Advances in Brain Magnetic Resonance Imaging

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biosignal Processing".

Deadline for manuscript submissions: closed (15 November 2024) | Viewed by 2403

Special Issue Editors


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Guest Editor
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China
Interests: MRI; medical image analysis

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Guest Editor
Computer Science Department, Central South University, Changsha, China
Interests: brain MRI; machine learning

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to a Special Issue focused on the cutting-edge advancements in Brain MRI, encompassing innovative imaging methods, state-of-the-art MRI reconstruction techniques, and sophisticated MRI data analysis approaches.

Magnetic Resonance Imaging (MRI) has played a pivotal role in revolutionizing our understanding of the brain's structure and function. In recent years, significant strides have been made in this field, offering exciting opportunities for bioengineers and researchers to delve into the complexities of brain imaging. This Special Issue aims to provide a platform for sharing groundbreaking discoveries related to Brain MRI. We welcome submissions on a wide range of topics, including but not limited to:

  • Novel Brain MRI Acquisition Techniques;
  • Advanced MRI Reconstruction Algorithms;
  • Quantitative Susceptibility Mapping (QSM) and Phase Imaging;
  • Functional MRI (fMRI) and Connectivity Analysis;
  • Machine learning and deep learning Applications in MRI Analysis;
  • Neuroimaging Biomarkers for Disease Diagnosis and Progression;
  • Multimodal Imaging Integration and Fusion;
  • Clinical Applications of Brain MRI.

We encourage submissions that showcase interdisciplinary collaborations. We look forward to receiving your manuscripts and sharing your groundbreaking work with our readers.

Dr. Hongjiang Wei
Dr. Yang Gao
Guest Editors

Manuscript Submission Information

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Published Papers (2 papers)

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Research

14 pages, 3952 KiB  
Article
Multivariate Analyses with Two-Step Dimension Reduction for an Association Study Between 11C-Pittsburgh Compound B and Magnetic Resonance Imaging in Alzheimer’s Disease
by Atsushi Kawaguchi and Fumio Yamashita
Bioengineering 2025, 12(1), 48; https://doi.org/10.3390/bioengineering12010048 - 9 Jan 2025
Viewed by 700
Abstract
The neuropathological diagnosis of Alzheimer’s disease (AD) relies on amyloid beta (Aβ) deposition in brain tissues. To study the relationship between Aβ deposition and brain structure, as determined using 11C-Pittsburgh compound B (PiB) and magnetic resonance imaging (MRI), respectively, we developed a [...] Read more.
The neuropathological diagnosis of Alzheimer’s disease (AD) relies on amyloid beta (Aβ) deposition in brain tissues. To study the relationship between Aβ deposition and brain structure, as determined using 11C-Pittsburgh compound B (PiB) and magnetic resonance imaging (MRI), respectively, we developed a regression model with PiB and MRI data as the predictor and response variables, respectively, and proposed a regression method for studying the association between them based on a supervised sparse multivariate analysis with dimension reduction based on a composite paired basis function. By applying this method to imaging data of 61 patients with AD (age: 55–85), the first component showed the strongest correlation with the composite score, owing to the supervised feature. The spatial pattern included the hippocampal and parahippocampal regions for MRI. The peak value was observed in the posterior cingulate and precuneus for PiB. The differences in PiB scores among the diagnosis groups 12 months after PiB imaging were significant between the normal and AD groups (p = 0.0284), but not between the normal and mild cognitive impairment (MCI) groups or the MCI and AD groups (p = 0.3508). Our method may facilitate the development of a dementia biomarker from brain imaging data. Scoring imaging data allows for visualization and the application of traditional analysis, facilitating clinical analysis for better interpretation of results. Full article
(This article belongs to the Special Issue Advances in Brain Magnetic Resonance Imaging)
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13 pages, 5483 KiB  
Article
Using the Probability Density Function-Based Channel-Combination Bloch–Siegert Method Realizes Permittivity Imaging at 3T
by Jiajia Wang, Yunyu Gao and Sherman Xuegang Xin
Bioengineering 2024, 11(7), 699; https://doi.org/10.3390/bioengineering11070699 - 10 Jul 2024
Viewed by 1035
Abstract
Magnetic resonance electrical properties tomography (MR EPT) can retrieve permittivity from the B1+ magnitude. However, the accuracy of the permittivity measurement using MR EPT is still not ideal due to the low signal-to-noise ratio (SNR) of B1+ magnitude. In [...] Read more.
Magnetic resonance electrical properties tomography (MR EPT) can retrieve permittivity from the B1+ magnitude. However, the accuracy of the permittivity measurement using MR EPT is still not ideal due to the low signal-to-noise ratio (SNR) of B1+ magnitude. In this study, the probability density function (PDF)-based channel-combination Bloch–Siegert (BSS) method was firstly introduced to MR EPT for improving the accuracy of the permittivity measurement. MRI experiments were performed using a 3T scanner with an eight-channel receiver coil. The homogeneous water phantom was scanned for assessing the spatial distribution of B1+ magnitude obtained from the PDF-based channel-combination BSS method. Gadolinium (Gd) phantom and rats were scanned for assessing the feasibility of the PDF-based channel-combination BSS method in MR EPT. The Helmholtz-based EPT reconstruction algorithm was selected. For quantitative comparison, the permittivity measured by the open-ended coaxial probe method was considered as the ground-truth value. The accuracy of the permittivity measurement was estimated by the relative error between the reconstructed value and the ground-truth value. The reconstructed relative permittivity of Gd phantom was 52.413, while that of rat leg muscle was 54.053. The ground-truth values of relative permittivity of Gd phantom and rat leg muscle were 78.86 and 49.04, respectively. The relative error of average permittivity was 33.53% for Gd and 10.22% for rat leg muscle. The results indicated the high accuracy of the permittivity measurement using the PDF-based channel-combination BSS method in MR EPT. This improvement may promote the clinical application of MR EPT technology, such as in the early diagnosis of cancers. Full article
(This article belongs to the Special Issue Advances in Brain Magnetic Resonance Imaging)
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