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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Dental Implant Reconstruction and Biomechanical Evaluation, 3rd Edition

edited by

Bongju Kim

submission deadline 30 Nov 2026 | Viewed by 79 | Submission Open

Keywords: dental materials; dental implants; dental prosthesis; implant-supported prosthesis; FEA; FEM; computational modelling; biomechanical characterization

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Approaches to Microalgae-Based Systems

edited by

Eduardo Jacob-Lopes

and Mariane Bittencourt Fagundes

submission deadline 1 Dec 2026 | Viewed by 235 | Submission Open

Keywords: metabolic engineering; cellular systems; bioprocess and bioproducts; multi-scale strategies; modeling and optimization; sustainable biotechnology; translational applications

(This special issue belongs to the Section Biochemical Engineering)

Rehabilitative Assessment Approaches for Disabilities

edited by

Saeid Sanei

and Tracey KM Lee

submission deadline 30 Dec 2026 | Viewed by 207 | Submission Open

Keywords: biosignal processing; deep learning; body sensor networks; gait; EEG; EMG; machine learning; rehabilitative assessment; vision techniques

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Plastic and Reconstructive Surgery: Innovations and Clinical Applications

edited by Cesar Abraham Gomez-Cabello and

Antonio Jorge Forte

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3025 | Submission Open

Keywords: artificial intelligence; machine learning; plastic surgery; reconstructive surgery; surgical planning; risk stratification; outcome prediction; postoperative monitoring

(This special issue belongs to the Section Biosignal Processing)

Transcranial Direct Current Stimulation: Bridging Bioengineering and Neuroscience for Brain Health

edited by

Josué Fernández-Carnero

and

Víctor Navarro López

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2389 | Submission Open

Keywords: transcranial direct current stimulation (tDCS); neuroplasticity; neuromodulation

(This special issue belongs to the Section Biosignal Processing)

Deep Learning for Medical Applications: Challenges and Opportunities

edited by

Roberta Hlavata

, Robert Hudec and

Patrik Kamencay

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2157 | Submission Open

Keywords: deep neural networks; deep learning; machine learning; medical applications; healthcare AI; medical imaging; multimodal data integration; model interpretability

(This special issue belongs to the Section Biosignal Processing)

Advancements in Human–Machine Interaction and Robotics: From Biomechanics to Cognitive Neuroscience

edited by Jiejunyi Liang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2110 | Submission Open

Keywords: human-machine interaction; robotics; biomechanics; cognitive neuroscience; anthropomorphic robotic systems

Advances and Clinical Applications of Anterior Segment Imaging Techniques—2nd Edition

edited by

Sang Beom Han

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1981 | Submission Open

Keywords: anterior segment; cornea; cataract; conjunctiva; anterior segment imaging; refractive surgery

Biomaterials for Cartilage and Bone Tissue Engineering: Third Edition

edited by

Francesca Scalera

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1228 | Submission Open

Keywords: cartilage; bone; scaffolds; stem cells; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Strategies for Microbial Bioprocess Optimization

edited by

Razieh Rafieenia

and

Sajad Shokri

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1042 | Submission Open

Keywords: metabolic engineering; fermentation; synthetic biology; bioreactor design; synthetic microbial communities; machine learning based process design; renewable substrates; life cycle assessment

(This special issue belongs to the Section Biochemical Engineering)

Cell Therapy and Tissue Engineering for Orthopedic Applications

edited by

Federica Banche-Niclot

and Patrick McCulloch

submission deadline 31 Dec 2026 | 1 articles | Viewed by 567 | Submission Open

Keywords: orthopedics and sports medicine; musculoskeletal regeneration; cell therapy; extracellular vesicles; biomaterials; translational research

(This special issue belongs to the Section Regenerative Engineering)

Mathematical and Computational Models in Biomedical Science and Engineering (3rd Edition)

edited by

Sundeep Singh

Roderick Melnik

and Robert Gilmour

submission deadline 31 Dec 2026 | 1 articles | Viewed by 333 | Submission Open

Keywords: modeling and simulation; biomedical engineering; medical physics; multiphysics and multiscale models; biomedical therapy; neurotechnology; regenerative medicine; drug delivery; data-driven models; machine learning; patient-specific models

(This special issue belongs to the Section Biosignal Processing)

