The Treatment of Neonatal Hypoxic-Ischemic Encephalopathy

Dear Colleagues,

I would like to invite you to contribute an article to an upcoming Special Issue of Brain Sciences that will focus on the treatment and management of neonatal brain injury. Despite active research and development of numerous promising therapies including hypothermia, translation to the clinical setting has moved slowly. This issue will highlight new strategies for neuroprotection including advances in the treatment of neonatal seizures (should we be treating them at all?). Attention to other mechanisms of injury including the blood-brain barrier, peripheral inflammatory contributions and neuroinflammation may provide alternative avenues for neuroprotection. Repurposing of currently approved drugs is also gathering momentum but do we need thorough pre-clinical testing in neonatal models or should we progress directly to clinical trials?

I look forward to your contributions to this exciting issue so that together we can progress this important field to improve neonatal brain outcomes.

Dr. Tracey Bjorkman
Guest Editor

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