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28 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Transplant Oncology


We are delighted to share a collection of highly viewed papers on transplant oncology that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

The list of relevant papers can be seen below:

“Evolving Indications for Liver Transplantation for Hepatocellular Carcinoma Following the Milan Criteria”
by Takashi Kokudo and Norihiro Kokudo
Cancers 2025, 17(3), 507; https://doi.org/10.3390/cancers17030507
Available online: https://www.mdpi.com/2072-6694/17/3/507

“The Role of Organoids in Advancing Colorectal Cancer Research: Insights and Future Directions”
by Zahra Heydari, Rex Devasahayam Arokia Balaya, Gobinda Sarkar and Lisa Boardman
Cancers 2025, 17(13), 2129; https://doi.org/10.3390/cancers17132129
Available online: https://www.mdpi.com/2072-6694/17/13/2129

“HepatoPredict Accurately Selects Hepatocellular Carcinoma Patients for Liver Transplantation Regardless of Tumor Heterogeneity”
by Rita Andrade, Judith Perez-Rojas, Sílvia Gomes da Silva, Migla Miskinyte, Margarida C. Quaresma, Laura P. Frazão, Carolina Peixoto, Almudena Cubells, Eva M. Montalvá, António Figueiredo et al.
Cancers 2025, 17(3), 500; https://doi.org/10.3390/cancers17030500
Available online: https://www.mdpi.com/2072-6694/17/3/500

“The Applications of Machine Learning in the Management of Patients Undergoing Stem Cell Transplantation: Are We Ready?”
by Luca Garuffo, Alessandro Leoni, Roberto Gatta and Simona Bernardi
Cancers 2025, 17(3), 395; https://doi.org/10.3390/cancers17030395
Available online: https://www.mdpi.com/2072-6694/17/3/395

“cfDNA Chimerism and Somatic Mutation Testing in Early Prediction of Relapse After Allogeneic Stem Cell Transplantation for Myeloid Malignancies”
by Scott D. Rowley, Maher Albitar, Melissa F. Baker, Alaa Ali, Sukhdeep Kaur, Hyung C. Suh, Andre Goy and Michele L. Donato
Cancers 2025, 17(4), 625; https://doi.org/10.3390/cancers17040625
Available online: https://www.mdpi.com/2072-6694/17/4/625

“Post-Transplant Cyclophosphamide-Based Prophylaxis and Its Impact on Infectious Complications and Immune Reconstitution According to Donor Type”
by Beatriz Merchán-Muñoz, María Suárez-Lledó, Luis Gerardo Rodríguez-Lobato, Tommaso Francesco Aiello, Antonio Gallardo-Pizarro, Paola Charry, Joan Cid, Miquel Lozano, Alexandra Pedraza, Alexandra Martínez-Roca et al.
Cancers 2025, 17(7), 1109; https://doi.org/10.3390/cancers17071109
Available online: https://www.mdpi.com/2072-6694/17/7/1109

Special Issues:
“Advances and Future Developments in Liver Transplantation for Cancers: 2nd Edition”
Guest Editor: Dr. Nicolas Golse
Submission deadline: 31 January 2026
“Current Use of Hematopoietic Cell Transplantation in Hematologic Malignancies”
Guest Editors: Dr. Marina Díaz-Beyá and Dr. Maria Queralt Salas
Submission deadline: 31 March 2026

“Immunotherapy and Transplantation in the Era of Transplant Oncology (2nd Edition)”
Guest Editor: Dr. Maen Abdelrahim
Submission deadline: 20 April 2026
“Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) in Patients with Cancers”
Guest Editors: Dr. Caterina Alati and Dr. Martina Pitea
Submission deadline: 31 July 2026

You can view and submit relevant papers to Cancers via the following link: https://www.mdpi.com/journal/cancers.

Cancers Editorial Office

28 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Cancer Survivorship and Quality of Life


We are delighted to share a collection of highly viewed papers on cancer survivorship and quality of life  that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

The list of relevant papers can be seen below:

“From Diagnosis to Survivorship: The Role of Social Determinants in Cancer Care”
by
Abiha Abdullah, Zeyu Liu and Michele Molinari
Cancers 2025, 17(7), 1067; https://doi.org/10.3390/cancers17071067
Available online: https://www.mdpi.com/2072-6694/17/7/1067

“Sleep and Cancer”
by Courtney M. Vaughn and Bradley V. Vaughn
Cancers 2025, 17(6), 911; https://doi.org/10.3390/cancers17060911
Available online: https://www.mdpi.com/2072-6694/17/6/911