Quality-Controlled Skin Allografts and Acellular Dermal Matrices for Burns and Hard-to-Heal Wounds: State of the Art

edited by Linda Tognetti and

Elisa Pianigiani

submission deadline 31 Dec 2026 | Viewed by 292 | Submission Open

Keywords: quality-controlled skin allografts; acellular dermal matrices; skin allografts; wound-healing; hard-to-heal wounds; wound closure

(This special issue belongs to the Section Regenerative Engineering)

Multimodal and Explainable AI for Biomedical Imaging and Computer-Aided Diagnosis

edited by

Nesma Settouti

Mouloud Adel

and

Daniel L. Farkas

submission deadline 31 Dec 2026 | Viewed by 239 | Submission Open

Keywords: foundation models; transformers; multimodal AI; medical imaging; computer-aided diagnosis; biomedical image analysis; vision transformers; large language models; vision-language models; self-supervised learning; weakly supervised learning; explainable AI; trustworthy AI; federated learning; clinical decision support

(This special issue belongs to the Section Biosignal Processing)

Application of Deep Learning in Medical Image Classification and Segmentation for Precise Disease Diagnosis

edited by

Nadia Brancati

submission deadline 31 Dec 2026 | Viewed by 231 | Submission Open

Keywords: image analysis; disease classification; image segmentation; deep learning

(This special issue belongs to the Section Biosignal Processing)

Fundamentals of Orthopaedic Biomechanics: Implants, AI, and Innovation in Surgery—2nd Edition

edited by Farid Amirouche

submission deadline 31 Dec 2026 | Viewed by 223 | Submission Open

Keywords: orthopedics; biomechanics; implants; shoulder; knee; hip; hand and motion analysis; AI; augmented reality; ortho innovation

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advances in Surgical Devices and Medical Robotics

edited by Donald Sorrells

submission deadline 31 Dec 2026 | Viewed by 217 | Submission Open

Keywords: robotics; tissue engineering; 3D printing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Implantable Sensors for Neuroengineering

edited by Mingxiang Gao,

Pietro Siciliano

and Fariba Karimi

submission deadline 31 Dec 2026 | Viewed by 209 | Submission Open

Keywords: implantable sensors; wireless bioelectronics; implantable antennas; flexible bioelectronics; neuroengineering; neural interfaces; brain– computer interface; neuromodulation; neural prosthetics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

IoT Technology in Bioengineering Applications: Third Edition

edited by

Mihaela Hnatiuc

and

Larbi Boubchir

submission deadline 31 Dec 2026 | Viewed by 160 | Submission Open

Keywords: robotic device; signal processing; image processing; communication protocol; embedded system; smart sensors; cloud/FOG; predictive methods; monitoring; process optimization; diagnosis; implant; telesurgery; teleconsultation; telemonitoring

(This special issue belongs to the Section Biosignal Processing)

Magnetic/Electromagnetic Fields for Novel Therapeutic and Rehabilitation Applications

edited by

Alfredo Franco-Obregón

and Yee Kit Tai

submission deadline 31 Dec 2026 | Viewed by 159 | Submission Open

Keywords: magnetic fields; electromagnetic fields; EMF devices; rehabilitation; muscle magnetic therapy; cancer treatment; regenerative medicine; metabolic health

(This special issue belongs to the Section Biosignal Processing)

Advances in Magnetic Resonance Imaging: Hardware, Imaging Techniques, and Image Processing

edited by Sheng Shen and Hongwei Bran Li

submission deadline 31 Dec 2026 | Viewed by 154 | Submission Open

Keywords: magnetic resonance imaging (MRI); MRI instrumentation; low-field and ultra-low-field MRI; computational MRI reconstruction; artificial intelligence for MRI

(This special issue belongs to the Section Biosignal Processing)

Scalable Manufacturing for Cell and Gene Therapy

edited by

Min D. Tang-Schomer

submission deadline 31 Dec 2026 | Viewed by 141 | Submission Open

Keywords: bioprocess; cell and gene manufacturing; AAVs; iPSCs; organoids; viral vector production; stem cell production; lentiviral vectors; patient-derived; predictive models; oligonucleotide production; lipid nanoparticle production; mRNA production

