New Advances in Attention Deficit Hyperactivity Disorder (ADHD)

Dear Colleagues,

Attention deficit/hyperactivity disorder (ADHD) is a common and enduring neurodevelopmental disorder characterised by difficulties with inattention and/or hyperactivity and impulsivity. The condition affects around 5% of children and 3% of adults worldwide and is associated with reduced educational and occupational attainment, increased risk of physical and mental health problems and increased rates of criminality and substance misuse. Pharmacological treatments are available but are not universally effective or well-tolerated. Further research is needed to improve our understanding of the causes of this complex, heterogeneous condition and to develop more effective treatments.

ADHD likely reflects complex interactions between multiple low-risk genetic variants and environmental factors. Evidence of alterations in the function and structure of the brain gives some indication of the neuropathology of the condition and offers hope for the development of biomarkers to aid diagnosis and guide treatment development. Further research is needed, however, to better characterise the pathology of the condition, including the co-occurrence of ADHD with other neurodevelopmental disorders, and to accelerate the development of more effective therapies.

This Special Issue of Brain Sciences will present recent advances in the field of ADHD, focussing in particular on research that seeks to clarify the pathology of the condition (including co-occurrence with other disorders), to identify therapeutic targets or to assess treatment efficacy.

Dr. Maddie Groom
Dr. Elizabeth Shephard
Guest Editors

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