“Right-Sided Versus Left-Sided Colon Cancer—A 5-Year Single-Center Observational Study”
by
Julia Szostek, Michał Serafin, Magdalena Mąka, Beata Jabłońska and Sławomir Mrowiec
Cancers 2025, 17(3), 537; https://doi.org/10.3390/cancers17030537
Available online: https://www.mdpi.com/2072-6694/17/3/537

“Malignant Bowel Occlusion: An Update on Current Available Treatments”
by Benedetto Neri, Nicolò Citterio, Sara Concetta Schiavone, Dario Biasutto, Roberta Rea, Margareth Martino and Francesco Maria Di Matteo
Cancers 2025, 17(9), 1522; https://doi.org/10.3390/cancers17091522
Available online: https://www.mdpi.com/2072-6694/17/9/1522 

“Initial Use Experience of Durvalumab Plus Gemcitabine and Cisplatin for Advanced Biliary Tract Cancer in a Japanese Territory Center”
by Kento Shionoya, Atsushi Sofuni, Shuntaro Mukai, Yoshiya Yamauchi, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Kenjiro Yamamoto, Kazumasa Nagai, Yukitoshi Matsunami et al.
Cancers 2025, 17(2), 314; https://doi.org/10.3390/cancers17020314
Available online: https://www.mdpi.com/2072-6694/17/2/314

“Fatigue Level Associated with Quality of Life for Prostate Cancer Patients: Results from the All of Us Research Program”
by Hui-Yi Lin, Masuma Mannan, Yu-Wen Chiu, Ya-Hsin Li, Rajasree P. Chowdry and Tung-Sung Tseng
Cancers 2025, 17(9), 1531; https://doi.org/10.3390/cancers17091531
Available online: https://www.mdpi.com/2072-6694/17/9/1531

Special Issues:

“Implementation of Physical Activity Promotion in Cancer Care”
Guest Editor: Dr. Sarah Hardcastle
Submission deadline: 31 January 2026

“Exercise Interventions for People Living with Cancer: Advances in Knowledge and Implementation”
Guest Editors: Dr. Lara Edbrooke and Dr. Chris Swain
Submission deadline: 31 March 2026

“Rehabilitation Opportunities in Cancer Survivorship”
Guest Editors: Dr. Marie Carmen Valenza and Dr. Alejandro Heredia-Ciuro
Submission deadline: 8 May 2026
“Nursing and Supportive Care for Cancer Survivors”
Guest Editor: Dr. Michela Piredda
Submission deadline: 12 June 2026

You can view and submit relevant papers to Cancers via the following link: https://www.mdpi.com/journal/cancers.

Cancers Editorial Office

28 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Molecular Cancer Biology


We are delighted to share a collection of highly viewed papers on molecular cancer biology that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you.

The list of relevant papers can be seen below:

“Repeated COVID-19 Vaccination as a Poor Prognostic Factor in Pancreatic Cancer: A Retrospective, Single-Center Cohort Study”
by Makoto Abue, Mai Mochizuki, Rie Shibuya-Takahashi, Kensuke Ota, Yuta Wakui, Wataru Iwai, Jun Kusaka, Masashi Saito, Shinichi Suzuki, Ikuro Sato et al.
Cancers 2025, 17(12), 2006; https://doi.org/10.3390/cancers17122006
Available online: https://www.mdpi.com/2072-6694/17/12/2006

“Reduction of Prostate Cancer Risk: Role of Frequent Ejaculation-Associated Mechanisms”
by Mohamed Hassan, Thomas W. Flanagan, Abdulaziz M. Eshaq, Osama K. Altamimi, Hassan Altalag, Mohamed Alsharif, Nouf Alshammari, Tamadhir Alkhalidi, Abdelhadi Boulifa, Siraj M. El Jamal et al.
Cancers 2025, 17(5), 843; https://doi.org/10.3390/cancers17050843
Available online: https://www.mdpi.com/2072-6694/17/5/843

“The Role of KRAS Mutations in Colorectal Cancer: Biological Insights, Clinical Implications, and Future Therapeutic Perspectives”
by Mitsunobu Takeda, Shoma Yoshida, Takuya Inoue, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mamoru Uemura, Hirofumi Yamamoto et al.
Cancers 2025, 17(3), 428; https://doi.org/10.3390/cancers17030428
Available online: https://www.mdpi.com/2072-6694/17/3/428

“Heterogeneity in Cancer”
by William J. MacDonald, Connor Purcell, Maximilian Pinho-Schwermann, Nolan M. Stubbs, Praveen R. Srinivasan and Wafik S. El-Deiry
Cancers 2025, 17(3), 441; https://doi.org/10.3390/cancers17030441
Available online: https://www.mdpi.com/2072-6694/17/3/441

