions; immune suppression; immune checkpoints

(This special issue belongs to the Section Cancer Metastasis)

Advances in Drug Delivery for Cancer Therapy

edited by

Ashakumary Lakshmikuttyamma

submission deadline 31 Jan 2026 | 9 articles | Viewed by 36187 | Submission Open

Keywords: cancer; oncology; therapeutic target; drug resistance; immunotherapy; chemotherapy; small molecule inhibitors; drug delivery; nanoparticle

(This special issue belongs to the Section Cancer Drug Development)

How COVID-19 Affects Cancer Patients

edited by

Maria Fiore

submission deadline 31 Jan 2026 | 15 articles | Viewed by 33463 | Submission Open

Keywords: COVID-19; pandemic; cancer; impact; incidence; mortality; lethality; disparities; gender

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Surgical Advances in Cancer Treatments: Exploring Innovative Approaches and Emerging Perspectives

edited by

and

submission deadline 31 Jan 2026 | 16 articles | Viewed by 28831 | Submission Open

Keywords: surgical oncology; surgical innovation; image-guided surgery; robotic-assisted surgery; multidisciplinary oncology; surgical outcomes research; precision surgery; healthcare economics; surgical training and simulation

(This special issue belongs to the Section Cancer Therapy)

Genetics and Epigenetics of Gynecological Cancer

edited by

Carmela De Marco

submission deadline 31 Jan 2026 | 10 articles | Viewed by 28103 | Submission Open

Keywords: gynecologic cancers; epigenetics; genetics; immunogenetics; predisposing mutations; biomarkers; targeted therapies; chemoresistance

(This special issue belongs to the Section Cancer Pathophysiology)

CAR T Cells in Lymphoma and Multiple Myeloma

edited by

Javier Munoz

and

Julia Erin Wiedmeier-Nutor

submission deadline 31 Jan 2026 | 7 articles | Viewed by 21218 | Submission Open

Keywords: multiple myeloma; lymphoma; CAR T therapy; bi-specific antibodies; cellular therapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Screening, Early Detection and Prevention of Hepato-Pancreato-Biliary (HPB) Cancers

edited by Zaed Z.R. Hamady

submission deadline 31 Jan 2026 | 7 articles | Viewed by 21004 | Submission Open

Keywords: hepatobiliary cancer; pancreatic cancer; early detection; diagnosis; screening; prevention

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Emerging Research on Primary Brain Tumors

edited by Jacob S Young and Mitchel S. Berger

submission deadline 31 Jan 2026 | 6 articles | Viewed by 15074 | Submission Open

Keywords: molecular biomarkers; drug delivery; immunotherapy; personalized medicine; targeted therapies; glioma

(This special issue belongs to the Section Cancer Therapy)

Thyroid Cancer: Diagnosis, Prognosis and Treatment (2nd Edition)

edited by

Luca Giovanella

and

Petra Petranović Ovčariček

submission deadline 31 Jan 2026 | 8 articles | Viewed by 14535 | Submission Open

Keywords: thyroid cancer; ultrasound; molecular imaging; fine-needle aspiration cytology; thyroidectomy; radioactive iodine; radioiodine-refractory thyroid cancer; tyrosine kinase inhibitors

(This special issue belongs to the Section Cancer Therapy)

Empowering Cancer Survivors: A Comprehensive Approach to Supportive Care Through Pharmacological and Non-Pharmacological Approaches Including Exercise, Physical Activity and Nutrition

edited by Kellie Toohey

submission deadline 31 Jan 2026 | 10 articles | Viewed by 11402 | Submission Open

Keywords: cancer; physical activity; exercise; supportive care; holistic care; rehabilitation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Pathology and Treatment of Triple-Negative Breast Cancer

edited by

Ramadevi Subramani

submission deadline 31 Jan 2026 | 4 articles | Viewed by 11211 | Submission Open

(This special issue belongs to the Section Cancer Pathophysiology)

Implementation of Physical Activity Promotion in Cancer Care

edited by Sarah Hardcastle

submission deadline 31 Jan 2026 | 4 articles | Viewed by 9846 | Submission Open

Keywords: physical activity; cancer survivors; behaviour change; interventions; cancer care; implementation; health

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

The Tumor Microenvironment: Interplay Between Immune Cells

edited by Jared Rowe and Kristen E. Pauken

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9153 | Submission Open

Keywords: tumor immune microenvironment; metabolic microenvironment; immune cells

(This special issue belongs to the Section Tumor Microenvironment)

Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition

edited by

Antonio Piñero-Madrona

submission deadline 31 Jan 2026 | 6 articles | Viewed by 7619 | Submission Open

Keywords: breast cancer surgery; axillary management; sentinel node oncoplastic surgery; reconstructive surgery; surgical technology; cancer risk reduction surgery; radio-guided surgery

(This special issue belongs to the Section Cancer Therapy)

Recent Advances in Oncology Imaging: 2nd Edition

edited by

Li Liu

and

Yicheng Ni

submission deadline 31 Jan 2026 | 4 articles | Viewed by 7403 | Submission Open

Keywords: medical imaging; cancer; oncology; molecular imaging; theragnostics

(This special issue belongs to the Section Methods and Technologies Development)

Biomarkers and Targeted Therapy in Malignant Pleural Mesothelioma

edited by

Susana Cedrés

submission deadline 31 Jan 2026 | 2 articles | Viewed by 5339 | Submission Open

Keywords: malignant mesothelioma; target therapy; biomarkers

(This special issue belongs to the Section Cancer Biomarkers)

The Role of Apoptosis and Autophagy in Cancer

edited by

Souren Paul

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4693 | Submission Open

Keywords: apoptosis; cell death; tumor

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Lung Ultrasound in Cancer Patients

edited by Helmut Prosch and

Ehsan Safai Zadeh

submission deadline 31 Jan 2026 | 4 articles | Viewed by 4421 | Submission Open

Keywords: lung ultrasound; neoplastic pleuro-pulmonary lesions; lung cancer; oncologic imaging; ultrasound; CEUS; elastography

(This special issue belongs to the Section Methods and Technologies Development)

Exploring Skin Cancer: Insights into New Diagnostic, Prognostic, and Therapeutic Strategies

edited by

Emi Dika

submission deadline 31 Jan 2026 | 4 articles | Viewed by 4288 | Submission Open

Keywords: melanoma; non-melanoma skin cancer; NMSC; Merkel cell carcinoma; tumor microenvironment; prognosis; treatment

Cancer Screening and Primary Care

edited by Marievelisse Soto-Salgado

submission deadline 31 Jan 2026 | 5 articles | Viewed by 4205 | Submission Open

Keywords: screening amenable cancers; screening; primary care; disparities in cancer care; cancer outcomes

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Displaying special issue 251-300 on page 6 of 24.

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