Tumor Microenvironment and Pancreatic Cancer

Dear Colleagues,

We are pleased to invite you or your promising young colleague to make a valuable contribution to the Special Issue of Cancers titled “Tumor Microenvironment and Pancreatic Cancer”.

Pancreatic cancer is increasing in prevalence worldwide, and is one of the most lethal malignancies, with a 5 year survival of around 9%. The most common type, pancreatic ductal adenocarcinoma (PDAC), is histologically characterized by an abundant stromal component with marked fibrosis and hypovascularity; this tumor microenvironment appears to be highly involved in the pathological condition as well as the catastrophic prognosis. Recently, diversity and heterogeneity in the tumor microenvironment of PDAC are attracting attention. There seem to be a variety of non-cancer cells with pro-tumor and anti-tumor functions, and therefore a more detailed understanding of the complicated microenvironment might be required in order to advance efforts in controlling and conquering PDAC.

This Special Issue aims to bring together the current findings and opinions in many aspects of the tumor microenvironment of PDAC to provide clues for the future directions in this field.

Original research articles and reviews are welcome in this Special Issue. Research areas may include (but are not limited to) the following: pathogenesis, early diagnosis, potential therapeutic strategy, therapeutic resistance, and biomarkers in basic, clinical, and translational research, related with tumor microenvironment of PDAC. This information exchange will help to make great progress in our understanding of this disease and in improving the prognosis.

We look forward to receiving your contributions.

Dr. Hideaki Ijichi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.