“Molecular Insights on Signaling Cascades in Breast Cancer: A Comprehensive Review”
by Venketesh K. Panda, Barnalee Mishra, Samikshya Mahapatra, Biswajit Swain, Diksha Malhotra, Suryendu Saha, Sinjan Khanra, Priyanka Mishra, Sambhunath Majhi, Kavita Kumari et al.
Cancers 2025, 17(2), 234; https://doi.org/10.3390/cancers17020234
Available online:  https://www.mdpi.com/2072-6694/17/2/234

“Deciphering the Role of Cancer Stem Cells: Drivers of Tumor Evolution, Therapeutic Resistance, and Precision Medicine Strategies”
by Mohamed El-Tanani, Syed Arman Rabbani, Shakta Mani Satyam, Imran Rashid Rangraze, Adil Farooq Wali, Yahia El-Tanani and Alaa A. A. Aljabali
Cancers 2025, 17(3), 382; https://doi.org/10.3390/cancers17030382
Available online:  https://www.mdpi.com/2072-6694/17/3/382

Special Issues:

Growth Factors and Receptor Tyrosine Kinases in Development, Regeneration, and Tumorigenesis (2nd Edition)
Guest Editor: Prof. Dr. Carl-Henrik Heldin
Submission deadline: 30 November 2025

PTEN: Regulation, Signalling and Targeting in Cancer
Guest Editors: Dr. Éric Chastre, Dr. Larissa Kotelevets and Dr. Mark G. H. Scott
Submission deadline: 31 December 2025

Heterogeneity in Intra-Cranial Tumors: Diagnostic, Prognostic, and Therapeutic Implications
Guest Editors: Prof. Dr. Francois Ducray, Dr. Shawn L. Hervey-Jumper and Dr. Thiebaud Picart
Submission deadline: 28 February 2026

Mitochondrial Metabolism and Cancer
Guest Editor: Prof. Dr. Marcos Roberto de Oliveira
Submission deadline: 31 July 2026

We hope this announcement will provide useful information for the field of molecular cancer biology.

23 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Tumor Microenvironment


We are delighted to share a collection of highly viewed papers in tumor microenvironment that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

The list of relevant papers can be seen below:

Richness for Tumor-Infiltrating B-Cells in the Oral Cancer Tumor Microenvironment Is a Prognostic Factor in Early-Stage Disease and Improves Outcome in Advanced-Stage Disease
by Irene H. Nauta, Dennis N. L. M. Nijenhuis, Sonja H. Ganzevles, Pamela I. Raaff, Jan Kloosterman, Elisabeth Bloemena, Ruud H. Brakenhoff, C. René Leemans and Rieneke van de Ven
Cancers 2025, 17(1), 113; https://doi.org/10.3390/cancers17010113
Available online: https://www.mdpi.com/2072-6694/17/1/113

“A Novel In Vitro Model of the Bone Marrow Microenvironment in Acute Myeloid Leukemia Identifies CD44 and Focal Adhesion Kinase as Therapeutic Targets to Reverse Cell Adhesion-Mediated Drug Resistance”
by Eleni E. Ladikou, Kim Sharp, Fabio A. Simoes, John R. Jones, Thomas Burley, Lauren Stott, Aimilia Vareli, Emma Kennedy, Sophie Vause and Timothy Chevassut et al.
Cancers 2025, 17(1), 135; https://doi.org/10.3390/cancers17010135
Available online: https://www.mdpi.com/2072-6694/17/1/135

“Metabolic Signaling in the Tumor Microenvironment”
by Ryan Clay, Kunyang Li and Lingtao Jin
Cancers 2025, 17(1), 155; https://doi.org/10.3390/cancers17010155
Available online: https://www.mdpi.com/2072-6694/17/1/155

“SSTR2-Targeted Theranostics in Hepatocellular Carcinoma”
by Majid Momeny, Solmaz AghaAmiri, Servando Hernandez Vargas, Belkacem Acidi, Sukhen C. Ghosh, Tyler M. Bateman, Jack T. Adams, Vahid Khalaj, Ahmed O. Kaseb, Hop S. Tran Cao et al.
Cancers 2025, 17(2), 162; https://doi.org/10.3390/cancers17020162
Available online: https://www.mdpi.com/2072-6694/17/2/162

“Differential Response to Local Stimulator of Interferon Genes Agonist Administration in Tumors with Various Stimulator of Interferon Genes Statuses”
by Alina Drzyzga, Justyna Czapla, Sybilla Matuszczak, Barbara Łasut-Szyszka, Tomasz Cichoń, Ewelina Pilny, Magdalena Jarosz-Biej and Ryszard Smolarczyk
Cancers 2025, 17(2), 175; https://doi.org/10.3390/cancers17020175
Available online: https://www.mdpi.com/2072-6694/17/2/175

