Enzymes and Their Biotechnological Applications

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: closed (30 June 2013) | Viewed by 325888

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Clinical Hospital of Porto Alegre (HCPA), affiliated with the Federal University of Rio Grande do Sul, Porto Alegre 91501-970, Brazil
Interests: microbiome; molecular microbiology; metagenomics; omics; biostatistics; next-generation sequencing; clinical research; bioinformatics; biotechnology; system biology; grand challenges
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Special Issue Information

Dear Colleagues,

The development of new enzymes is one of the most thriving branches of biotechnology. Although the applications of enzymes are already well established in some areas, recent advances in modern biotechnology have revolutionized the development of new enzymes. The use of genetic engineering has further improved manufacturing processes and enabled the commercialization of enzymes that could previously not be produced. Protein engineering and the possibility of introducing small changes to proteins are bringing ever more powerful means of analysis to the study of enzyme structure and its biochemical and biophysical properties, which have leading to the rational modification of enzymes to match specific requirements and also the design of new enzymes with novel properties. The developments in bioinformatics and the availability of sequence data have significantly increased the efficiency of identifying genes with biotech potential from nature. Complementary to chemical synthesis, biosynthesis of drug metabolites with mammalian or microbial bioreactors offers certain advantages, and sometime is the only practical route to the desired metabolite. At the same time, new technological developments are stimulating the chemical and pharmaceutical industry to embrace enzyme technology. Altogether, these advances have made it possible to provide tailor-made enzymes displaying new activities and adapted to new process conditions, enabling a further expansion of their use in several branches of biotechnology. This Special Issue focuses on the discovery and development of new enzymes and their applications in different areas of biotechnology. The Special Issue will contain a collection of papers written by authors who are leading experts in the field including selected papers from the 4th International Symposium on Enzymes & Biocatalysis (SEB-2013). We cordially welcome you to join us in this endeavor. The submission of comprehensive reviews or original research articles is most welcome. It is an opportunity to take part in and to influence future trends in one of the fastest growing fields of research.

Professor Pabulo Henrique Rampelotto
Guest Editor

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Keywords

  • biocatalysis polymerization and polymer synthesis
  • biocatalysis synthesis of chiral molecules
  • biocatalytic technologies
  • enzyme biosensor
  • enzyme inhibitors
  • environmental enzymology
  • enzymatic protein engineering technology
  • extremophilic enzymes
  • functional genomics and bioinformatics for novel enzymes
  • industrial biotechnology
  • new enzyme development
  • pharmaceutical biotechnology
  • structural and functional characterization of enzymes

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Published Papers (21 papers)

