Special Issue "Cancer Chemotherapy Resistance"
Deadline for manuscript submissions: 15 December 2023 | Viewed by 3594
Interests: toxicology; basic oncology; cancer drug resistance; novel anti-cancer compounds
Special Issues, Collections and Topics in MDPI journals
Chemotherapy remains one of the most successful therapeutic approaches to cancer treatment. It uses anti-cancer drugs with different modes of action to destroy cancer cells. The major problems of chemotherapy are the development of cancer drug resistance and side effects. Tumours may be intrinsically drug-resistant or develop resistance to chemotherapy during this treatment, and acquired resistance is especially a particular problem. Tumours become resistant to used drugs but may also become cross-resistant to other drugs with different mechanisms of action. Even though different anti-cancer drugs have been in clinical use for more than forty years and represent one of the major topics of investigation in cancer research, the problem of drug resistance remains unsolved. To date, there are many molecular mechanisms that are thought to be involved in drug resistance, such as decreased drug uptake, increased drug inactivation, alterations in drug targets, the processing of drug-induced damages, and cell death escape.
This Special Issue will focus on the characterisation of novel molecular mechanisms, the signalling pathways involved in regulating tumour response to chemotherapy, and novel targets which can combat drug resistance. Our main aim is to predict responses to chemotherapy and modulate these responses with targeted therapies with the goal of selecting the best treatment for individual patients.
Dr. Anamaria Brozovic
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- drug resistance
- molecular mechanisms
- signalling pathways