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Beyond the Bench: Cutting-Edge Sensing and Identification of Emergent Environmental and Clinical Stressors

edited by Longyan Chen, Yi Chen and

Liu Cao

submission deadline 31 Dec 2026 | Viewed by 128 | Submission Open

Keywords: microplastic detection; nanoplastic detection; polyfluoroalkyl substances (PFAS) detection; anthropogenic stressors; machine learning; trace-level detection; human biofluid analysis; environmental health monitoring; predictive toxicology; high-throughput screening; AI-driven sensing

(This special issue belongs to the Section Biochemical Engineering)

Engineering Microalgal Systems for a Greener Future, 2nd Edition

edited by

Alok Kumar Patel

and

Ana Filipa Cruz Esteves

submission deadline 31 Dec 2026 | Viewed by 105 | Submission Open

Keywords: artificial intelligence; machine learning; bioprocessing; circular bioeconomy; production value addition; biomass valorization; microalgal cultivation systems; sustainable bioprocessing

(This special issue belongs to the Section Biochemical Engineering)

Intelligent Wearable and Implantable Devices for Biomedical Applications, 2nd Edition

edited by Milad Zamani and Yasser Rezaeiyan

submission deadline 31 Dec 2026 | Viewed by 96 | Submission Open

Keywords: bio-inspired and neuromorphic computation; spiking neural networks and event-driven processing; edge AI and on-device intelligence; biosensors and multimodal sensing systems; biosensor interface and front-end circuits; bioelectronics and biocompatible systems; biotelemetry and wireless biomedical communication; brain-computer interfaces and neural interfacing; closed-loop systems and neuromodulation; energy-efficient and ultra-low-power design; flexible; organic; and emerging electronic materials; personalized healthcare and continuous monitoring; security and privacy in biomedical systems

(This special issue belongs to the Section Biosignal Processing)

Advances in Computational Oncology: Mathematical Modeling, Numerical Methods, and Intelligent Systems

edited by

Pasquale De Luca

and

Annabella Di Mauro

submission deadline 31 Dec 2026 | Viewed by 10 | Submission Open

Keywords: tumor modeling; numerical methods for PDEs; deep learning in oncology; physics-informed neural networks; chemotaxis– reaction– diffusion systems; tumor angiogenesis; high-performance computing; positivity-preserving schemes; neural operators; fractional differential equations; multi-scale biological models; GPU-accelerated simulation; computational oncology; uncertainty quantification

(This special issue belongs to the Section Biosignal Processing)

Biomaterials for Cardiovascular Repair

edited by Gabriel Converse

submission deadline 15 Jan 2027 | Viewed by 152 | Submission Open

Keywords: cardiovascular biomaterials; vascular graft; heart valve; endothelialization; calcification; thrombosis; PFAS

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Orthopedic Biomechanics Applied to Implant Design

edited by

Ghais Kharmanda

submission deadline 30 Jan 2027 | Viewed by 133 | Submission Open

Keywords: orthopedics; implant design; biomechanics; finite element method; optimal implant design; reliable implant design

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Electromagnetic Fields in Bioengineering: Advancing the One Health Paradigm

edited by

Marta Bonato

Silvia Gallucci

and

Emma Chiaramello

submission deadline 31 Jan 2027 | 2 articles | Viewed by 3497 | Submission Open

Keywords: biological tissue-EMF interactions; bioelectromagnetism; OneHealth; environmental health; therapeutic and diagnostic EMF applications; EMF safety in medicine; RF/mm-wave medical technologies

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Biomedical Diagnosis and Prognosis: Third Edition

edited by

NIkolaos Papandrianos

and

Ioannis D. Apostolopoulos

submission deadline 31 Jan 2027 | 3 articles | Viewed by 3364 | Submission Open

Keywords: medical diagnosis; medical prognosis; medical AI; machine learning; deep learning; pervasive AI medical systems

(This special issue belongs to the Section Biosignal Processing)

Novel MRI Techniques and Biomedical Image Processing: Second Edition

edited by Dilbag Singh

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2007 | Submission Open

Keywords: MRI; image generation; image processing; image acquisition; image reconstruction; machine learning; deep learning

(This special issue belongs to the Section Biosignal Processing)

Advanced Biofabrication for Next-Generation Biomedical Devices and Tissues

edited by

Changchun Zhou

submission deadline 31 Jan 2027 | Viewed by 253 | Submission Open

Keywords: 3D bioprinting; biofabrication; tissue engineering; biomedical devices; additive manufacturing; regenerative medicine; smart biomaterials