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23 pages, 310 KiB  
Review
Microbial Enzymes: Tools for Biotechnological Processes
Biomolecules 2014, 4(1), 117-139; https://doi.org/10.3390/biom4010117 - 16 Jan 2014
20 pages, 659 KiB  
Review
Research Applications of Proteolytic Enzymes in Molecular Biology
Biomolecules 2013, 3(4), 923-942; https://doi.org/10.3390/biom3040923 - 8 Nov 2013
16 pages, 425 KiB  
Review
Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors
Biomolecules 2013, 3(4), 889-904; https://doi.org/10.3390/biom3040889 - 1 Nov 2013
19 pages, 764 KiB  
Review
Biotechnological Applications of Transglutaminases
Biomolecules 2013, 3(4), 870-888; https://doi.org/10.3390/biom3040870 - 22 Oct 2013
36 pages, 674 KiB  
Review
Biocatalysis for Biobased Chemicals
Biomolecules 2013, 3(4), 812-847; https://doi.org/10.3390/biom3040812 - 17 Oct 2013
34 pages, 1286 KiB  
Review
Improvement of Biocatalysts for Industrial and Environmental Purposes by Saturation Mutagenesis
Biomolecules 2013, 3(4), 778-811; https://doi.org/10.3390/biom3040778 - 8 Oct 2013
37 pages, 3082 KiB  
Review
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
Biomolecules 2013, 3(4), 741-777; https://doi.org/10.3390/biom3040741 - 2 Oct 2013
41 pages, 1451 KiB  
Review
Quantum Mechanical Modeling: A Tool for the Understanding of Enzyme Reactions
Biomolecules 2013, 3(3), 662-702; https://doi.org/10.3390/biom3030662 - 23 Sep 2013
11 pages, 398 KiB  
Article
Production of Fungal Glucoamylase for Glucose Production from Food Waste
Biomolecules 2013, 3(3), 651-661; https://doi.org/10.3390/biom3030651 - 19 Sep 2013
19 pages, 704 KiB  
Review
Arming Technology in Yeast—Novel Strategy for Whole-cell Biocatalyst and Protein Engineering
Biomolecules 2013, 3(3), 632-650; https://doi.org/10.3390/biom3030632 - 9 Sep 2013
20 pages, 294 KiB  
Review
Fungal Beta-Glucosidases: A Bottleneck in Industrial Use of Lignocellulosic Materials
Biomolecules 2013, 3(3), 612-631; https://doi.org/10.3390/biom3030612 - 3 Sep 2013
15 pages, 173 KiB  
Review
Microbial Enzymes with Special Characteristics for Biotechnological Applications
Biomolecules 2013, 3(3), 597-611; https://doi.org/10.3390/biom3030597 - 23 Aug 2013
19 pages, 344 KiB  
Review
Decarboxylation of Pyruvate to Acetaldehyde for Ethanol Production by Hyperthermophiles
Biomolecules 2013, 3(3), 578-596; https://doi.org/10.3390/biom3030578 - 21 Aug 2013
15 pages, 606 KiB  
Article
A Sensitive DNA Enzyme-Based Fluorescent Assay for Bacterial Detection
Biomolecules 2013, 3(3), 563-577; https://doi.org/10.3390/biom3030563 - 20 Aug 2013
10 pages, 139 KiB  
Review
Carbonic Anhydrases and Their Biotechnological Applications
Biomolecules 2013, 3(3), 553-562; https://doi.org/10.3390/biom3030553 - 19 Aug 2013
18 pages, 511 KiB  
Article
Pyranose Dehydrogenase from Agaricus campestris and Agaricus xanthoderma: Characterization and Applications in Carbohydrate Conversions
Biomolecules 2013, 3(3), 535-552; https://doi.org/10.3390/biom3030535 - 16 Aug 2013
21 pages, 860 KiB  
Article
Lipases Immobilization for Effective Synthesis of Biodiesel Starting from Coffee Waste Oils
Biomolecules 2013, 3(3), 514-534; https://doi.org/10.3390/biom3030514 - 13 Aug 2013
20 pages, 1232 KiB  
Article
Enzyme-Catalyzed Synthesis of Unsaturated Aliphatic Polyesters Based on Green Monomers from Renewable Resources
Biomolecules 2013, 3(3), 461-480; https://doi.org/10.3390/biom3030461 - 12 Aug 2013
12 pages, 302 KiB  
Article
Enantiocomplementary Yarrowia lipolytica Oxidoreductases: Alcohol Dehydrogenase 2 and Short Chain Dehydrogenase/Reductase
Biomolecules 2013, 3(3), 449-460; https://doi.org/10.3390/biom3030449 - 12 Aug 2013
17 pages, 662 KiB  
Review
Architecture of Amylose Supramolecules in Form of Inclusion Complexes by Phosphorylase-Catalyzed Enzymatic Polymerization
Biomolecules 2013, 3(3), 369-385; https://doi.org/10.3390/biom3030369 - 11 Jul 2013
17 pages, 348 KiB  
Review
Angling for Uniqueness in Enzymatic Preparation of Glycosides
Biomolecules 2013, 3(2), 334-350; https://doi.org/10.3390/biom3020334 - 13 Jun 2013
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