Advances in Cancer Cachexia
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 15309
Special Issue Editors
Interests: cancer cachexia
Interests: cancer cachexia; nutrition
Special Issue Information
Dear Colleagues,
Cachexia is an impactful complication of cancer with pronounced effects on patient survival and quality of life. Despite this, there has been limited progress in the identification of factors that play a role in the pathogenesis of cachexia and can serve as treatment targets. This is largely due to a lack of experimental research models able to accurately mimic human disease and challenges in diagnosing relevant aspects of cachexia.
In this Special Issue of Cancers, we aim to publish a collection of manuscripts that further our understanding of cancer cachexia and provide novel approaches of assessing cachexia severity, thereby advancing our insights into the factors that play a role in its development and enabling clinical trials with better cachexia phenotyping. In particular, we are looking for papers that describe:
- Development of novel translational models of cancer cachexia (e.g., organoids or new mouse models with slower cachexia progression);
- The role of inflammation and immune cell activation in cancer cachexia;
- The role of the liver and of insulin resistance in cancer cachexia;
- Myosteatosis and other body composition changes in patients with cancer cachexia;
- Artificial intelligence-based approaches to body composition analysis;
- Use of wearables to assess cachexia severity;
- Relationship between body composition and immunotherapy outcomes;
- Prehabilitation approaches to improve therapeutic outcome of cachectic patients.
We are inviting the submission of original or review articles on these topics; however, we will also consider other high-quality cancer-cachexia-related papers.
Sincerely,
Dr. Sander S. Rensen
Prof. Dr. Steven W. M. Olde Damink
Dr. David P.J. Van Dijk
Guest Editors
Manuscript Submission Information
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Keywords
- myosteatosis
- inflammation
- body composition
- prehabilitation
- translational models
- organoids
- insulin resistance
- cachexia phenotypes
- tumor-organ crosstalk
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