“A Review of Telomere Attrition in Cancer and Aging: Current Molecular Insights and Future Therapeutic Approaches”
by Mina Iskandar, Miguel Xiao Barbero, Muhamed Jaber, Roy Chen, Romulo Gomez-Guevara, Edwin Cruz and Sandy Westerheide
Cancers 2025, 17(2), 257; https://doi.org/10.3390/cancers17020257
Available online: https://www.mdpi.com/2072-6694/17/2/257

Special Issues

Tumor Microenvironment: Cellular Dynamics, Molecular Players, and Mechanisms of Therapy Resistance
Guest Editors: Dr. Teresa Gagliano, Dr. Angeliki Ditsiou and Dr. Viviana Vella
Submission deadline: 31 December 2026

Tumor Suppressor and Targeted Therapy in Hepatocellular Carcinoma: From Diagnosis to Treatment (2nd Edition)
Guest Editors: Prof. Dr. Ching-Sheng Hsu, Dr. Po-Heng Chuang and Dr. I-Cheng Lee
Submission deadline: 30 August 2026

Beyond PEGylation: Next-Generation Nanomedicine for Cancer Therapy
Guest Editor: Dr. Soumen Saha
Submission deadline: 30 September 2026

The Tumor Microenvironment and Its Role in Tumor Growth and Angiogenesis—2nd Edition
Guest Editor: Dr. Roberto Tamma
Submission deadline: 31 October 2026

You can view and submit relevant papers to Cancers via the following link:
https://www.mdpi.com/journal/cancers

Cancers Editorial Office

23 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Infectious Agents and Cancer


We are delighted to share a collection of highly viewed papers on infectious agents and cancer that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

The list of relevant papers can be seen below:

“An Assessment of Young Adults’ Awareness and Knowledge Related to the Human Papillomavirus (HPV), Oropharyngeal Cancer, and the HPV Vaccine”
by Eric N. Davis and Philip C. Doyle
Cancers 2025, 17(3), 344; https://doi.org/10.3390/cancers17030344
Available online: https://www.mdpi.com/2072-6694/17/3/344

“Human Papillomavirus-Related Cutaneous Squamous Cell Carcinoma”
by Alejandra Sandoval-Clavijo, Ignasí Martí-Martí, Carla Ferrándiz-Pulido, Júlia Verdaguer-Faja, Ane Jaka and Agustí Toll
Cancers 2025, 17(5), 897; https://doi.org/10.3390/cancers17050897
Available online: https://www.mdpi.com/2072-6694/17/5/897

“Involvement of Oral Microbiome in the Development of Oral Malignancy”
by Hitoshi Isono, Shintaro Nakajima, Satoshi Watanabe, Aya K. Takeda, Haruka Yoshii, Ami Shimoda, Hisao Yagishita, Kenji Mitsudo and Mitomu Kioi
Cancers 2025, 17(4), 632; https://doi.org/10.3390/cancers17040632
Available online: https://www.mdpi.com/2072-6694/17/4/632

“Ozone–Oxygen Therapy to Prevent HPV-Related Cancers of the Lower Gynecological Tract in Infected Patients: The Rationale for Further Developments”
by Luca Roncati
Cancers 2025, 17(3), 543; https://doi.org/10.3390/cancers17030543
Available online: https://www.mdpi.com/2072-6694/17/3/543

“Infectious Agents and Esophageal Cancer: A Comprehensive Review”
by Ahan Bhatt, Hasan Musanna Zaidi, Radhashree Maitra and Sanjay Goel
Cancers 2025, 17(7), 1248; https://doi.org/10.3390/cancers17071248
Available online: https://www.mdpi.com/2072-6694/17/7/1248

“Epstein–Barr Infection, Hodgkin’s Lymphoma, and the Immune System: Insights into the Molecular Mechanisms Facilitating Immune Evasion”
by Eleni Tsotridou and Emmanouel Hatzipantelis
Cancers 2025, 17(9), 1481; https://doi.org/10.3390/cancers17091481
Available online: https://www.mdpi.com/2072-6694/17/9/1481

Special Issues

Human Carcinogens—Chemical Agents, Occupational Exposure and Health Impact
Guest Editor: Dr. Jun-Pyo Myong
Submission deadline: 31 August 2026

The Unseen Burden: Incidence and Outcomes of Infections in Leukemia
Guest Editors: Dr. Elisa Buzzatti and Dr. Maria Ilaria Del Principe
Submission deadline: 31 August 2026

HIV-Associated Lymphoid Neoplasms (2nd Edition)
Guest Editors: Dr. José-Tomás Navarro and Prof. Dr. Kai Hübel
Submission deadline: 20 July 2026

Infectious Agents and Oesophageal Cancer (2nd Edition)
Guest Editors: Prof. Shan Rajendra and Dr. Mohammed Rabiei
Submission deadline: 31 May 2026

