MicroRNA in Solid Tumor and Hematological Diseases 3.0

Dear Colleagues,

MicroRNAs (miRNAs), short non-coding RNA, are involved in physiologic and pathologic processes. They are critically involved in a wide number of processes, such as differentiation, development, inflammation, immune response, and cancer. MiRNAs play a key role in cancer pathogenesis by inhibiting gene expression at the post-transcriptional level. Moreover, miRNAs are differentially expressed in tumors compared to normal human tissues, and they can be divided into oncomiRNAs and tumor suppressor miRNAs, although some miRNAs can play both roles depending on the cellular context. As a potential therapeutic approach for cancer, extensive studies have demonstrated how to deregulate the small non-coding transcriptome, whether down-regulating the expression of oncogenic miRNAs or overexpressing tumor-suppressive miRNAs. Therefore, accurate analysis of miRNAs expression from cancer patients might be a useful tool to develop personalized medicine in the future.

This Special Issue will focus on the role of miRNAs in controlling pivotal biological mechanisms that lead to oncogenic transformation and tumor formation, growth, and dissemination, as well as their diagnostic and prognostic significance in different cancer subtypes. Original research manuscripts and comprehensive reviews are both welcome for this call.

Dr. Francesca Lovat
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.