Sarcomas: New Biomarkers and Therapeutic Strategies

Dear colleagues,

Bone and soft tissue sarcoma are heterogeneous diseases comprised of various molecular and histologic subtypes. During the 1980s and 1990s, due to the advancement of chemotherapy and surgical technique, the survival rate reached approximately 70–80% in patients with sarcoma. However, survival rates have not improved during the last 30 years. New biomarkers and therapeutic strategies are necessary to further improve the prognosis. In this issue, the authors describe possible biomarkers for predicting the prognosis of sarcomas. The enormous value of biomarkers should also be emphasized, above all of their ability to vary expression levels during disease progression and in response to the treatment. New drugs may be developed when those biomarkers are targeted. The aim of the Special Issue is to investigate new biomarkers and their possible application for the treatment in patients with sarcoma.

Dr. Tomoki Nakamura
Guest Editor

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