You can view and submit relevant papers to Cancers via the following link:
https://www.mdpi.com/journal/cancers

Cancers Editorial Office

23 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Cancer Biomarkers


We are delighted to share a collection of highly viewed papers on cancer biomarkers that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

The list of relevant papers can be seen below:

Artificial Intelligence-Assisted Drug and Biomarker Discovery for Glioblastoma: A Scoping Review of the Literature
by
Luana Conte, Gerardo Caruso, Anil K. Philip, Federico Cucci, Giorgio De Nunzio, Donato Cascio and Maria Caffo
Cancers 2025, 17(4), 571; https://doi.org/10.3390/cancers17040571
Available online: https://www.mdpi.com/2072-6694/17/4/571

Exosome-Mediated Cellular Communication in the Tumor Microenvironment Imparts Drug Resistance in Breast Cancer
by
RamaRao Malla, Priyamvada Bhamidipati, Anuveda Sree Samudrala, Yerusha Nuthalapati, Vasudevaraju Padmaraju, Aditya Malhotra, Annah S. Rolig and Sanjay V. Malhotra
Cancers 2025, 17(7), 1167; https://doi.org/10.3390/cancers17071167
Available online: https://www.mdpi.com/2072-6694/17/7/1167

Novel Urinary Biomarkers for the Detection of Bladder Cancer
by
Matthijs Oyaert, Charles Van Praet, Charlotte Delrue and Marijn M. Speeckaert
Cancers 2025, 17(8), 1283; https://doi.org/10.3390/cancers17081283
Available online: https://www.mdpi.com/2072-6694/17/8/1283

Molecular Subtypes and Mechanisms of Breast Cancer: Precision Medicine Approaches for Targeted Therapies
by
Eduarda Carvalho, Sule Canberk, Fernando Schmitt and Nuno Vale
Cancers 2025, 17(7), 1102; https://doi.org/10.3390/cancers17071102  
Available online: https://www.mdpi.com/2072-6694/17/7/1102

The Impact of Progesterone Receptor Status on Survival Outcomes in Metastatic Breast Cancer Patients Treated with First-Line CDK4/6 Inhibitors
by
Murad Guliyev, Ali Kaan Güren, Emre Özge, Rumeysa Çolak, Nargiz Majidova, Gülin Alkan Şen, Shamkhal Safarov, Murat Günaltılı, Mehmet Cem Fidan, İlkay Gültürk et al.
Cancers 2025, 17(4), 693; https://doi.org/10.3390/cancers17040693  
Available online: https://www.mdpi.com/2072-6694/17/4/693

Evaluating Tumor Tissue Modified Viral (TTMV)-HPV DNA for the Early Detection of Anal Squamous Cell Carcinoma Recurrence
by
Rafi Kabarriti, Shane Lloyd, James Jabalee, Catherine Del Vecchio Fitz, Randa Tao, Tyler Slater, Corbin Jacobs, Sean Inocencio, Michael Rutenberg, Chance Matthiesen et al.
Cancers 2025, 17(2), 174; https://doi.org/10.3390/cancers17020174  
Available online: https://www.mdpi.com/2072-6694/17/2/174

Special Issues:

“Biomarkers for Gynecological Cancers”
Guest Editor: Dr. Apriliana Kartikasari
Submission deadline: 31 March 2026

“Predictive Biomarkers for Lung Cancer”
Guest Editor: Prof. Dr. Ole Hilberg
Submission deadline: 30 December 2025

“Biomarkers for Therapy Response in Gastrointestinal Malignancies: Predicting Outcomes and Personalizing Care”
Guest Editor: Dr. Devalingam Mahalingam
Submission deadline: 30 April 2026

“MicroRNA in Cancer: From Molecular Mechanisms to Therapeutic Applications”
Guest Editors: Prof. Dr. Girish Shukla and Dr. Sivakumar Vijayaraghavalu
Submission deadline: 31 May 2026

You can view and submit relevant papers to Cancers via the following link: https://www.mdpi.com/journal/cancers.

Cancers Editorial Office

23 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Cancer Pathophysiology


We are delighted to share a collection of highly viewed papers on cancer pathophysiology that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

Exploring the Genetic Orchestra of Cancer: The Interplay Between Oncogenes and Tumor-Suppressor Genes”
by Sajal Raj Singh, Rakesh Bhaskar, Shampa Ghosh, Bhuvaneshwar Yarlagadda, Krishna Kumar Singh, Prashant Verma, Sonali Sengupta, Mitko Mladenov, Nikola Hadzi-Petrushev, Radoslav Stojchevski et al.
Cancers 2025, 17(7), 1082; https://doi.org/10.3390/cancers17071082
Available online: https://www.mdpi.com/2072-6694/17/7/1082

“Translational Advances in Oncogene and Tumor-Suppressor Gene Research”
by Radoslav Stojchevski, Edward Agus Sutanto, Rinni Sutanto, Nikola Hadzi-Petrushev, Mitko Mladenov, Sajal Raj Singh, Jitendra Kumar Sinha, Shampa Ghosh, Bhuvaneshwar Yarlagadda, Krishna Kumar Singh et al.