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Development of Polymeric Materials for Biomedical Applications

edited by

Hidenori Otsuka

and

Arghya Sett

submission deadline 31 Jan 2027 | Viewed by 144 | Submission Open

Keywords: polymeric materials; 3D bioprinting; drug delivery systems; tissue engineering; biodegradable polymers; smart materials

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Machine Learning and Medical IoT in Healthcare

edited by Saadullah Farooq Abbasi and Chenxi Huang

submission deadline 30 Mar 2027 | Viewed by 256 | Submission Open

Keywords: digital health; medical IoT; machine learning; convolutional neural networks (CNN); biosignal processing; disease detection and diagnosis; explainable AI; remote monitoring system; medical devices; clinical decision support; medical image

(This special issue belongs to the Section Biosignal Processing)

Robotic-Assisted Gait Rehabilitation

edited by

Jung-Ho Lee

submission deadline 30 Mar 2027 | Viewed by 121 | Submission Open

Keywords: robot; gait; rehabilitation; engineering; exoskeleton; gait analysis; functional activity; motor recovery; wearable technology

(This special issue belongs to the Section Biosignal Processing)

Machine Learning Applications in Cancer Diagnosis and Prognosis

edited by

Rizwan Qureshi

and Maliazurina Saad

submission deadline 31 Mar 2027 | 1 articles | Viewed by 2064 | Submission Open

Keywords: machine learning; deep learning; foundation models; generative AI; large language models (LLMs); responsible AI; explainable AI (XAI); cancer diagnosis and prognosis; medical imaging

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Biomedical Imaging and Biomedical Signal Processing: Second Edition

edited by

George A. Papakostas

and

Eleni Vrochidou

submission deadline 31 Mar 2027 | 1 articles | Viewed by 513 | Submission Open

Keywords: artificial intelligence; biomedical imaging; biomedical signal processing; machine learning; deep learning; image segmentation; image classification; signal analysis; pattern recognition; medical diagnostics

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Innovations for Physiological Monitoring and Human-Centered Health Applications

edited by

Miguel Valencia

and

Pranav Madhav Kuber

submission deadline 31 Mar 2027 | Viewed by 145 | Submission Open

Keywords: biomechanics; human movement science; machine learning; physiological signal acquisition; data science; assistive technology

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Strategies for Ophthalmic Diseases—2nd Edition

edited by

Jae Yong Kim

submission deadline 31 Mar 2027 | Viewed by 137 | Submission Open

Keywords: ophthalmic diseases; imaging technology; artificial intelligence; retinal regeneration; corneal implants; drug delivery

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Application of Bioengineering to Restorative Dentistry

edited by Carlos A. Jurado

submission deadline 31 Mar 2027 | Viewed by 29 | Submission Open

Keywords: digital dentistry; restorative dentistry; dental materials; minimally invasive dentistry

(This special issue belongs to the Section Regenerative Engineering)

The Integration of Generative AI and Multimodal Models for Diagnosis and Customized Design of Biomaterials

edited by

Zhao Qin

Laura Vergani

and

Federica Buccino

submission deadline 31 Mar 2027 | Viewed by 5 | Submission Open

Keywords: generative artificial intelligence; multimodal learning; physics-informed modeling; inverse design; structure– function relationships; biomaterial design; advanced manufacturing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

AI and Machine Learning in Medical Image Processing: Innovations and Applications—2nd Edition

edited by Neil K. Jairath and Vartan Pahalyants

submission deadline 30 Apr 2027 | Viewed by 14 | Submission Open

Keywords: artificial intelligence (AI) in medical image processing; machine learning (ML) in medical image processing; deep learning in medical image processing; computer vision in medical imaging; medical image segmentation; diagnostic imaging; disease detection in medical images; clinical decision support systems; histopathological image analysis; advanced techniques for cancer detection; segmentation; and classification; applications in breast; prostate; brain; and other cancer imaging using AI; detection and pattern recognition in medical imaging; imaging modalities (MRI; CT; ultrasound; X-ray); explainable AI (XAI) in healthcare; healthcare technology and innovation; predictive modeling in medical imaging; generative AI and large language models (LLMs) for medical imaging; big data analytics in healthcare; automated diagnosis systems; biomedical engineering applications; ethics and fairness in medical AI; systematic reviews in medical image analysis; medical imaging datasets and benchmarking

(This special issue belongs to the Section Biosignal Processing)

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