New Methods and Applications in the Study of Bone Histomorphometry and Biomechanics
Deadline for manuscript submissions: closed (15 February 2023) | Viewed by 23978
Interests: forensic medicine; forensic pathology; forensic anthropology
Special Issues, Collections and Topics in MDPI journals
Interests: forensic anthropology; biological anthropology; bone histomorphometry; skeletal variation; aging; bone pathology
Bone is a resistant and dynamic tissue that undergoes constant changes throughout life, and is subject to various factors, such as growth, development, mechanical loading, diet and pathology. Bone is a valuable diagnostic tool in forensic medicine and forensic anthropology, due to its unique properties, and it can be used to extract crucial information when investigating unknown, heavily decomposed remains. Bone is analysed by observing its microscopic structure, as well as quantifying its structural elements and material properties, which provides an alternative methodological perspective that allows bone to be fully understood at the tissue level. Research has demonstrated that bone histomorphometry can assist in the identification process, with methods being developed for the purpose of species differentiation, age estimation and histo-taphonomy assessment. Research pertaining to bone biomechanics explores the material and mechanical properties of bone, providing insights into bone behavior in relation to fracture, trauma assessment and interpretation, as well as age-related changes. Moreover, both methodological approaches offer the possibility of evaluating the impact of pathological conditions on bone, intra and inter-individual skeletal variation, as well as other relevant information, such as physical activity. In addition to the recent developments in X-ray-based imaging, a number of techniques, based on metric, histomorphometric and simulated mechanical analyses, have attracted great interest for forensic purposes, due to their noninvasive nature. High-resolution imaging techniques can provide three-dimensional information, in addition to the classical two-dimensional techniques on bone remodeling and microstructure, and can also accommodate biomechanical studies of relevant nature. This Special Issue aims to collect important contributions in the field of histomorphometry and biomechanics, highlighting the potential of the latest state-of-the-art methodologies, in order to meet the challenges in forensic and medical sciences.
Dr. Elena F. Kranioti
Dr. Julieta Gómez García-Donas
Dr. Andrea Bonicelli
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- age estimation
- sex estimation
- intra- and inter-population variation
- trauma analysis
- bone modelling and remodeling
- bone histopathology
- validation and testing
- CT- and μCT-based histomorphometry
- automated methods for histomorphometric analysis
- bone biomechanics
- bone diagenesis
- simulation and modelling