Cancers 2025, 17(6), 1008; https://doi.org/10.3390/cancers17061008
Available online: https://www.mdpi.com/2072-6694/17/6/1008

“The HOX Gene Family’s Role as Prognostic and Diagnostic Biomarkers in Hematological and Solid Tumors”
by Kaci Kopec, Danielle Quaranto, Nicole R. DeSouza, Tara Jarboe, Humayun K. Islam, Augustine Moscatello, Xiu-Min Li, Jan Geliebter and Raj K. Tiwari
Cancers 2025, 17(2), 262; https://doi.org/10.3390/cancers17020262
Available online: https://www.mdpi.com/2072-6694/17/2/262

“Unique Molecular Alteration of Lobular Breast Cancer: Association with Pathological Classification, Tumor Biology and Behavior, and Clinical Management”
by Huina Zhang and Yan Peng

Cancers 2025, 17(3), 417; https://doi.org/10.3390/cancers17030417
Available online: https://www.mdpi.com/2072-6694/17/3/417

“Curcumin and Its Derivatives in Hepatology: Therapeutic Potential and Advances in Nanoparticle Formulations”
by Ersin Karatayli, Shifana C. Sadiq, Jörn M. Schattenberg, Stephan Grabbe, Bernhard Biersack and Leonard Kaps

Cancers 2025, 17(3), 484; https://doi.org/10.3390/cancers17030484
Available online: https://www.mdpi.com/2072-6694/17/3/484

“Histotripsy of Liver Tumors: Patient Selection, Ethical Discussions, and How We Do It”
by Melis Uysal, Chase J. Wehrle, Sangeeta Satish, Emily Knott, Hanna Hong, Erlind Allkushi, Andrea Schlegel, Eren Berber, Federico Aucejo, JaeKeun Kim et al.

Cancers 2025, 17(7), 1100; https://doi.org/10.3390/cancers17071100
Available online: https://www.mdpi.com/2072-6694/17/7/1100

Special Issues
Extracellular Matrix—Role in the Tumor Microenvironment and Impact on Cancer Therapy
Guest Editors: Dr. Heena Kumra and Dr. Makoto Noda
Submission deadline: 30 April 2026  
Advances in Pathology of Lymphoma and Leukemia
Guest Editor: Dr. Siba El Hussein
Submission deadline: 31 March 2026  
Genetics and Epigenetics of Gynecological Cancer
Guest Editor: Dr. Carmela De Marco
Submission deadline: 31 January 2026  
Pathology and Treatment of Triple-Negative Breast Cancer
Guest Editor: Dr. Ramadevi Subramani
Submission deadline: 31 January 2026  

You can view and submit relevant papers to Cancers via the following link: https://www.mdpi.com/journal/cancers.

Cancers Editorial Office

22 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Systematic Review or Meta-Analysis in Cancer Research


We are delighted to share a collection of highly viewed papers on systematic review or meta-analysis in cancer research that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

The list of relevant papers can be seen below:

Robotic Versus Laparoscopic Adrenalectomy for Adrenal Tumors: An Up-to-Date Meta-Analysis on Perioperative Outcomes
by
Giuseppe Esposito, Barbara Mullineris, Giovanni Colli, Serena Curia and Micaela Piccoli
Cancers 2025, 17(1), 150; https://doi.org/10.3390/cancers17010150
Available online: https://www.mdpi.com/2072-6694/17/1/150

Pancreaticobiliary Maljunction and Its Relationship with Biliary Cancer: An Updated and Comprehensive Systematic Review and Meta-Analysis on Behalf of TROGSS—The Robotic Global Surgical Society
by
Yeisson Rivero-Moreno, Aman Goyal, Victor Bolívar, Nnenna Osagwu, Sophia Echevarria,
José Gasca-Insuasti, Freddy Pereira-Graterol, Dagny von Ahrens, Omar Felipe Gaytán Fuentes, Luis Osvaldo Suárez-Carreón et al.
Cancers 2025, 17(1), 122; https://doi.org/10.3390/cancers17010122   
Available online: https://www.mdpi.com/2072-6694/17/1/122

