Targeting the Tumor Microenvironment (Volume II)

Dear Colleagues,

This collection is the second edition of the Special Issue “Targeting the Tumor Microenvironment” (https://www.mdpi.com/journal/cancers/special_issues/TME).

The tumor microenvironment (TME) plays a pivotal role in different types of cancer. The interactions that occur within the TME are fundamental in tumor-induced suppression of the immune system and metastatic dissemination of cancer cells, and these mechanisms may ultimately affect tumor progression and treatment outcomes. Recently introduced cancer therapies target the interaction between tumors and the TME. However, stromal components of the tumor niche may extensively affect drug response in tumor cells. Furthermore, stroma-targeted strategies have emerged as a new treatment option for many types of cancer. Despite the recent advances in cancer treatment, a proportion of patients remain resistant. Thus, it is necessary to develop innovative therapeutic approaches by investigating the fundamental role of TME. We invite authors to contribute cutting-edge studies to this Special Issue, entitled “Targeting the Tumor Microenvironment (Volume II)”, to further highlight the involvement of TME in cancer progression and treatment.

Prof. Dr. Georgios Giamas
Prof. Dr. Teresa Gagliano
Guest Editors

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