Epidemiology of Hepatocellular Carcinoma
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Causes, Screening and Diagnosis".
Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 6663
Special Issue Editors
Interests: liver carcinogenesis; cancer chemoprevention; chronic hepatitis; metabolic syndrome; retinoid; phytochemicals; clinical trial
Special Issues, Collections and Topics in MDPI journals
Interests: cancer prevention; gastroenterological disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hepatocellular carcinoma (HCC) is one of the most common malignancies and the major leading cause of cancer mortality worldwide. Eastern Asia and Africa in particular have the highest prevalence of HCC, while its incidence and mortality in the United States and Europe are also increasing. Risk factors for HCC include persistent infections of hepatitis B virus (HBV) and hepatitis C virus (HCV), excess alcohol consumption, non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH), obesity, and type 2 diabetes. Due to the prevention of HBV/HCV infections and control of chronic viral hepatitis, the underlying etiology of HCC is changing from hepatitis viruses, and the proportion of cases caused by NAFLD/NASH has recently been rising. It is important to accurately grasp current epidemiological trends and to establish optimal surveillance for HCC. In addition, studies to elucidate the mechanisms involved in liver carcinogenesis and to develop the methods for preventing HCC are required.
In this Special Issue, we will publish original research and review articles focusing on the epidemiology, risk factors, and prevention of HCC as well as mechanism of liver carcinogenesis.
Prof. Dr. Masahito Shimizu
Dr. Yohei Shirakami
Guest Editors
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Keywords
- epidemiology
- hepatitis B virus or HBV
- hepatitis C virus or HCV
- hepatocellular carcinoma or HCC
- liver carcinogenesis
- liver cirrhosis
- liver fibrosis
- NAFLD
- NASH
- prevention
- surveillance
- tumor markers
- viral hepatitis
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