Impact of Physical Exercise on Breast Cancer-Related Lymphedema and Non-Invasive Measurement Tools: A Systematic Review
by
Marta Arias-Crespo, Rubén García-Fernández, Natalia Calvo-Ayuso, Cristian Martín-Vázquez, Maria de Fátima da Silva Vieira Martins and Enedina Quiroga-Sánchez
Cancers 2025, 17(2), 333; https://doi.org/10.3390/cancers17020333
Available online: https://www.mdpi.com/2072-6694/17/2/333

Evaluating Tumour Mutational Burden as a Key Biomarker in Personalized Cancer Immunotherapy: A Pan-Cancer Systematic Review
by
Anca Zgura, Stefania Chipuc, Nicolae Bacalbasa, Bogdan Haineala, Anghel Rodica and Vâlcea Sebastian
Cancers 2025, 17(3), 480; https://doi.org/10.3390/cancers17030480
Available online: https://www.mdpi.com/2072-6694/17/3/480

Dark Topics on Giant Retroperitoneal Liposarcoma: A Systematic Review of 157 Cases
by
Alfonso Santangelo, Agostino Fernicola, Domenico Santangelo, Gaia Peluso, Armando Calogero, Felice Crocetto, Akbar Jamshidi, Luigi Pelosio, Alessandro Scotti, Vincenzo Tammaro et al.
Cancers 2025, 17(5), 740; https://doi.org/10.3390/cancers17050740
Available online: https://www.mdpi.com/2072-6694/17/5/740

Immune Checkpoint Inhibitor-Induced Pancreatic Injury (ICI-PI) in Adult Cancer Patients: A Systematic Review and Meta-Analysis
by
Cha Len Lee, Israt Jahan Riya, Ifrat Jahan Piya, Thiago Pimentel Muniz, Marcus Otho Butler and Samuel David Saibil
Cancers 2025, 17(7), 1080; https://doi.org/10.3390/cancers17071080
Available online: https://www.mdpi.com/2072-6694/17/7/1080

Special Issue:

Systematic Reviews and Meta-Analyses of Genitourinary Cancers (2nd Edition)
Guest Editors: Prof. Dr. Giorgio Treglia and Dr. Ursula Maria Vogl
Submission deadline: 31 July 2026

You can view and submit relevant papers to Cancers via the following link: https://www.mdpi.com/journal/cancers.

Cancers Editorial Office

22 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Clinical Research of Cancer


We are delighted to share a collection of highly viewed papers in clinical research of cancer that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

“Evaluating Offspring After Pregnancy-Associated Cancer: A Systematic Review of Neonatal Outcomes”
by Aida Petca, Lucia Elena Niculae, Raluca Tocariu, Aniela-Roxana Nodiți, Răzvan-Cosmin Petca and Ioana Cristina Rotar
Cancers 2025, 17(2), 299; https://doi.org/10.3390/cancers17020299
Available online: https://www.mdpi.com/2072-6694/17/2/299

“Treatment Quality of Rectal Cancer Patients in Certified Colorectal Cancer Centers Versus Non-Certified Hospitals: A Comparative Analysis”
by Paweł Mroczkowski, Henry Kusian, Olof Jannasch, Hans Lippert, Radosław Zajdel, Karolina Zajdel, Arkadiusz Sadowski and Anna Merecz-Sadowska

Cancers 2025, 17(1), 120; https://doi.org/10.3390/cancers17010120
Available online: https://www.mdpi.com/2072-6694/17/1/120

“Maxillectomy Guided by 3D Printing Versus Conventional Surgery for Patients with Head and Neck Cancer”
by Sung Yool Park, Sung Ha Jung, Anna Seo, Hakjong Noh, Hwansun Lee, Hyo Jun Kim, Younghac Kim, Man Ki Chung, Han-Sin Jeong, Chung-Hwan Baek et al.

Cancers 2025, 17(1), 140; https://doi.org/10.3390/cancers17010140
Available online: https://www.mdpi.com/2072-6694/17/1/140

UBR5 in Tumor Biology: Exploring Mechanisms of Immune Regulation and Possible Therapeutic Implications in MPNST
by Diana Akinyi Odhiambo, Selina Fan and Angela C. Hirbe

Cancers 2025, 17(2), 161; https://doi.org/10.3390/cancers17020161
Available online: https://www.mdpi.com/2072-6694/17/2/161

A Sequencing Overview of Malignant Peripheral Nerve Sheath Tumors: Findings and Implications for Treatment”
by Kangwen Xiao, Kuangying Yang and Angela C. Hirbe
Cancers 2025, 17(2), 180; https://doi.org/10.3390/cancers17020180
Available online: https://www.mdpi.com/2072-6694/17/2/180

