Biomimetic Coating Technologies and Biomaterials for Orthopedic Implants

A special issue of Biomimetics (ISSN 2313-7673). This special issue belongs to the section "Biomimetics of Materials and Structures".

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 1696

Special Issue Editors

Special Issue Information

Dear Colleagues,

We are delighted to announce the Special Issue of Biomimetics, titled “Biomimetic Coating Technologies and Biomaterials for Orthopedic Implants”, exploring the transformative roles of biomimetic coatings and technologies in modern medical practice.

This Special Issue will assemble a collection of high-quality advancements in the field of medical research, specifically focusing on innovative biomimetic coating technologies and biomaterials designed to enhance orthopedic implant performances.

In the dynamic landscape of modern medicine, biomimetic coatings and technologies have emerged as key players for advancing orthopedic implantology. This Special Issue is dedicated to providing a comprehensive platform for researchers, practitioners, and academicians to contribute cutting-edge reviews and scientific papers. Submissions that explore diverse facets, including material design, innovative coating techniques, biocompatibility assessments, and clinical applications, are, therefore, highly encouraged as they will most significantly contribute to the advancement of biomimetic technologies in orthopedic implantology.

Nowadays, biomimetic coatings and materials are extensively designed to replicate the natural composition and structure of bone tissue. They provide a supportive environment for cell adhesion, proliferation, and differentiation. These innovations will address significant challenges in the field of orthopedic implantology, such as implant loosening, infection, and/or insufficient osseointegration.

We welcome submissions that cover, but are not limited to, the following research areas:

  • Biomimetic coatings: advances in coating technologies that improve the surface properties of implants, including but not limited to hydroxyapatite, bioactive glasses, and/or composite coatings;
  • Novel biomaterials: development and characterization of advanced biomaterials, such as biodegradable polymers, (nano)composites, and bioactive ceramics, designed to mimic the extracellular matrix;
  • Surface modification techniques: innovations in surface modification techniques, such as plasma spraying, electrospinning, and/or chemical vapor deposition, to enhance biological responses;
  • Biofunctionalization: functionalization of implant surfaces with peptides, growth factors, and other bioactive molecules to promote osseointegration and tissue regeneration;
  • Nanotechnology in orthopedics: utilization of nanotechnology to create nanostructured surfaces and materials that enhance cellular interactions and implant performance.

As demand for orthopedic implants with improved performance, longevity, and biocompatibility continues to grow, the goal of this Special Issue is, thus, to showcase the latest advancements in biomimetic approaches and their significant roles in addressing these challenges.

We look forward to receiving your invaluable reviews and scientific papers in order to make this Special Issue a pivotal resource for advancing biomimetic technologies in orthopedic implantology. Please refer to our submission guidelines for details on manuscript preparation and submission.

Dr. Liviu Duta
Dr. Valentina Grumezescu
Guest Editors

Manuscript Submission Information

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Keywords

  • biomimetic coatings
  • innovative coating technologies
  • advanced biomaterials
  • natural/synthetic polymers with bioactive properties
  • tissue regeneration
  • biocompatibility assessment
  • nanofibers in orthopedic implants
  • in vitro and in vivo testing

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Published Papers (1 paper)

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Research

14 pages, 8975 KiB  
Article
Development and Evaluation of Fucoidan-Loaded Electrospun Polyvinyl Alcohol/Levan Nanofibers for Wound Dressing Applications
by Natavan Ismayilova, Muhammad Khaqan Zia, Hatice Selen Akkaya, Songul Ulag, Yeliz Guldorum, Ebru Toksoy Oner, Erol Ince, Liviu Duta and Oguzhan Gunduz
Biomimetics 2024, 9(9), 508; https://doi.org/10.3390/biomimetics9090508 - 23 Aug 2024
Viewed by 1292
Abstract
Wound dressing is an ancient technique for promoting healing, and modern technology has led to the development of advanced dressings that enhance patient care. Nanofiber-based wound dressings are a medical innovation with enhanced properties, including improved adhesion, reduced infection rates, and increased tissue [...] Read more.
Wound dressing is an ancient technique for promoting healing, and modern technology has led to the development of advanced dressings that enhance patient care. Nanofiber-based wound dressings are a medical innovation with enhanced properties, including improved adhesion, reduced infection rates, and increased tissue regeneration. This article focuses on electrospun nanofibrous wound dressing materials produced using the widely adopted method of electrospinning. This article explores several parameters that influence fiber size, including electrical conductivity, electric potential, collector distance, viscosity, flow rate, and surface tension. With Fucoidan (FUC) loading, an increase in the fiber diameter of the control group from 310 nm to 395 nm was observed. This research also examines the use of Halomonas Levan (HL), a polysaccharide, and polyvinyl alcohol (PVA) polymer as wound dressing materials to enhance the mechanical properties of the latter. The incorporation of various concentrations of FUC into PVA-HL electrospun nanofibers yielded diverse effects on tensile strength: an enhancement was observed in the PVA-HL-10FUC formulation, while reductions were noted in the PVA-HL-13FUC and PVA-HL-15FUC formulations. The WST1 assay demonstrated that none of the samples exhibited cytotoxicity up to 72 h, as cell viability increased over time. In conclusion, nanofibrous PVA-HL structures loaded with FUC, which promote tissue regeneration and prevent infection, could be considered a novel wound dressing material. Full article
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