“Clinical Benefit of Pegylated Liposomal Doxorubicin and High Prevalence of Pre-Existing Psychiatric Conditions in Patients with Desmoid-Type Fibromatosis”
by Andrea Espejo Freire and Keith M. Skubitz
Cancers 2025, 17(2), 293; https://doi.org/10.3390/cancers17020293
Available online: https://www.mdpi.com/2072-6694/17/2/293

Special Issues
Advances in Spine Oncology: Research and Clinical Studies
Guest Editor: Dr. Oluwaseun O. Akinduro
Submission deadline: 31 December 2025
Gynecological Cancer: Prevention, Diagnosis, Prognosis and Treatment
Guest Editors: Dr. Joanna P. Kacperczyk-Bartnik, Dr. Tibor Andrea Zwimpfer and Prof. Dr. Michał Ciebiera
Submission deadline: 20 December 2025
Optimizing Surgical Procedures and Outcomes in Renal Cancer
Guest Editors: Prof. Dr. Maciej Salagierski and Dr. Piotr Kania
Submission deadline: 20 December 2025
Advances in Clinical Trials: Outcome, Innovations, Challenges, and Ethical Practice. in Cancer Research 2024–2025
Guest Editors: Prof. Dr. Naoto T. Ueno and Prof. Dr. David R. Gandara
Submission deadline: 31 December 2025

You can view and submit relevant papers to Cancers via the following link: https://www.mdpi.com/journal/cancers.

Cancers Editorial Office

22 October 2025
Cancers | Highly Viewed Papers and Hot Topic Special Issues on Cancer Causes, Screening and Diagnosis


We are delighted to share a collection of highly viewed papers on cancer causes, screening and diagnosis that were published in Cancers (ISSN: 2072-6694) in the first half of 2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

“Innovative Approaches to Early Detection of Cancer-Transforming Screening for Breast, Lung, and Hard-to-Screen Cancers”
by Shlomi Madar, Reef Einoch Amor, Sharon Furman-Assaf and Eitan Friedman

Cancers 2025, 17(11), 1867; https://doi.org/10.3390/cancers17111867
Available online: https://www.mdpi.com/2072-6694/17/11/1867

“Glioblastoma: Clinical Presentation, Multidisciplinary Management, and Long-Term Outcomes”
by
David Sipos, Bence L. Raposa, Omar Freihat, Mihály Simon, Nejc Mekis, Patrizia Cornacchione and Árpád Kovács
Cancers 2025, 17(1), 146; https://doi.org/10.3390/cancers17010146
Available online: https://www.mdpi.com/2072-6694/17/1/146

“Targeting Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer: Beyond PD-1/PD-L1 Monoclonal Antibodies”
by
Nicolas Roussot, Courèche Kaderbhai and François Ghiringhelli
Cancers 2025, 17(5), 906; https://doi.org/10.3390/cancers17050906
Available online: https://www.mdpi.com/2072-6694/17/5/906

“Advances in Glioblastoma Diagnosis: Integrating Genetics, Noninvasive Sampling, and Advanced Imaging”
by
Ryan Gough, Randall W. Treffy, Max O. Krucoff and Rupen Desai
Cancers 2025, 17(1), 124; https://doi.org/10.3390/cancers17010124
Available online: https://www.mdpi.com/2072-6694/17/1/124

“Rising Trends in Prostate Cancer Among Asian Men: Global Concerns and Diagnostic Solutions”
by
Li-Chuan Ko, Nick Gravina, Joos Berghausen and Joe Abdo
Cancers 2025, 17(6), 1013; https://doi.org/10.3390/cancers17061013
Available online: https://www.mdpi.com/2072-6694/17/6/1013

“Exosomes in Precision Oncology and Beyond: From Bench to Bedside in Diagnostics and Therapeutics”
by Emile Youssef, Dannelle Palmer, Brandon Fletcher and Renee Vaughn
Cancers 2025, 17(6), 940; https://doi.org/10.3390/cancers17060940
Available online: https://www.mdpi.com/2072-6694/17/6/940

Special Issues:

Advances in Diagnostics and Treatments for Glioblastoma
Guest Editors: Dr. Sied Kebir and Dr. Manmeet Singh Ahluwalia
Submission deadline: 10 April 2026
Mass Spectrometry and Cancers
Guest Editors: Dr. Rita Casadonte and Dr. Kristina Schwamborn
Submission deadline: 15 May 2026
Breast Cancer Screening: Global Practices and Future Directions
Guest Editor: Dr. Rudolf Morant
Submission deadline: 15 May 2026
Digital Pathology in Precision Oncology: Emerging Tools for Diagnosis and Treatment Guidance
Guest Editors: Dr. Daniela Hartmann and Dr. Maximilian Deussing
Submission deadline: 25 June 2026

You can view and submit relevant papers to Cancers via the following link: https://www.mdpi.com/journal/cancers.

Cancers Editorial Office

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